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Nucleic Acids Research, 1984, Vol. 12, No. 1Part1 193-201
© 1984

MAIN-FRAME COMPUTERS

Simplified computer programs for search of homology within nucteotide sequences

Manfred Kröger* and Anneliese KrÖger-Block

Institut für Biologie III, Universität Freiburg Schanzlestrasse 1, D-7800 Freiburg im Breisgau, FRG

*To whom correspondence should be addressed

Received August 25, 1983. Four new computer programs for search of homology within nuc-leotide sequences are presented. The main scope of the program design is flexibility, independence of sequence length and the capability to be used by any molecular biologist without any prior computer experience. The programs offer a linear search, a search for maximal identity, an alignment along a given sequence and a search based on homology within the amino acid coding capacity of nucleotide sequences. The language is Fortran V. Copies are available on request.


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