Nucleic Acids Research, 1985, Vol. 13, No. 16 5927-5936
© 1985
Articles |
The primary structure of the DeoR represser from Escherichia coli K-12
Department of Molecular Biology, Odense University DK-5230 Odense M, Denmark 1Department of Microbiology, Wellcome Research Laboratories, Research Triangle Park NC, USA
*To whom reprint requests should be sent.
Received May 23, 1985. Revised August 5, 1985. Accepted August 5, 1985.
The nucleotide sequence of the deoR gene of E. coli, which codes for the DeoR repressor, has been determined. This gene codes for a polypeptide that is 252 amino acids residues in length. Computer-assisted analysis of the nucleotide sequence strongly suggests that the DNA binding domain of the DeoR repressor is located in the N-terminal part of the protein. After the coding region there is a dyad symmetry similar to a palindromic unit present outside many structural genes on the E. coli chromosome.
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