Nucleic Acids Research, 1987, Vol. 15, No. 4 1353-1361
© 1987
Articles |
Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates
Department of Molecular Biology, Vanderbilt University Nashville, TN 37235, USA
Received January 14, 1987. Accepted January 23, 1987.
The previously presented consensus sequence for eukaryotic translation initiation sites by Kozak (1) was derived substantially from vertebrate mRNA sequences. Drosophila nuclear genes exhibit a significantly different translation start consensus sequence. These differences probably do not represent mechanistic differences in translation initiation inasmuch as both taxa exhibit identical preferences and restrictions at the crucial -3 position. Using more conservative criteria for the assignment of consensus the following consensus sequences were derived: vertebrate--CANCAUG and Drosophila--CANCAUG
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L. McNeil, M. Chinkers, and M. Forte Identification, Characterization, and Developmental Regulation of a Receptor Guanylyl Cyclase Expressed during Early Stages of Drosophila Development J. Biol. Chem., March 31, 1995; 270(13): 7189 - 7196. [Abstract] [Full Text] [PDF]
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Y. Ruan, C. Chen, Y. Cao, and R. S. Garofalo The Drosophila Insulin Receptor Contains a Novel Carboxyl-terminal Extension Likely to Play an Important Role in Signal Transduction J. Biol. Chem., March 3, 1995; 270(9): 4236 - 4243. [Abstract] [Full Text] [PDF]
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M. Andjelkovic, P. F. Jones, U. Grossniklaus, P. Cron, A. F. Schier, M. Dick, G. Bilbe, and B. A. Hemmings Developmental Regulation of Expression and Activity of Multiple Forms of the Drosophila RAC Protein Kinase J. Biol. Chem., February 24, 1995; 270(8): 4066 - 4075. [Abstract] [Full Text] [PDF]
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B Murugasu-Oei, V Rodrigues, X Yang, and W Chia Masquerade: a novel secreted serine protease-like molecule is required for somatic muscle attachment in the Drosophila embryo. Genes & Dev., January 15, 1995; 9(2): 139 - 154. [Abstract] [PDF]
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W. Whitfield, M. Chaplin, K Oegema, H Parry, and D. Glover The 190 kDa centrosome-associated protein of Drosophila melanogaster contains four zinc finger motifs and binds to specific sites on polytene chromosomes J. Cell Sci., January 11, 1995; 108(11): 3377 - 3387. [Abstract] [PDF]
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F. Markussen, A. Michon, W Breitwieser, and A Ephrussi Translational control of oskar generates short OSK, the isoform that induces pole plasma assembly Development, January 11, 1995; 121(11): 3723 - 3732. [Abstract] [PDF]
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J. Heuer, K Li, and T. Kaufman The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis Development, January 11, 1995; 121(11): 3861 - 3876. [Abstract] [PDF]
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C. Eberhart and S. Wasserman The pelota locus encodes a protein required for meiotic cell division: an analysis of G2/M arrest in Drosophila spermatogenesis Development, January 10, 1995; 121(10): 3477 - 3486. [Abstract] [PDF]
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C Rongo, E. Gavis, and R Lehmann Localization of oskar RNA regulates oskar translation and requires Oskar protein Development, January 9, 1995; 121(9): 2737 - 2746. [Abstract] [PDF]
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M G Anderson, G L Perkins, P Chittick, R J Shrigley, and W A Johnson drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia. Genes & Dev., January 1, 1995; 9(1): 123 - 137. [Abstract] [PDF]
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Y Graba, K Gieseler, D Aragnol, P Laurenti, M. Mariol, H Berenger, T Sagnier, and J Pradel DWnt-4, a novel Drosophila Wnt gene acts downstream of homeotic complex genes in the visceral mesoderm Development, January 1, 1995; 121(1): 209 - 218. [Abstract] [PDF]
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K Arora, M S Levine, and M B O'Connor The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo. Genes & Dev., November 1, 1994; 8(21): 2588 - 2601. [Abstract] [PDF]
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V Francois, M Solloway, J W O'Neill, J Emery, and E Bier Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes & Dev., November 1, 1994; 8(21): 2602 - 2616. [Abstract] [PDF]
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A Kispert, B G Herrmann, M Leptin, and R Reuter Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. Genes & Dev., September 15, 1994; 8(18): 2137 - 2150. [Abstract] [PDF]
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A. Lonie, R. D'Andrea, R. Paro, and R. Saint Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression Development, September 1, 1994; 120(9): 2629 - 2636. [Abstract] [PDF]
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J Wang and L R Bell The Sex-lethal amino terminus mediates cooperative interactions in RNA binding and is essential for splicing regulation. Genes & Dev., September 1, 1994; 8(17): 2072 - 2085. [Abstract] [PDF]
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R Quiring, U Walldorf, U Kloter, and W. Gehring Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans Science, August 5, 1994; 265(5173): 785 - 789. [Abstract] [PDF]
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