Skip Navigation

This Article
Right arrow Print PDF (4590K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by McDougall, J.
Right arrow Articles by Nazar, R. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McDougall, J.
Right arrow Articles by Nazar, R. N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1987, Vol. 15, No. 1 161-179
© 1987

Articles

Evolutionary changes in the higher order structure of the ribosomal 5S RNA

John McDougall and Ross N. Nazar

Department of Molecular Biology and Genetics, University of Guelph Guelph N1G 2W1, Canada

Received August 5, 1986. Revised December 1, 1986. Accepted December 1, 1986.

Comparative studies have been undertaken on the higher order structure of ribosomal 5S RNAs from diverse origins. Competitive reassociation studies show that 5S RNA from either a eukaryote or archaebacterium will form a stable ribonucleoprotein complex with the yeast ribosomal 5S RNA binding protein (YL3); in contrast, eubacterial RNAs will not compete in a similar fashion. Partial S1 ribonuclease digestion and ethylnitrosourea reactivity were used to probe the structural differences suggested by the reconstitution experiments. The results indicate a more compact higher order structure in eukaryotic 5S RNAs as compared to eubacteria and suggest that the archaebacterial 5S RNA contains features which are common to either group. The potential significance of these results with respect to a generalized model for the tertiary structure of the ribosomal 5S RNA and to the heterogeneity in the protein components of 5S RNA-protein complexes are discussed.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
Y. Lee and R. N. Nazar
Terminal Structure Mediates 5 S rRNA Stability and Integration during Ribosome Biogenesis
J. Biol. Chem., February 21, 2003; 278(9): 6635 - 6641.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Lee and R. N. Nazar
Ribosomal 5 S rRNA Maturation in Saccharomyces cerevisiae
J. Biol. Chem., June 13, 1997; 272(24): 15206 - 15212.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.