Skip Navigation

This Article
Right arrow Print PDF (4114K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (27)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Parro, V.
Right arrow Articles by Mellado, R. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Parro, V.
Right arrow Articles by Mellado, R. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1991, Vol. 19, No. 10 2623-2627
© 1991

MOLECULAR BIOLOGY

Transcription of genes involved in the earliest steps of actinorhodin biosynthesis in Streptomyces coelicolor

Victor Parro, David A. Hopwood1, F. Malpartida and Rafael P. Mellado*

Centro Nacional de Biotecnologia Serrano 115 bis, 28006 Madrid, Spain 1John Innes Institute Colney Lane, Norwich NR4 7UH, UK

* To whom correspondence should be addressed

Received February 28, 1991. Revised April 23, 1991. Accepted April 23, 1991.

A 170bp long BamHI-Sau3A DNA fragment from the actIII-actI intergenic region of the actinorhodin (Act) biosynthetlc gene cluster of Streptomyces coelicolor A3(2) contains two promoters directing transcription In a divergent manner. One of them, the acflll promoter, is responsable for the transcription of the acflll gene and the other controls transcription of the adjacent actIII region in the opposite direction. Weak activity of the actIII promoter can be detected in Streptomyces lividans and Bacilius subtilis in the absence but not in the presence of glucose. Neither promoter seems to function in Escherichia coli.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Appl. Environ. Microbiol.Home page
R. Fong, Z. Hu, C. R. Hutchinson, J. Huang, S. Cohen, and C. Kao
Characterization of a Large, Stable, High-Copy-Number Streptomyces Plasmid That Requires Stability and Transfer Functions for Heterologous Polyketide Overproduction
Appl. Envir. Microbiol., February 15, 2007; 73(4): 1296 - 1307.
[Abstract] [Full Text] [PDF]

Home page
 MicrobiologyHome page
A. Palacin, R. de la Fuente, I. Valle, L. A. Rivas, and R. P. Mellado
Streptomyces lividans contains a minimal functional signal recognition particle that is involved in protein secretion
Microbiology, September 1, 2003; 149(9): 2435 - 2442.
[Abstract] [Full Text] [PDF]

Home page
 J. Bacteriol.Home page
N. Geukens, E. Lammertyn, L. Van Mellaert, S. Schacht, K. Schaerlaekens, V. Parro, S. Bron, Y. Engelborghs, R. P. Mellado, and J. Anne
Membrane Topology of the Streptomyces lividans Type I Signal Peptidases
J. Bacteriol., August 15, 2001; 183(16): 4752 - 4760.
[Abstract] [Full Text] [PDF]

Home page
 MicrobiologyHome page
V. Parro, S. Schacht, J. Anne, and R. P. Mellado
Four genes encoding different type I signal peptidases are organized in a cluster in Streptomyces lividans TK21
Microbiology, September 1, 1999; 145(9): 2255 - 2263.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.