Nucleic Acids Research, Vol 25, Issue 13 2595-2597, Copyright © 1997 by Oxford University Press
NW Kim and F Wu
The telomeric repeat amplification protocol (TRAP) assay has been used to
test telomerase activity in numerous cancer specimens. We describe primers,
controls and quantification methods for the TRAP assay to accurately
measure the level of telomerase activity in clinical samples. The assay is
reliable and reproducible in routine analyses and can be used to estimate
the processivity of telomerase activity.
ARTICLES
Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
Geron Corporation, Menlo Park, CA 94025, USA. nkim@geron.com
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