Nucleic Acids Research, 1995, Vol. 23, No. 18 3696-3703
© 1995
COMPUTATIONAL BIOLOGY |
Computer assisted identification and classification of streptomycete promoters
Departments of Microbiology, University of Cape Town Rondebosch 7700, Cape Town, South Africa 1Medical Microbiology, University of Cape Town Rondebosch 7700, Cape Town, South Africa
*To whom correspondence should be addressed
Received June 2, 1995. Revised August 17, 1995. Accepted August 17, 1995.
Short sequences that were over represented in a database of Streptomyces promoter region sequences were identified. These sequences and others that were selected on the basis of the characteristics of known promoters, were tested to determine if they were found predominantly at particular distances from the transcription start site. In several cases obvious clusters were recorded. This has allowed the objective identification of potential promoter core sequences. In some cases these may define novel promoter classes. 150 Streptomyces promoters have been listed and grouped on this basis. A new and extended consensus sequence for the Streptomyces E.coli 
70-like promoters was determined. It showed differences from that of E.coli, both in sequence and in the spacing between the –35 and –10 regions.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. K. Apel, A. Sola-Landa, A. Rodriguez-Garcia, and J. F. Martin Phosphate control of phoA, phoC and phoD gene expression in Streptomyces coelicolor reveals significant differences in binding of PhoP to their promoter regions Microbiology, October 1, 2007; 153(10): 3527 - 3537. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Schwartz, N. Grammel, E. Heinzelmann, U. Keller, and W. Wohlleben Phosphinothricin Tripeptide Synthetases in Streptomyces viridochromogenes Tu494 Antimicrob. Agents Chemother., November 1, 2005; 49(11): 4598 - 4607. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Yu. Rebets, B. Ostash, A. Luzhetskyy, S. Kushnir, M. Fukuhara, A. Bechthold, M. Nashimoto, T. Nakamura, and V. Fedorenko DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912 Microbiology, January 1, 2005; 151(1): 281 - 290. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Schwartz, S. Berger, E. Heinzelmann, K. Muschko, K. Welzel, and W. Wohlleben Biosynthetic Gene Cluster of the Herbicide Phosphinothricin Tripeptide from Streptomyces viridochromogenes Tu494 Appl. Envir. Microbiol., December 1, 2004; 70(12): 7093 - 7102. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Zhou, X. He, A. Li, F. Lei, T. Kieser, and Z. Deng Streptomyces coelicolor A3(2) Lacks a Genomic Island Present in the Chromosome of Streptomyces lividans 66 Appl. Envir. Microbiol., December 1, 2004; 70(12): 7110 - 7118. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. L. DeSanti and W. R. Strohl Characterization of the Streptomyces sp. Strain C5 snp Locus and Development of snp-Derived Expression Vectors Appl. Envir. Microbiol., March 1, 2003; 69(3): 1647 - 1654. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Heinzelmann, G. Kienzlen, S. Kaspar, J. Recktenwald, W. Wohlleben, and D. Schwartz The Phosphinomethylmalate Isomerase Gene pmi, Encoding an Aconitase-Like Enzyme, Is Involved in the Synthesis of Phosphinothricin Tripeptide in Streptomyces viridochromogenes Appl. Envir. Microbiol., August 1, 2001; 67(8): 3603 - 3609. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Namwat, C.-K. Lee, H. Kinoshita, Y. Yamada, and T. Nihira Identification of the varR Gene as a Transcriptional Regulator of Virginiamycin S Resistance in Streptomyces virginiae J. Bacteriol., March 15, 2001; 183(6): 2025 - 2031. [Abstract] [Full Text]
|
|
|
|
|
|
J. A. Aínsa, N. J. Ryding, N. Hartley, K. C. Findlay, C. J. Bruton, and K. F. Chater WhiA, a Protein of Unknown Function Conserved among Gram-Positive Bacteria, Is Essential for Sporulation in Streptomyces coelicolor A3(2) J. Bacteriol., October 1, 2000; 182(19): 5470 - 5478. [Abstract] [Full Text]
|
|
|
|
|
|
J. Ishikawa, A. Sunada, R. Oyama, and K. Hotta Identification and Characterization of the Point Mutation Which Affects the Transcription Level of the Chromosomal 3-N-Acetyltransferase Gene of Streptomyces griseus SS-1198 Antimicrob. Agents Chemother., February 1, 2000; 44(2): 437 - 440. [Abstract] [Full Text]
|
|
|
|
|
|
S. Kitani, H. Kinoshita, T. Nihira, and Y. Yamada In Vitro Analysis of the Butyrolactone Autoregulator Receptor Protein (FarA) of Streptomyces lavendulae FRI-5 Reveals that FarA Acts as a DNA-Binding Transcriptional Regulator That Controls Its Own Synthesis J. Bacteriol., August 15, 1999; 181(16): 5081 - 5084. [Abstract] [Full Text]
|
|
|
|
|
|
A. Schlösser, J. Jantos, K. Hackmann, and H. Schrempf Characterization of the Binding Protein-Dependent Cellobiose and Cellotriose Transport System of the Cellulose Degrader Streptomyces reticuli Appl. Envir. Microbiol., June 1, 1999; 65(6): 2636 - 2643. [Abstract] [Full Text]
|
|
|
|
|
|
C.-K. Lee, Y. Kamitani, T. Nihira, and Y. Yamada Identification and In Vivo Functional Analysis of a Virginiamycin S Resistance Gene (varS) from Streptomyces virginiae J. Bacteriol., May 15, 1999; 181(10): 3293 - 3297. [Abstract] [Full Text]
|
|
|
|
|
|
M. S. B. Paget, L. Chamberlin, A. Atrih, S. J. Foster, and M. J. Buttner Evidence that the Extracytoplasmic Function Sigma Factor sigma E Is Required for Normal Cell Wall Structure in Streptomyces coelicolor A3(2) J. Bacteriol., January 1, 1999; 181(1): 204 - 211. [Abstract] [Full Text]
|
|