Skip Navigation

This Article
Right arrow Print PDF (3181K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (171)
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Zimmern, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zimmern, D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1975, Vol. 2, No. 7 1189-1202
© 1975

Articles

The 5' end group of tobacco mosaic virus RNA is m7G5'ppp5'Gp

David Zimmern

Medical Research Council Laboratory of Molecular Biology Hills Road, Cambridge CB2 2QH, UK

Received May 28, 1975. RNA extracted from CsCl.purified virions of tobacco mosaic virus is shown to give rise to an unusual nucleotide on digestion with RNAase T2, in addition to the four major nucleotides. This minor component has the electrophoretic characteristics of a phosphorylated end group, but is partially resistant to bacterial alkaline phosphatase. It is, however, a substrate for venom phos-phodiesterase or nucleotide pyrophosphatase, yielding products which imply the structure m7G5'ppp5'Gp. TMV RNA, like many animal cellular and viral mRNAs recently examined, therefore has a 5' terminus blocked by a methylated nucleotide inverted with respect to the rest of the chain.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
V. A. Efimov, O. G. Chakhmakhcheva, J. Archdeacon, J. M. Fernandez, O. N. Fedorkin, Yu. L. Dorokhov, and J. G. Atabekov
Detection of the 5'-cap structure of messenger RNAs with the use of the cap-jumping approach
Nucleic Acids Res., November 15, 2001; 29(22): 4751 - 4759.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
T. Lin, A. J. Clark, Z. Chen, M. Shanks, J.-B. Dai, Y. Li, T. Schmidt, P. Oxelfelt, G. P. Lomonossoff, and J. E. Johnson
Structural Fingerprinting: Subgrouping of Comoviruses by Structural Studies of Red Clover Mottle Virus to 2.4-A Resolution and Comparisons with Other Comoviruses
J. Virol., January 1, 2000; 74(1): 493 - 504.
[Abstract] [Full Text]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.