Skip Navigation

This Article
Right arrow Print PDF (429K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (34)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Chakraburtty, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chakraburtty, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1975, Vol. 2, No. 10 1793-1804
© 1975

Articles

Effect of sodium bisulfite modification on the arginine acceptance of E.coli tRNAArg

Kalpana Chakraburtty

Department of Biochemistry, Medical College of Wisconsin Milwaukee, WI 53233, USA

Received August 6, 1975. Escherichia coli tRNAArg was treated with sodium bisulfite to convert exposed cytosine residues to uracil. This treatment resulted in the loss of amino acid acceptance of the tRNAArg with pseudo first-order reaction kinetics. The active and inactive molecules were separated after about 60 percent inactivation and analyzed for U in various positions by fingerprinting of the oligonucleotides produced by nucleases. The results show that C to U base transitions in the dihydrouridine loop and in the CCA terminus have no effect on the aminoacylation of this tRNA. Deamination of a cytosine residue at the second position of the anticodon resulted in the loss of amino acid acceptor activity of arginine transfer RNA.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 ScienceHome page
L. Schulman and H Pelka
The anticodon contains a major element of the identity of arginine transfer RNAs
Science, December 22, 1989; 246(4937): 1595 - 1597.
[Abstract] [PDF]

Home page
 ScienceHome page
L. Schulman and H Pelka
Anticodon switching changes the identity of methionine and valine transfer RNAs
Science, November 4, 1988; 242(4879): 765 - 768.
[Abstract] [PDF]

Home page
 ScienceHome page
W. McClain and K Foss
Changing the acceptor identity of a transfer RNA by altering nucleotides in a "variable pocket"
Science, September 30, 1988; 241(4874): 1804 - 1807.
[Abstract] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. Tomita, T. Ogawa, T. Uozumi, K. Watanabe, and H. Masaki
A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops
PNAS, July 18, 2000; 97(15): 8278 - 8283.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.