Nucleic Acids Research, 1988, Vol. 16, No. 3 1043-1061
© 1988
Articles |
Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells
Department of Cellular and Developmental Biology, Harvard University Cambridge, MA 02138, USA
*To whom reprint requests should be sent
Received September 14, 1987. Revised December 29, 1987. Accepted December 29, 1987.
The promoter from the metallothiortein gene may be a useful conditional promoter for the construction of chimeric genes to be expressed in Drosophila cells in culture. To explore this possibility the responses of the endogenous metallothionein gene and an in vitro constructed chimeric gene containing the metallothiortein promoter were examined. Copper and cadmium, when added to the growth medium of Drosophila Schneider's line 2 cells, can produce a 30–100 fold induction of metallothionein mRNA levels. The level of induction depends on the amount of copper or cadmium added to the medium and these mRNA levels remain high for at least four days. Copper is less toxic than cadmium and does not induce a typical heat-shock response in the cells. Finally, a chimeric gene containing the metallothionein promoter shows a similar induction when transformed into the cells.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  L. Bugga, A. Ratnaparkhi, and K. Zinn The Cell Surface Receptor Tartan Is a Potential In Vivo Substrate for the Receptor Tyrosine Phosphatase Ptp52F Mol. Cell. Biol., June 15, 2009; 29(12): 3390 - 3400. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Cairrao, A. S. Halees, K. S. A. Khabar, D. Morello, and N. Vanzo AU-Rich Elements Regulate Drosophila Gene Expression Mol. Cell. Biol., May 15, 2009; 29(10): 2636 - 2643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Katzenberger, M. S. Marengo, and D. A. Wassarman Control of Alternative Splicing by Signal-dependent Degradation of Splicing-regulatory Proteins J. Biol. Chem., April 17, 2009; 284(16): 10737 - 10746. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Akbar, S. Ray, and H. Kramer The SM Protein Car/Vps33A Regulates SNARE-mediated Trafficking to Lysosomes and Lysosome-related Organelles Mol. Biol. Cell, March 15, 2009; 20(6): 1705 - 1714. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. S. Kocherlakota, J.-m. Wu, J. McDermott, and S. M. Abmayr Analysis of the Cell Adhesion Molecule Sticks-and-Stones Reveals Multiple Redundant Functional Domains, Protein-Interaction Motifs and Phosphorylated Tyrosines That Direct Myoblast Fusion in Drosophila melanogaster Genetics, March 1, 2008; 178(3): 1371 - 1383. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Ng, O. Koechlin, M. Ramalho, D. Raman, and N. Krauzewicz Extracellular self-assembly of virus-like particles from secreted recombinant polyoma virus major coat protein Protein Eng. Des. Sel., December 1, 2007; 20(12): 591 - 598. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Rohrbough, E. Rushton, E. Woodruff III, T. Fergestad, K. Vigneswaran, and K. Broadie Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation Genes & Dev., October 15, 2007; 21(20): 2607 - 2628. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. C. Baker and M. T. Fuller Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog Development, August 1, 2007; 134(15): 2863 - 2869. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Cherbas and P. Cherbas Drosophila Cell Culture and Transformation CSH Protocols, July 1, 2007; 2007(16): pdb.top6 - pdb.top6. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Matsushima and L. S. Kaguni Differential Phenotypes of Active Site and Human Autosomal Dominant Progressive External Ophthalmoplegia Mutations in Drosophila Mitochondrial DNA Helicase Expressed in Schneider Cells J. Biol. Chem., March 30, 2007; 282(13): 9436 - 9444. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Katzenberger, M. S. Marengo, and D. A. Wassarman ATM and ATR Pathways Signal Alternative Splicing of Drosophila TAF1 Pre-mRNA in Response to DNA Damage Mol. Cell. Biol., December 15, 2006; 26(24): 9256 - 9267. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Balagopalan, M.-H. Chen, E. R. Geisbrecht, and S. M. Abmayr The CDM Superfamily Protein MBC Directs Myoblast Fusion through a Mechanism That Requires Phosphatidylinositol 3,4,5-Triphosphate Binding but Is Independent of Direct Interaction with DCrk Mol. Cell. Biol., December 15, 2006; 26(24): 9442 - 9455. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. M. Siegers, J. Yang, C. U. Duerr, P. J. Nielsen, M. Reth, and W. W. A. Schamel Identification of disulfide bonds in the Ig-{alpha}/Ig-{beta} component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system Int. Immunol., September 1, 2006; 18(9): 1385 - 1396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Parra-Lopez, J. M. Calvo-Calle, T. O. Cameron, L. E. Vargas, L. M. Salazar, M. E. Patarroyo, E. Nardin, and L. J. Stern Major Histocompatibility Complex and T Cell Interactions of a Universal T Cell Epitope from Plasmodium falciparum Circumsporozoite Protein J. Biol. Chem., May 26, 2006; 281(21): 14907 - 14917. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 U. Acharya, M. B. Edwards, R. A. Jorquera, H. Silva, K. Nagashima, P. Labarca, and J. K. Acharya Drosophila melanogaster Scramblases modulate synaptic transmission. J. Cell Biol., April 10, 2006; 173(1): 69 - 82. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Luo, K. Koles, W. Vorndam, R. S. Haltiwanger, and V. M. Panin Protein O-Fucosyltransferase 2 Adds O-Fucose to Thrombospondin Type 1 Repeats J. Biol. Chem., April 7, 2006; 281(14): 9393 - 9399. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Egli, H. Yepiskoposyan, A. Selvaraj, K. Balamurugan, R. Rajaram, A. Simons, G. Multhaup, S. Mettler, A. Vardanyan, O. Georgiev, et al. A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification. Mol. Cell. Biol., March 1, 2006; 26(6): 2286 - 2296. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Guelman, T. Suganuma, L. Florens, S. K. Swanson, C. L. Kiesecker, T. Kusch, S. Anderson, J. R. Yates III, M. P. Washburn, S. M. Abmayr, et al. Host Cell Factor and an Uncharacterized SANT Domain Protein Are Stable Components of ATAC, a Novel dAda2A/dGcn5-Containing Histone Acetyltransferase Complex in Drosophila Mol. Cell. Biol., February 1, 2006; 26(3): 871 - 882. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Dzhambazov, K. S. Nandakumar, J. Kihlberg, L. Fugger, R. Holmdahl, and M. Vestberg Therapeutic Vaccination of Active Arthritis with a Glycosylated Collagen Type II Peptide in Complex with MHC Class II Molecules J. Immunol., February 1, 2006; 176(3): 1525 - 1533. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Lyalin, K. Koles, S. D. Roosendaal, E. Repnikova, L. Van Wechel, and V. M. Panin The twisted Gene Encodes Drosophila Protein O-Mannosyltransferase 2 and Genetically Interacts With the rotated abdomen Gene Encoding Drosophila Protein O-Mannosyltransferase 1 Genetics, January 1, 2006; 172(1): 343 - 353. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Nagel, A. Krejci, G. Tenin, A. Bravo-Patino, S. Bray, D. Maier, and A. Preiss Hairless-Mediated Repression of Notch Target Genes Requires the Combined Activity of Groucho and CtBP Corepressors Mol. Cell. Biol., December 1, 2005; 25(23): 10433 - 10441. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Pulipparacharuvil, M. A. Akbar, S. Ray, E. A. Sevrioukov, A. S. Haberman, J. Rohrer, and H. Kramer Drosophila Vps16A is required for trafficking to lysosomes and biogenesis of pigment granules J. Cell Sci., August 15, 2005; 118(16): 3663 - 3673. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Liu, M. S. Williamson, S. J. Lansdell, I. Denholm, Z. Han, and N. S. Millar From The Cover: A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens (brown planthopper) PNAS, June 14, 2005; 102(24): 8420 - 8425. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. M. Kampmueller and D. J. Miller The Cellular Chaperone Heat Shock Protein 90 Facilitates Flock House Virus RNA Replication in Drosophila Cells J. Virol., June 1, 2005; 79(11): 6827 - 6837. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Serpe, A. Ralston, S. S. Blair, and M. B. O'Connor Matching catalytic activity to developmental function: Tolloid-related processes Sog in order to help specify the posterior crossvein in the Drosophila wing Development, June 1, 2005; 132(11): 2645 - 2656. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. A. Sevrioukov, N. Moghrabi, M. Kuhn, and H. Kramer A Mutation in dVps28 Reveals a Link between a Subunit of the Endosomal Sorting Complex Required for Transport-I Complex and the Actin Cytoskeleton in Drosophila Mol. Biol. Cell, May 1, 2005; 16(5): 2301 - 2312. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Matsushima, C. Adan, R. Garesse, and L. S. Kaguni Drosophila Mitochondrial Transcription Factor B1 Modulates Mitochondrial Translation but Not Transcription or DNA Copy Number in Schneider Cells J. Biol. Chem., April 29, 2005; 280(17): 16815 - 16820. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. I. ORBAN and E. IZAURRALDE Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome RNA, April 1, 2005; 11(4): 459 - 469. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Yokokura, D. Dresnek, N. Huseinovic, S. Lisi, E. Abdelwahid, P. Bangs, and K. White Dissection of DIAP1 Functional Domains via a Mutant Replacement Strategy J. Biol. Chem., December 10, 2004; 279(50): 52603 - 52612. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Matsushima, R. Garesse, and L. S. Kaguni Drosophila Mitochondrial Transcription Factor B2 Regulates Mitochondrial DNA Copy Number and Transcription in Schneider Cells J. Biol. Chem., June 25, 2004; 279(26): 26900 - 26905. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. L. Farr, Y. Matsushima, A. T. Lagina III, N. Luo, and L. S. Kaguni Physiological and Biochemical Defects in Functional Interactions of Mitochondrial DNA Polymerase and DNA-binding Mutants of Single-stranded DNA-binding Protein J. Biol. Chem., April 23, 2004; 279(17): 17047 - 17053. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Islam, L. V. Kristiansen, S. Romani, L. Garcia-Alonso, and M. Hortsch Activation of EGF Receptor Kinase by L1-mediated Homophilic Cell Interactions Mol. Biol. Cell, April 1, 2004; 15(4): 2003 - 2012. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. R. Leach and D. B. Williams Lectin-deficient Calnexin Is Capable of Binding Class I Histocompatibility Molecules in Vivo and Preventing Their Degradation J. Biol. Chem., March 5, 2004; 279(10): 9072 - 9079. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Koles, K. D. Irvine, and V. M. Panin Functional Characterization of Drosophila Sialyltransferase J. Biol. Chem., February 6, 2004; 279(6): 4346 - 4357. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Chyb, A. Dahanukar, A. Wickens, and J. R. Carlson Drosophila Gr5a encodes a taste receptor tuned to trehalose PNAS, November 25, 2003; 100(suppl_2): 14526 - 14530. [Abstract] [Full Text]
|
|
|
|
|
|
W. W. A. Schamel, S. Kuppig, B. Becker, K. Gimborn, H.-P. Hauri, and M. Reth A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum PNAS, August 19, 2003; 100(17): 9861 - 9866. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Ilangovan, W. L. Marshall, Y. Hua, and J. Zhou Inhibition of Apoptosis by Z-VAD-fmk in SMN-depleted S2 Cells J. Biol. Chem., August 15, 2003; 278(33): 30993 - 30999. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. C. Liebl, R. G. Rowe, D. J. Forsthoefel, A. L. Stammler, E. R. Schmidt, M. Turski, and M. A. Seeger Interactions between the secreted protein Amalgam, its transmembrane receptor Neurotactin and the Abelson tyrosine kinase affect axon pathfinding Development, July 15, 2003; 130(14): 3217 - 3226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Faure, D. F. Barber, S. M. Takahashi, T. Jin, and E. O. Long Spontaneous Clustering and Tyrosine Phosphorylation of NK Cell Inhibitory Receptor Induced by Ligand Binding J. Immunol., June 15, 2003; 170(12): 6107 - 6114. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Islam, S.-Y. Wei, W.-H. Chiu, M. Hortsch, and J.-C. Hsu Neuroglian activates Echinoid to antagonize the Drosophila EGF receptor signaling pathway Development, May 15, 2003; 130(10): 2051 - 2059. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. S. Mani, R. Rajagopal, A. B. Garfinkel, X. Fan, and M. F. Wolfner A hydrophilic lamin-binding domain from the Drosophila YA protein can target proteins to the nuclear envelope J. Cell Sci., May 15, 2003; 116(10): 2067 - 2072. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Chang and D. Morisato Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo Development, March 14, 2003; 129(24): 5635 - 5645. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Pacquelet, L. Lin, and P. Rorth Binding site for p120/{delta}-catenin is not required for Drosophila E-cadherin function in vivo J. Cell Biol., February 3, 2003; 160(3): 313 - 319. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. F. Barber and E. O. Long Coexpression of CD58 or CD48 with Intercellular Adhesion Molecule 1 on Target Cells Enhances Adhesion of Resting NK Cells J. Immunol., January 1, 2003; 170(1): 294 - 299. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Mishra-Gorur, M. D. Rand, B. Perez-Villamil, and S. Artavanis-Tsakonas Down-regulation of Delta by proteolytic processing J. Cell Biol., October 28, 2002; 159(2): 313 - 324. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D.-H. Huang, Y.-L. Chang, C.-C. Yang, I-C. Pan, and B. King pipsqueak Encodes a Factor Essential for Sequence-Specific Targeting of a Polycomb Group Protein Complex Mol. Cell. Biol., September 1, 2002; 22(17): 6261 - 6271. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. M. Panin, L. Shao, L. Lei, D. J. Moloney, K. D. Irvine, and R. S. Haltiwanger Notch Ligands Are Substrates for Protein O-Fucosyltransferase-1 and Fringe J. Biol. Chem., August 9, 2002; 277(33): 29945 - 29952. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Malhotra, M. C. Koopmann, K. A. Kazen-Gillespie, N. Fettman, M. Hortsch, and L. L. Isom Structural Requirements for Interaction of Sodium Channel beta 1 Subunits with Ankyrin J. Biol. Chem., July 12, 2002; 277(29): 26681 - 26688. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. S. Patil, A. Pashine, M. P. Belmares, W. Liu, B. Kaneshiro, J. Rabinowitz, H. McConnell, and E. D. Mellins Rheumatoid Arthritis (RA)-Associated HLA-DR Alleles Form Less Stable Complexes with Class II-Associated Invariant Chain Peptide Than Non-RA-Associated HLA-DR Alleles J. Immunol., December 15, 2001; 167(12): 7157 - 7168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. A. Dworak, M. A. Charles, L. B. Pellerano, and H. Sink Characterization of Drosophila hibris, a gene related to human nephrin Development, November 1, 2001; 128(21): 4265 - 4276. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Zhang, D. Egli, O. Georgiev, and W. Schaffner The Drosophila Homolog of Mammalian Zinc Finger Factor MTF-1 Activates Transcription in Response to Heavy Metals Mol. Cell. Biol., July 15, 2001; 21(14): 4505 - 4514. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. K. LeMosy, Y.-Q. Tan, and C. Hashimoto Activation of a protease cascade involved in patterning the Drosophila embryo PNAS, April 5, 2001; (2001) 81026598. [Abstract] [Full Text]
|
|
|
|
|
|
J.-H. Han, S. H. Lee, Y.-Q. Tan, E. K. LeMosy, and C. Hashimoto Gastrulation Defective is a serine protease involved in activating the receptor Toll to polarize the Drosophila embryo PNAS, August 1, 2000; 97(16): 9093 - 9097. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Wilson, M. J. Powell, S. E. Hoover, and P. Sarnow Naturally Occurring Dicistronic Cricket Paralysis Virus RNA Is Regulated by Two Internal Ribosome Entry Sites Mol. Cell. Biol., July 15, 2000; 20(14): 4990 - 4999. [Abstract] [Full Text]
|
|
|
|
|
|
K. Yu, S. Srinivasan, O. Shimmi, B. Biehs, K. E. Rashka, D. Kimelman, M. B. O'Connor, and E. Bier Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity Development, May 15, 2000; 127(10): 2143 - 2154. [Abstract] [PDF]
|
|
|
|
 |
|
 M. C. Holmes and R. Tjian Promoter-Selective Properties of the TBP-Related Factor TRF1 Science, May 5, 2000; 288(5467): 867 - 870. [Abstract] [Full Text]
|
|
|
|
|
|
U. G. Danilczyk, M. F. Cohen-Doyle, and D. B. Williams Functional Relationship between Calreticulin, Calnexin, and the Endoplasmic Reticulum Luminal Domain of Calnexin J. Biol. Chem., April 21, 2000; 275(17): 13089 - 13097. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Malhotra, K. Kazen-Gillespie, M. Hortsch, and L. L. Isom Sodium Channel beta Subunits Mediate Homophilic Cell Adhesion and Recruit Ankyrin to Points of Cell-Cell Contact J. Biol. Chem., April 6, 2000; 275(15): 11383 - 11388. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-h. Jin, K. Sawamoto, M. Ito, and H. Okano The Interaction between the Drosophila Secreted Protein Argos and the Epidermal Growth Factor Receptor Inhibits Dimerization of the Receptor and Binding of Secreted Spitz to the Receptor Mol. Cell. Biol., March 15, 2000; 20(6): 2098 - 2107. [Abstract] [Full Text]
|
|
|
|
|
|
P. A. Colussi, L. M. Quinn, D. C.S. Huang, M. Coombe, S. H. Read, H. Richardson, and S. Kumar Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery J. Cell Biol., February 21, 2000; 148(4): 703 - 714. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Lehembre, P. Badenhorst, S. Müller, A. Travers, F. Schweisguth, and A. Dejean Covalent Modification of the Transcriptional Repressor Tramtrack by the Ubiquitin-Related Protein Smt3 in Drosophila Flies Mol. Cell. Biol., February 1, 2000; 20(3): 1072 - 1082. [Abstract] [Full Text]
|
|
|
|
|
|
H. Appel, L. Gauthier, J. Pyrdol, and K. W. Wucherpfennig Kinetics of T-cell Receptor Binding by Bivalent HLA-DR{middle dot}Peptide Complexes That Activate Antigen-specific Human T-cells J. Biol. Chem., January 7, 2000; 275(1): 312 - 321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. McCartney, R. Kulikauskas, D. LaJeunesse, and R. Fehon The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation Development, January 3, 2000; 127(6): 1315 - 1324. [Abstract] [PDF]
|
|
|
|
 |
|
 O. V. Naidenko, J. K. Maher, W. A. Ernst, T. Sakai, R. L. Modlin, and M. Kronenberg Binding and Antigen Presentation of Ceramide-Containing Glycolipids by Soluble Mouse and Human Cd1d Molecules J. Exp. Med., October 18, 1999; 190(8): 1069 - 1080. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Abbaszade, R.-Q. Liu, F. Yang, S. A. Rosenfeld, O. H. Ross, J. R. Link, D. M. Ellis, M. D. Tortorella, M. A. Pratta, J. M. Hollis, et al. Cloning and Characterization of ADAMTS11, an Aggrecanase from the ADAMTS Family J. Biol. Chem., August 13, 1999; 274(33): 23443 - 23450. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. S. Han and Y. T. Ip Interaction and Specificity of Rel-related Proteins in Regulating Drosophila Immunity Gene Expression J. Biol. Chem., July 23, 1999; 274(30): 21355 - 21361. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. H.F. Hausmann, B. Yu, S. Hausmann, and K. W. Wucherpfennig pH-dependent Peptide Binding Properties of the Type I Diabetes-associated I-Ag7 Molecule: Rapid Release of CLIP at an Endosomal pH J. Exp. Med., June 7, 1999; 189(11): 1723 - 1734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Tortorella, T. C. Burn, M. A. Pratta, I. Abbaszade, J. M. Hollis, R. Liu, S. A. Rosenfeld, R. A. Copeland, C. P. Decicco, R. Wynn, et al. Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of Proteins Science, June 4, 1999; 284(5420): 1664 - 1666. [Abstract] [Full Text]
|
|
|
|
|
|
L. Salter-Cid, A. Brunmark, Y. Li, D. Leturcq, P. A. Peterson, M. R. Jackson, and Y. Yang Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: Implications for cellular iron homeostasis PNAS, May 11, 1999; 96(10): 5434 - 5439. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Varkey, P. Chen, R. Jemmerson, and J. M. Abrams Altered Cytochrome c Display Precedes Apoptotic Cell Death in Drosophila J. Cell Biol., February 22, 1999; 144(4): 701 - 710. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Pistis, D. Belelli, K. McGurk, J. A Peters, and J. J Lambert Complementary regulation of anaesthetic activation of human ({alpha}6{beta}3{gamma}2L) and Drosophila (RDL) GABA receptors by a single amino acid residue J. Physiol., February 15, 1999; 515(1): 3 - 18. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Malhotra, P. Tsiotra, D. Karagogeos, and M. Hortsch Cis-activation of L1-mediated Ankyrin Recruitment by TAG-1 Homophilic Cell Adhesion J. Biol. Chem., December 11, 1998; 273(50): 33354 - 33359. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Di Fruscio, T. Chen, S. Bonyadi, P. Lasko, and S. Richard The Identification of Two Drosophila K Homology Domain Proteins. KEP1 AND SAM ARE MEMBERS OF THE Sam68 FAMILY OF GSG DOMAIN PROTEINS J. Biol. Chem., November 13, 1998; 273(46): 30122 - 30130. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Kurepa, C. A. Hasemann, and J. Forman Qa-1b Binds Conserved Class I Leader Peptides Derived from Several Mammalian Species J. Exp. Med., September 7, 1998; 188(5): 973 - 978. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Schaniel, E. Pardali, F. Sallusto, M. Speletas, C. Ruedl, T. Shimizu, T. Seidl, J. Andersson, F. Melchers, A. G. Rolink, et al. Activated Murine B Lymphocytes and Dendritic Cells Produce a Novel CC Chemokine which Acts Selectively on Activated T Cells J. Exp. Med., August 3, 1998; 188(3): 451 - 463. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. W. Graner, T. A. Bunch, S. Baumgartner, A. Kerschen, and D. L. Brower Splice Variants of the Drosophila PS2 Integrins Differentially Interact with RGD-containing Fragments of the Extracellular Proteins Tiggrin, Ten-m, and D-Laminin alpha 2 J. Biol. Chem., July 17, 1998; 273(29): 18235 - 18241. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Klueg, T. R. Parody, and M. A.T. Muskavitch Complex Proteolytic Processing Acts on Delta, a Transmembrane Ligand for Notch, during Drosophila Development Mol. Biol. Cell, July 1, 1998; 9(7): 1709 - 1723. [Abstract] [Full Text]
|
|
|
|
|
|
M. Ulbrecht, S. Modrow, R. Srivastava, P. A. Peterson, and E. H. Weiss Interaction of HLA-E with Peptides and the Peptide Transporter In Vitro: Implications for its Function in Antigen Presentation J. Immunol., May 1, 1998; 160(9): 4375 - 4385. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Howes, J. D. Wasserman, and M. Freeman In Vivo Analysis of Argos Structure-Function. SEQUENCE REQUIREMENTS FOR INHIBITION OF THE DROSOPHILA EPIDERMAL GROWTH FACTOR RECEPTOR J. Biol. Chem., February 13, 1998; 273(7): 4275 - 4281. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Aichinger, L. Karlsson, M. R. Jackson, M. Vestberg, J. H. Vaughan, L. Teyton, R. I. Lechler, and P. A. Peterson Major Histocompatibility Complex Class II-dependent Unfolding, Transport, and Degradation of Endogenous Proteins J. Biol. Chem., November 14, 1997; 272(46): 29127 - 29136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kondo, T. Yokokura, and S. Nagata Activation of distinct caspase-like proteases by Fas and reaper in Drosophila cells PNAS, October 28, 1997; 94(22): 11951 - 11956. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Nguyen and T. C. Sudhof Binding Properties of Neuroligin 1 and Neurexin 1beta Reveal Function as Heterophilic Cell Adhesion Molecules J. Biol. Chem., October 10, 1997; 272(41): 26032 - 26039. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Von Ohlen, D. Lessing, R. Nusse, and J. E. Hooper Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein PNAS, March 18, 1997; 94(6): 2404 - 2409. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Kreft, D. Berndorff, A. Bottinger, S. Finnemann, D. Wedlich, M. Hortsch, R. Tauber, and R. Gessner LI-Cadherin-mediated Cell-Cell Adhesion Does Not Require Cytoplasmic Interactions J. Cell Biol., March 10, 1997; 136(5): 1109 - 1121. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Butler, S Ray, and Y Hiromi klingon, a novel member of the Drosophila immunoglobulin superfamily, is required for the development of the R7 photoreceptor neuron Development, January 2, 1997; 124(4): 781 - 792. [Abstract] [PDF]
|
|
|
|
|
|
P. Chen, P. Lee, L. Otto, and J. Abrams Apoptotic Activity of REAPER Is Distinct from Signaling by the Tumor Necrosis Factor Receptor 1Death Domain J. Biol. Chem., October 18, 1996; 271(42): 25735 - 25737. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P Chen, W Nordstrom, B Gish, and J M Abrams grim, a novel cell death gene in Drosophila. Genes & Dev., July 15, 1996; 10(14): 1773 - 1782. [Abstract] [PDF]
|
|
|
|
|
|
S D Zhang, J Kassis, B Olde, D M Mellerick, and W F Odenwald Pollux, a novel Drosophila adhesion molecule, belongs to a family of proteins expressed in plants, yeast, nematodes, and man. Genes & Dev., May 1, 1996; 10(9): 1108 - 1119. [Abstract] [PDF]
|
|
|
|
|
|
M Tiemeyer and C. Goodman Gliolectin is a novel carbohydrate-binding protein expressed by a subset of glia in the embryonic Drosophila nervous system Development, January 3, 1996; 122(3): 925 - 936. [Abstract] [PDF]
|
|
|
|
|
|
M. R. Tota, L. Xu, A. Sirotina, C. D. Strader, and M. P. Graziano Interaction of [fluorescein-Trp[IMAGE]]Glucagon with the Human Glucagon Receptor Expressed in Drosophila Schneider 2 Cells J. Biol. Chem., November 3, 1995; 270(44): 26466 - 26472. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hortsch, Y.-m. E. Wang, Y. Marikar, and A. J. Bieber The Cytoplasmic Domain of the Drosophila Cell Adhesion Molecule Neuroglian Is Not Essential for Its Homophilic Adhesive Properties in S2 Cells J. Biol. Chem., August 11, 1995; 270(32): 18809 - 18817. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R Schweitzer, M Shaharabany, R Seger, and B Z Shilo Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes & Dev., June 15, 1995; 9(12): 1518 - 1529. [Abstract] [PDF]
|
|
|
|
|
|
E Eldon, S Kooyer, D D'Evelyn, M Duman, P Lawinger, J Botas, and H Bellen The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll Development, January 4, 1994; 120(4): 885 - 899. [Abstract] [PDF]
|
|
|
|
|
|
S. Speicher, U Thomas, U Hinz, and E Knust The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation Development, January 3, 1994; 120(3): 535 - 544. [Abstract] [PDF]
|
|
|
|
|
|
R. Fehon, I. Dawson, and S Artavanis-Tsakonas A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene Development, January 3, 1994; 120(3): 545 - 557. [Abstract] [PDF]
|
|
|
|
|
|
B Jones and W McGinnis The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function. Genes & Dev., February 1, 1993; 7(2): 229 - 240. [Abstract] [PDF]
|
|
|
|
|
|
J Colgan and J L Manley TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters. Genes & Dev., February 1, 1992; 6(2): 304 - 315. [Abstract] [PDF]
|
|
|
|
|
|
D Smoller, C Friedel, A Schmid, D Bettler, L Lam, and B Yedvobnick The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers. Genes & Dev., October 1, 1990; 4(10): 1688 - 1700. [Abstract] [PDF]
|
|