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Nucleic Acids Research, 1992, Vol. 20, No. 5 1011-1016
© 1992


MOLECULAR BIOLOGY

Yeast ribosomal proteins: XIII. Saccharomyces cerevisiae YL8A gene, interrupted with two introns, encodes a homolog of mammalian L7

Keiko Mizuta, Tetsuo Hashimoto* and Eiko Otaka

Department of Biochemistry and Biophysics, Research Institute for Nuclear Medicine and Biology, Hiroshima University 2-3, Kasumi 1-chome, Minami-ku, Hiroshima 734, Japan

Received December 31, 1991. Revised February 3, 1992. Accepted February 3, 1992.

We isolated and sequenced a gene, YL8A, encoding ribosomal protein YL8 of Saccharomyces cerevisiae. It is one of the two duplicated genes encoding YL8 and is located on chromosome VII while the other is on chromosome XVI. The haploid strains carrying disrupted YL8A grew more slowly than the parent strain. The open reading frame is interrupted with two introns. The predicted amino acid sequence reveals that yeast YL8 is a homolog of mammalian ribosomal protein L7, E.coli L30 and others.


*Present address: The Institute of Statistical Mathematics, 4-6-7 Minami-Azabu, Minato-ku, Tokyo 106, Japan


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