Skip Navigation

This Article
Right arrow Print PDF (475K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (51)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Nogi, Y.
Right arrow Articles by Fukasawa, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nogi, Y.
Right arrow Articles by Fukasawa, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1984, Vol. 12, No. 24 9287-9298
© 1984

MOLECULAR BIOLOGY

Nucleotide sequence of the yeast regulatory gene GAL80

Yasuhisa Nogi and Toshio Fukasawa

Laboratory of Molecular Genetics, Keio University School of Medicnie Shinjuku-ku, Tokyo 160, Japan

Received October 26, 1984. Accepted November 20, 1984.

The GAL80 gene in Saccharomyces cerevisiae encodes a negative regulatory protein for the set of inducible genes involving metabolism of galactose and melibiose. We have determined the nucleotide sequence of GAL80 and its flanking regions and assigned the 5' end of its mRNA to the sequence. The deduced coding sequence for GAL80 protein contains 1305 nucleotides and the calculated molecular weight of the peptide chain is 48309. The 5' end of the GAL80 mRNA maps about 67 nucleotides upstream from the translation initiating ATG. We have also determined the nucleotide sequence of uninducible alleles GAL80s–0, GAL80s–1 and GAL80s–2 and found single base substitution in each of these mutant genes which would lead to alteration of amino acid in GAL80 protein.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 GeneticsHome page
K. Melcher
Mutational Hypersensitivity of a Gene Regulatory Protein: Saccharomyces cerevisiae Gal80p
Genetics, October 1, 2005; 171(2): 469 - 476.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
V. Pilauri, M. Bewley, C. Diep, and J. Hopper
Gal80 Dimerization and the Yeast GAL Gene Switch
Genetics, April 1, 2005; 169(4): 1903 - 1914.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
J. V. Pego, A. J. Kortstee, C. Huijser, and S. C.M. Smeekens
Photosynthesis, sugars and the regulation of gene expression
J. Exp. Bot., February 1, 2000; 51(90001): 407 - 416.
[Abstract] [Full Text]

Home page
 Mol. Cell. Biol.Home page
A. K. Sil, S. Alam, P. Xin, L. Ma, M. Morgan, C. M. Lebo, M. P. Woods, and J. E. Hopper
The Gal3p-Gal80p-Gal4p Transcription Switch of Yeast: Gal3p Destabilizes the Gal80p-Gal4p Complex in Response to Galactose and ATP
Mol. Cell. Biol., November 1, 1999; 19(11): 7828 - 7840.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
W. Zheng, H. E. Xu, and S. A. Johnston
The Cysteine-Peptidase Bleomycin Hydrolase Is A Member of the Galactose Regulon in Yeast
J. Biol. Chem., November 28, 1997; 272(48): 30350 - 30355.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K.-i. Yano and T. Fukasawa
Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae
PNAS, March 4, 1997; 94(5): 1721 - 1726.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.