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Nucleic Acids Research, 1975, Vol. 2, No. 12 2223-2236
© 1975

Articles

Peptidyl transferase centre of bacterial ribosomes: substrate specificity and binding sites

A.A. Krayevsky, M.K. Kukhanova and B.P. Gottikh

Institute of Molecular Biology, Academy of Sciences of the USSR Vavilov str., 117312 Moscow, USSR

Received October 1, 1975. A detailed scheme of the Peptidyl Transferase Centre of bacterial ribosomes is proposed by summarizing the literature data on the substrate specificity of the acceptor and donor sites. According to the proposed scheme only the elements of the donor and acceptor having a stable structure bind with the ribosome. The present paper proposes such main elements for the donor and acceptor.


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