Nucleic Acids Research, Vol 25, Issue 1 104-106, Copyright © 1997 by Oxford University Press
AE Souza, T Hermann and HU Goringer
The RNA editing process in protozoan parasites is controlled by small RNA
molecules known as guide RNAs (gRNAs). The gRNA database is a comprehensive
compilation of published guide RNA sequences from eight different
kinetoplastid organisms. In addition to the RNA primary sequences,
information on the gene localization, the experimental verification of the
transcripts, and literature citations are provided. Accessory information
includes the secondary structures of fourTrypanosoma bruceigRNAs as well as
a computer modelled three dimensional gRNA structure. The database is made
available as a hypertext document accessible via the World Wide Web (WWW)
or from the authors in a printed form.
ARTICLES
The guide RNA database
Laboratorium fur Molekulare Biologie, Genzentrum der LMU Munchen am MPI fur Biochemie, Am Klopferspitz 18, 82152 Martinsried, Germany.
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