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Nucleic Acids Research, 1984, Vol. 12, No. 1Part2 539-549
© 1984

MINICOMPUTERS

The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression

Michael Gribskov, John Devereux1 and Richard R. Burgess

McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Madison, WI 53706, USA 1Laboratory of Genetics, University of Wisconsin-Madison, Madison WI 53706, USA

Received August 18, 1983. The codon preference plot is useful for locating genes in sequenced DNA, predicting the relative level of their expression and for detecting DNA sequencing errors resulting in the insertion or deletion of bases within a coding sequence. The three possible reading frames are displayed in parallel along with the open reading frames and plots of the location of rare codons in each reading frame.


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