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Nucleic Acids Research, 1984, Vol. 12, No. 1Part2 551-567
© 1984

MINICOMPUTERS

Measurements of the effects that coding for a protein has on a DNA sequence and their use for finding genes

Rodger Staden

MRC Laboratory of Molecular Biology, Medical Research Council Centre Hills Road, Cambridge CB2 2QH, UK

Received July 11, 1983. Protein genes can be found either by searching the DNA sequence for signals such as ribosome binding sites or by looking for the effects that coding for a protein has on the coding sequence. This paper describes how these coding effects can be measured and used to detect protein coding regions.


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