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Nucleic Acids Research, 1986, Vol. 14, No. 1 205-216
© 1986

Articles

Data structures for DNA sequence manipulation

Charles B. Lawrence

Department of Cell Biology. Baylor College of Medicine One Baylor Plaza. Houston, TX 77030. USA

Received June 6, 1985. Two data structures designated Fragment and Construct are described. The Fragment data structure defines a continuous nucleic acid sequence from a unique genetic origin. The Construct defines a continuous sequence composed of sequences from multiple genetic origins. These data structures are manipulated by a set of software tools to simulate the construction of mosaic recombinant DNA molecules. They are also used as an interface between sequence data banks and analytical programs.


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