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Nucleic Acids Research, 1975, Vol. 2, No. 4 595-601
© 1975

Articles

Poly(U, s4U) as a synthetic messenger RNA for polyphenylalanine synthesis in a cell-free system derived from rat liver

M. Keren-Zur, A.A. Hochberg, N. de Groot and Y. Lapidot

Department of Biological Chemistry, The Hebrew University Jerusalem, Israel

Received March 5, 1975. Two different U and s4U containing polymers with U:s4U ratio of 3:1 and 5:1 were synthesized. Their activity as messenger RNA was studied in an amino acid incorporation cell-free system from rat liver. It was shown that both copolymers can stimulate the incorporation of phenylalanine into oligophenylalanyl-tRNA.


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