Skip Navigation

This Article
Right arrow Print PDF (816K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (33)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Warmington, J. R.
Right arrow Articles by Oliver, S. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Warmington, J. R.
Right arrow Articles by Oliver, S. G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1987, Vol. 15, No. 21 8963-8982
© 1987

Articles

Polymorphisms on the right arm of yeast chromosome III associated with Ty transposition and recombination events

John R. Warmington, Rebecca P. Green*, Carol S. Newlon1 and Stephen G. Oliver

Department of Biochemistry and Applied Molecular Biology, University of Manchester Institute of Science and Technology PO Box 88, Manchester M60 1QD, UK 1Department of Microbiology, UMDNJ-New Jersey Medical School 185 South Orange Avenue, Newark, NJ 07103, USA

Received August 20, 1987. Revised October 8, 1987. Accepted October 8, 1987.

The region of Saccharomyces cerevisiae chromosome III centromere-distal to the PGK gene is the site of frequent chromosome polymorphisms. We have sequenced this region from fragments of chromosome III isolated from three different yeast strains, GRF88, CN31C and CF4-168. The sequence analysis demonstrates that these polymorphisms are associated with the presence of Ty and delta elements and defines a region of the chromosome which is a hot-spot for transposition events (the RAHS). The three strains can be arranged into a logical evolutionary series in which successive transposition and recombination events insert Ty elements and fuse them with consequent deletions of chromosome and of transposon sequences. The influence of such events on yeast genome evolution is discussed.

*Present address: Department of Biochemistry, Washington University School of Medicine, St. Louis, MO 63110, USA


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
Y. Shibata, A. Malhotra, S. Bekiranov, and A. Dutta
Yeast genome analysis identifies chromosomal translocation, gene conversion events and several sites of Ty element insertion
Nucleic Acids Res., October 1, 2009; 37(19): 6454 - 6465.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
L. C. Edwards-Ingram, M. E. Gent, D. C. Hoyle, A. Hayes, L. I. Stateva, and S. G. Oliver
Comparative Genomic Hybridization Provides New Insights Into the Molecular Taxonomy of the Saccharomyces Sensu Stricto Complex
Genome Res., June 1, 2004; 14(6): 1043 - 1051.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S. Casaregola, C. Neuveglise, E. Bon, and C. Gaillardin
Ylli, a Non-LTR Retrotransposon L1 Family in the Dimorphic Yeast Yarrowia lipolytica
Mol. Biol. Evol., May 1, 2002; 19(5): 664 - 677.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
K. Umezu, M. Hiraoka, M. Mori, and H. Maki
Structural Analysis of Aberrant Chromosomes That Occur Spontaneously in Diploid Saccharomyces cerevisiae: Retrotransposon Ty1 Plays a Crucial Role in Chromosomal Rearrangements
Genetics, January 1, 2002; 160(1): 97 - 110.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
A. Goffeau, B. G. Barrell, H. Bussey, R. W. Davis, B. Dujon, H. Feldmann, F. Galibert, J. D. Hoheisel, C. Jacq, M. Johnston, et al.
Life with 6000 Genes
Science, October 25, 1996; 274(5287): 546 - 567.
[Abstract] [Full Text]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.