Skip Navigation

This Article
Right arrow Print PDF (2097K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (37)
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Limbach, K. J.
Right arrow Articles by Wu, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Limbach, K. J.
Right arrow Articles by Wu, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1985, Vol. 13, No. 2 631-644
© 1985

Articles

Characterization of two Drosophila melanogaster cylochrome c genes and their transcripts

Keith J. Limbach and Ray Wu

Section of Biochemistry, Molecular and Cell Biology, Cornell University Ithaca, NY 14253, USA

Received September 14, 1984. Revised December 17, 1984. Accepted December 17, 1984.

Analysis of total Drosophila melanogaster DNA by genomic blot hybridization indicates that two cytcchrome c-like sequences exist in the Drosophila genome. These two sequences, DC3 and DC4, have been isolated from a Charon 4A–D. melanogaster genomic library. DC3 and DC4 are located within a 4 kb region of DNA, at position 36A 10–11, on the left arm of chromosome 2. The nucleotide sequence of these two clones has been determined. Both DC3 and DC4 can encode functional cytochrome c proteins. The polypeptide sequences predicted by these two genes, however, differ at 32 amino acid residues. DC4 is expressed at varying, but relatively high levels throughout Drosophila development. In contrast, DC3 is expressed at constant, but relatively low levels throughout development.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
Z. Liu, H. Lin, S. Ye, Q.-y. Liu, Z. Meng, C.-m. Zhang, Y. Xia, E. Margoliash, Z. Rao, and X.-j. Liu
Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis
PNAS, June 13, 2006; 103(24): 8965 - 8970.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
L. Dorstyn, K. Mills, Y. Lazebnik, and S. Kumar
The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells
J. Cell Biol., November 8, 2004; 167(3): 405 - 410.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
H. Yu, N. M. Luscombe, H. X. Lu, X. Zhu, Y. Xia, J.-D. J. Han, N. Bertin, S. Chung, M. Vidal, and M. Gerstein
Annotation Transfer Between Genomes: Protein-Protein Interologs and Protein-DNA Regulogs
Genome Res., June 1, 2004; 14(6): 1107 - 1118.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
K. C. Zimmermann, J.-E. Ricci, N. M. Droin, and D. R. Green
The role of ARK in stress-induced apoptosis in Drosophila cells
J. Cell Biol., March 18, 2002; 156(6): 1077 - 1087.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
J. Varkey, P. Chen, R. Jemmerson, and J. M. Abrams
Altered Cytochrome c Display Precedes Apoptotic Cell Death in Drosophila
J. Cell Biol., February 22, 1999; 144(4): 701 - 710.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
V. M. Guzov, H. L. Houston, M. B. Murataliev, F. A. Walker, and R. Feyereisen
Molecular Cloning, Overexpression in Escherichia coli, Structural and Functional Characterization of House Fly Cytochrome b5
J. Biol. Chem., October 25, 1996; 271(43): 26637 - 26645.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.