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Nucleic Acids Research, Vol 25, Issue 18 3672-3680, Copyright © 1997 by Oxford University Press

ARTICLES

A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing

WT Markiewicz, G Groger, R Rosch, A Zebrowska, M Markiewicz, M Klotz, M Hinz, P Godzina and H Seliger
Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12, PL-61704 Poznan, Poland. markw@ibch.posnon.pl

A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported. Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown.
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P. J. O'Sullivan, M. Burke, A. E. Soini, and D. B. Papkovsky
Synthesis and evaluation of phosphorescent oligonucleotide probes for hybridisation assays
Nucleic Acids Res., November 1, 2002; 30(21): e114 - e114.
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