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Nucleic Acids Research, 1987, Vol. 15, No. 4 1799-1806
© 1987

Articles

The nucleotide sequence of the tnpA gene of Tn21

E. Ward and J. Grinsted

Department of Microbiology and Unit of Molecular Genetics, University of Bristol Bristol BS8 LTD. UK

Received December 4, 1986. Accepted January 28, 1987.

The nucleotide sequence of the tnpA gene of Tn21 is presented. The traneposase encoded by this gene is exactly the same length (988 amino acids) as the Tn501 transposase (4). and shows 72% homology overall with this protein, with greater homology towards the C-terminus. The sequence of the transposase is discussed in the context of the evolution of Class II transposable elements and of the characteristics of the enzyme's action.


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Transposon Tn21, Flagship of the Floating Genome
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