Skip Navigation

This Article
Right arrow Print PDF (1103K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Duchêne, M.
Right arrow Articles by Domdey, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Duchêne, M.
Right arrow Articles by Domdey, H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1988, Vol. 16, No. 15 7233-7239
© 1988

Articles

Molecular consequences of truncations of the first exon for in vitro splicing of yeast actin pre-mRNA

Michael Duchêne, Angela Löw, Andrea Schweizer and Horst Domdey*

Laboratonum für Molekulare Biologie, Genzentrum-der-Ludwig-Maximilians-Universität München, D-8033 Martinsried, FRG

*To whom correspondence should be addressed

Received June 14, 1988. Accepted July 11, 1988.

A defined minimum length of the first exon is required for the generation of spliced products from a synthetic yeast actin mRNA-precursor in vitro. If the first exon is 1, 2, 3 or 5 nucleotides long, only the first step of the splicing reaction can take place. A transcript starting with the first nucleotide of the intron does not get converted into any of the normally obtained splicing products or intermediates. On the other hand, spliceosome assembly does not depend on the presence of a first exon.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Genes Dev.Home page
V. L. Reichert, H. Le Hir, M. S. Jurica, and M. J. Moore
5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly
Genes & Dev., November 1, 2002; 16(21): 2778 - 2791.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.