Skip Navigation

This Article
Right arrow Print PDF (1005K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (61)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Lefranc, M.-P.
Right arrow Articles by Rabbitts, T.H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lefranc, M.-P.
Right arrow Articles by Rabbitts, T.H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1984, Vol. 12, No. 3 1303-1312
© 1984

MOLECULAR BIOLOGY

Human immunoglobulin heavy chain A2 gene allotype determination by restriction fragment length polymorphism

Marie-Paule Lefranc* and T.H. Rabbitts

MRC Laboratory of Molecular Biology Hills Road, Cambridge, CB2 2QH, UK

Received December 23, 1983. Accepted January 11, 1984.

The human immunoglobulin heavy chain a2 genes have two allelic forms or allotypes called A2m(1) and A2m(2). Previously, these allotypic markers have only been distinguishable by serology. Studies of the a2 genes, however, show that it is possible to differentiate between the allotypes by restriction enzyme site polymorphisms, both in the protein coding regions and in flanking regions. These polymorphic sites have been used to determine the a2 allotypes of several human DNAs.

*Permanent address: Laboratoire d'lmmunogénétique, Université des Sciences et Techniques du Languedoc, 34060 Montpellier Cedex, France


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Immunol.Home page
K. A. Rogers, L. Jayashankar, F. Scinicariello, and R. Attanasio
Nonhuman Primate IgA: Genetic Heterogeneity and Interactions with CD89
J. Immunol., April 1, 2008; 180(7): 4816 - 4824.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.