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Nucleic Acids Research, 1984, Vol. 12, No. 1Part2 505-519
© 1984

MINICOMPUTERS

Computer methods to locate signals in nucleic acid sequences

Rodger Staden

MRC Laboratory of Molecular Biology, Medical Research Council Centre Hills Road, Cambridge CB2 2QH, UK

Received August 24, 1983. This paper describes computer methods for locating signals in nucleic acid sequences. The signals include ribosome binding sites, promoter sequences and splice junctions. The methods are of use both to those trying to interpret the function of newly determined sequences and to those studying the molecular mechanisms involved in the recognition of these special signal sequences.


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