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Nucleic Acids Research, 1984, Vol. 12, No. 3 1593-1608
© 1984


MOLECULAR BIOLOGY

The Bam repeats of the mouse genome belong in several superfamilies the longest of which is over 9 kb in size

Michèle Meunier-Rotival and Giorgio Bernardi

Laboratoire de Génétique Moléculaire, Institut Jacques Monod Tour 43, 2, Place Jussieu, 75005 Paris, France

Received November 29, 1983. Accepted January 12, 1984.

Mouse DNA contains two equally abundant, homologous subfamilies of MspI 3.6 and 5 kb repeated fragments. The first subfamily corresponds to the previously described (1) Bam 4 kb repeats, the second one to Bam repeated fragments of higher molecular weight. These subfamilies account for the vast majority of long Bam repeats and are linked with contiguous short Bam 0.5 kb repeats. A minority of these composite Bam repeats extend, on the 0.5 kb side, into R repeats. In turn, a fraction of the composite Bam/R repeats extend further, for at least 3 kb, into other repeated sequences contiguous to the R repeats. The long Bam repeats belong, therefore, in at least three super- families of repeats, the longest one being over 9 kb in size. Some general properties of these superfamilies are discussed.


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G Bernardi, B Olofsson, J Filipski, M Zerial, J Salinas, G Cuny, M Meunier-Rotival, and F Rodier
The mosaic genome of warm-blooded vertebrates
Science, May 24, 1985; 228(4702): 953 - 958.
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