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Nucleic Acids Research, 1989, Vol. 17, No. 23 9527-9530
© 1989


MOLECULAR BIOLOGY

The Caenorhabditis eleguns genome contains monomorphic minisatellites and simple sequences

André G. Uitterlinden, P. Eline Slagboom, Thomas E. Johnson1 and Jan Vijg

Department of Molecular Biology, TNO Institute for Experimental Gerontology PO Box 5815, 2280 HV Rijswijk, The Netherlands 1Institute for Behavioral Genetics, University of Colorado Boulder, CO 80309, USA

Received October 27, 1989. Accepted November 3, 1989.

Many species have been shown to contain tandemly repeated short sequence DNA kinown as minisatellites and simple sequence motifs. Due to allelic variation in the copy number of the repeat unit these loci are usually highly polymorphic. Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA. However, when two independent strains were compared no polymorphism for these sequences could be detected.


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