Nucleic Acids Research, 1989, Vol. 17, No. 13 4917-4924
© 1989
MOLECULAR BIOLOGY |
An ARS/silencer binding factor also activates two ribosomal protein genes in yeast
Section for Molecular Biology, Department of Molecular Cell Biology, University of Amsterdam Amsterdam, The Netherlands 1Laboratory of Biochemistry, Vrije Universiteit Amsterdam, The Netherlands
Received May 21, 1989. Accepted June 7, 1989.
GFI is an abundant yeast DNA-binding protein, capable of binding to both ARS sequences and to the upstream regions of a number of nuclear genes coding for mitochondria] proteins (Dorsman et al., Nucl. Acids Res., 16 [1988] 72877301). GFI binding sites conform to the consensus RTCRYN5ACG, an element also present in the binding sites of factors designated SUF and TAF. These factors act as trans-activators of the constitutive transcription of the genes for ribosomal proteins S33 and L3 respectively. We now present evidence that GFI, TAF and SUF are probably the same protein. We speculate that one of the functions of GFI is the adjustment of the expression of a number of gene families to cell growth rate.
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
K. Miyoshi, T. Miyakawa, and K. Mizuta Repression of rRNA synthesis due to a secretory defect requires the C-terminal silencing domain of Rap1p in Saccharomyces cerevisiae Nucleic Acids Res., August 15, 2001; 29(16): 3297 - 3303. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Tsuno, K. Miyoshi, R. Tsujii, T. Miyakawa, and K. Mizuta RRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis in Saccharomyces cerevisiae Mol. Cell. Biol., March 15, 2000; 20(6): 2066 - 2074. [Abstract] [Full Text] |
||||
![]() |
B. Li, C. R. Nierras, and J. R. Warner Transcriptional Elements Involved in the Repression of Ribosomal Protein Synthesis Mol. Cell. Biol., August 1, 1999; 19(8): 5393 - 5404. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Pierce, M. Wagner, J. Xie, V. Gailus-Durner, J. Six, A. K. Vershon, and E. Winter Transcriptional Regulation of the SMK1 Mitogen-Activated Protein Kinase Gene during Meiotic Development in Saccharomyces cerevisiae Mol. Cell. Biol., October 1, 1998; 18(10): 5970 - 5980. [Abstract] [Full Text] |
||||
![]() |
Y Marahrens and B Stillman A yeast chromosomal origin of DNA replication defined by multiple functional elements Science, February 14, 1992; 255(5046): 817 - 823. [Abstract] [PDF] |
||||
![]() |
P R Rhode, K S Sweder, K F Oegema, and J L Campbell The gene encoding ARS-binding factor I is essential for the viability of yeast. Genes & Dev., December 1, 1989; 3(12a): 1926 - 1939. [Abstract] [PDF] |
||||
![]() |
J. Diffley and B Stillman Similarity between the transcriptional silencer binding proteins ABF1 and RAP1 Science, November 24, 1989; 246(4933): 1034 - 1038. [Abstract] [PDF] |
||||



