Nucleic Acids Research, 1994, Vol. 22, No. 2 174-179
© 1994
MOLECULAR BIOLOGY |
Phylogenetic analysis of the core histones H2A, H2B, H3, and H4
Department of Biology, University of Rochester Rochester, NY 14627, USA
*To whom correspondence should be addressed
Received October 26, 1993. Accepted December 7, 1993.
Despite the ubiquity of histones In eukaryotes and their Important role in determining the structure and function of chromatln, no detailed studies of the evolution of the histories have been reported. We have constructed phylogenetic trees for the core histones H2A, H2B, H3, and H4. Histones which form dimers (H2A/H2B and H3/H4) have very similar trees and appear to have co-evolved, with the exception of the divergent sea urchin testis H2B8, for which no corresponding divergent H2As have been identified. The trees for H2A and H2B also support the theory that animals and fungi have a common ancestor. H3 and H4 are 10-fold less divergent than H2A and H2B. Three evolutionary histories are observed for hlstone variants. H2A.F/Z-type variants arose once early in evolution, while H2A.X variants arose separately, during the evolution of multicellular animals. H3.3-type variants have arisen in multiple Independent events.
+Present address: University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, PO Box 363, Rochester, NY 14642, USA.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  W. Gad and Y. Kim A viral histone H4 encoded by Cotesia plutellae bracovirus inhibits haemocyte-spreading behaviour of the diamondback moth, Plutella xylostella J. Gen. Virol., April 1, 2008; 89(4): 931 - 938. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. E. Lowell, F. Kaiser, C. J. Janzen, and G. A. M. Cross Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei J. Cell Sci., December 15, 2005; 118(24): 5721 - 5730. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Good and M. W. Nachman Rates of Protein Evolution Are Positively Correlated with Developmental Timing of Expression During Mouse Spermatogenesis Mol. Biol. Evol., April 1, 2005; 22(4): 1044 - 1052. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Pineau, M. Henry, R. Suspene, A. Marchio, A. Dettai, R. Debruyne, T. Petit, A. Lecu, P. Moisson, A. Dejean, et al. A Universal Primer Set for PCR Amplification of Nuclear Histone H4 Genes from All Animal Species Mol. Biol. Evol., March 1, 2005; 22(3): 582 - 588. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Ha, S. Ceryak, and S. R. Patierno Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of {gamma}-H2AX Carcinogenesis, November 1, 2004; 25(11): 2265 - 2274. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Cobbe and M. M. S. Heck The Evolution of SMC Proteins: Phylogenetic Analysis and Structural Implications Mol. Biol. Evol., February 1, 2004; 21(2): 332 - 347. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Furuta, H. Takemura, Z.-Y. Liao, G. J. Aune, C. Redon, O. A. Sedelnikova, D. R. Pilch, E. P. Rogakou, A. Celeste, H. T. Chen, et al. Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Cleavage Complexes J. Biol. Chem., May 23, 2003; 278(22): 20303 - 20312. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Q. Ren and M. A. Gorovsky The Nonessential H2A N-Terminal Tail Can Function as an Essential Charge Patch on the H2A.Z Variant N-Terminal Tail Mol. Cell. Biol., April 15, 2003; 23(8): 2778 - 2789. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Hays, J. Swanson, and E. U. Selker Identification and Characterization of the Genes Encoding the Core Histones and Histone Variants of Neurospora crassa Genetics, March 1, 2002; 160(3): 961 - 973. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Sullivan, D. W. Sink, K. L. Trout, I. Makalowska, P. M. Taylor, A. D. Baxevanis, and D. Landsman The Histone Database Nucleic Acids Res., January 1, 2002; 30(1): 341 - 342. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. P. Rooney, H. Piontkivska, and M. Nei Molecular Evolution of the Nontandemly Repeated Genes of the Histone 3 Multigene Family Mol. Biol. Evol., January 1, 2002; 19(1): 68 - 75. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Jackson and M. A. Gorovsky Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants Nucleic Acids Res., October 1, 2000; 28(19): 3811 - 3816. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Wu, A. G. McArthur, A. Fiser, M. L. Sogin, and M. M Core Histones of the Amitochondriate Protist, Giardia lamblia Mol. Biol. Evol., August 1, 2000; 17(8): 1156 - 1163. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. P. Rogakou, D. R. Pilch, A. H. Orr, V. S. Ivanova, and W. M. Bonner DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139 J. Biol. Chem., March 6, 1998; 273(10): 5858 - 5868. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A High-Density Rice Genetic Linkage Map with 2275 Markers Using a Single F2 Population Genetics, January 1, 1998; 148(1): 479 - 494.
|
|