Nucleic Acids Research, 1987, Vol. 15, No. 1 181-198
© 1987
Articles |
The pro 
2(V) collagen gene is evolutionarily related to the major fibrillar-forming collagens
1Department of Microbiology and Immunology, Morse Institute of Molecular Genetics, SUNY-Health Science Center at Brooklyn, Box 44, 450 Clarkson Avenue Brooklyn, NY 11203, USA
Received July 31, 1986. Accepted November 17, 1986.
A number of overlapping cDNA clones, covering 5.2 kb of sequences which code for the human pro 
2(V) collagen chain, have been isolated. Analysis of the structural data have indicated a close evolutionary kinship between the pro 2(V) chain and the major fibrillar collagen types. Isolation and analysis of an 8 kb genomic fragment has further supported this notion by revealing a homologous arrangement of nine triple-helical domain exons. These studies have therefore provided conclusive evidence which categorizes the Type V collagen as a member of the Group 1 molecules, or fibrillar-forming collagens.
2Unite 12-INSERM, Hôpital des Enfantes Malades, Paris, France
3International Institute of Genetics and Biophysics, Naples, Italy
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  B. Gopalakrishnan, W.-M. Wang, and D. S. Greenspan Biosynthetic Processing of the Pro-{alpha}1(V)Pro-{alpha}2(V)Pro-{alpha}3(V) Procollagen Heterotrimer J. Biol. Chem., July 16, 2004; 279(29): 30904 - 30912. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Unsold, W. N. Pappano, Y. Imamura, B. M. Steiglitz, and D. S. Greenspan Biosynthetic Processing of the Pro-alpha 1(V)2Pro-alpha 2(V) Collagen Heterotrimer by Bone Morphogenetic Protein-1 and Furin-like Proprotein Convertases J. Biol. Chem., February 8, 2002; 277(7): 5596 - 5602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Imamura, I. C. Scott, and D. S. Greenspan The Pro-alpha 3(V) Collagen Chain. COMPLETE PRIMARY STRUCTURE, EXPRESSION DOMAINS IN ADULT AND DEVELOPING TISSUES, AND COMPARISON TO THE STRUCTURES AND EXPRESSION DOMAINS OF THE OTHER TYPES V AND XI PROCOLLAGEN CHAINS J. Biol. Chem., March 17, 2000; 275(12): 8749 - 8759. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Imamura, B. M. Steiglitz, and D. S. Greenspan Bone Morphogenetic Protein-1 Processes the NH2-terminal Propeptide, and a Furin-like Proprotein Convertase Processes the COOH-terminal Propeptide of pro-alpha 1(V) Collagen J. Biol. Chem., October 16, 1998; 273(42): 27511 - 27517. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. M. Vuoristo, T. Pihlajamaa, P. Vandenberg, D. J. Prockop, and L. Ala-Kokko The Human COL11A2 Gene Structure Indicates that the Gene Has Not Evolved with the Genes for the Major Fibrillar Collagens J. Biol. Chem., September 29, 1995; 270(39): 22873 - 22881. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Kessler, A. Fichard, H. Chanut-Delalande, M. Brusel, and F. Ruggiero Bone Morphogenetic Protein-1 (BMP-1) Mediates C-terminal Processing of Procollagen V Homotrimer J. Biol. Chem., July 13, 2001; 276(29): 27051 - 27057. [Abstract] [Full Text] [PDF]
|
|