Nucleic Acids Research, Vol 25, Issue 21 4173-4180, Copyright © 1997 by Oxford University Press
TR Burglin
A new Caenorhabditis elegans homeobox gene, ceh-25, is described that
belongs to the TALE superclass of atypical homeodomains, which are
characterized by three extra residues between helix 1 and helix 2. ORF and
PCR analysis revealed a novel type of alternative splicing within the
homeobox. The alternative splicing occurs such that two different
homeodomains can be generated, which differ in their first 25 amino acids.
ceh-25 is an orthologue of the vertebrate Meis genes and it shares a new
conserved domain of 130 amino acids with them. A thorough analysis of all
TALE homeobox genes was performed and a new classification is presented.
Four TALE classes are identified in animals: PBC, MEIS, TGIF and IRO
(Iroquois); two types in fungi: the mating type genes (M-ATYP) and the CUP
genes; and two types in plants: KNOX and BEL. The IRO class has a new
conserved motif downstream of the homeodomain. For the KNOX class, a
conserved domain, the KNOX domain, was defined upstream of the homeodomain.
Comparison of the KNOX domain and the MEIS domain shows significant
sequence similarity revealing the existence of an archetypal group of
homeobox genes that encode two associated conserved domains. Thus TALE
homeobox genes were already present in the common ancestor of plants, fungi
and animals and represent a branch distinct from the typical homeobox
genes.
ARTICLES
Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals
Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  K. Mukherjee, L. Brocchieri, and T. R. Burglin A Comprehensive Classification and Evolutionary Analysis of Plant Homeobox Genes Mol. Biol. Evol., December 1, 2009; 26(12): 2775 - 2794. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. J. Hatcher and C. T. Basson Specification of the Cardiac Conduction System by Transcription Factors Circ. Res., September 25, 2009; 105(7): 620 - 630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Stankunas, C. Shang, K. Y. Twu, S.-C. Kao, N. A. Jenkins, N. G. Copeland, M. Sanyal, L. Selleri, M. L. Cleary, and C.-P. Chang Pbx/Meis Deficiencies Demonstrate Multigenetic Origins of Congenital Heart Disease Circ. Res., September 26, 2008; 103(7): 702 - 709. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Xu, D. Geerts, K. Qian, H. Zhang, and G. Zhu Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation Hum. Reprod., June 1, 2008; 23(6): 1394 - 1406. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Magnani and S. Hake KNOX Lost the OX: The Arabidopsis KNATM Gene Defines a Novel Class of KNOX Transcriptional Regulators Missing the Homeodomain PLANT CELL, April 1, 2008; 20(4): 875 - 887. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Bessa, M. J. Tavares, J. Santos, H. Kikuta, M. Laplante, T. S. Becker, J. L. Gomez-Skarmeta, and F. Casares meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye Development, March 1, 2008; 135(5): 799 - 803. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Heine, E. Dohle, K. Bumsted-O'Brien, D. Engelkamp, and D. Schulte Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development Development, March 1, 2008; 135(5): 805 - 811. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Chatterjee, A. K. Banerjee, and D. J. Hannapel A BELL1-Like Gene of Potato Is Light Activated and Wound Inducible Plant Physiology, December 1, 2007; 145(4): 1435 - 1443. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. B. Deramaudt, M. M. Sachdeva, M. P. Wescott, Y. Chen, D. A. Stoffers, and A. K. Rustgi The PDX1 Homeodomain Transcription Factor Negatively Regulates the Pancreatic Ductal Cell-specific Keratin 19 Promoter J. Biol. Chem., December 15, 2006; 281(50): 38385 - 38395. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.M. Ordway, J.A. Bedell, R.W. Citek, A. Nunberg, A. Garrido, R. Kendall, J.R. Stevens, D. Cao, R.W. Doerge, Y. Korshunova, et al. Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets Carcinogenesis, December 1, 2006; 27(12): 2409 - 2423. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Banerjee, M. Chatterjee, Y. Yu, S.-G. Suh, W. A. Miller, and D. J. Hannapel Dynamics of a Mobile RNA of Potato Involved in a Long-Distance Signaling Pathway PLANT CELL, December 1, 2006; 18(12): 3443 - 3457. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Krystofova and K. A. Borkovich The Predicted G-Protein-Coupled Receptor GPR-1 Is Required for Female Sexual Development in the Multicellular Fungus Neurospora crassa. Eukaryot. Cell, September 1, 2006; 5(9): 1503 - 1516. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Noro, J. Culi, D. J. McKay, W. Zhang, and R. S. Mann Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax. Genes & Dev., June 15, 2006; 20(12): 1636 - 1650. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Zubair, S. Ishihara, S. Oka, K. Okumura, and K.-i. Morohashi Two-Step Regulation of Ad4BP/SF-1 Gene Transcription during Fetal Adrenal Development: Initiation by a Hox-Pbx1-Prep1 Complex and Maintenance via Autoregulation by Ad4BP/SF-1. Mol. Cell. Biol., June 1, 2006; 26(11): 4111 - 4121. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. D. Capellini, G. Di Giacomo, V. Salsi, A. Brendolan, E. Ferretti, D. Srivastava, V. Zappavigna, and L. Selleri Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression Development, June 1, 2006; 133(11): 2263 - 2273. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Cole, C. Nolte, and W. Werr Nuclear import of the transcription factor SHOOT MERISTEMLESS depends on heterodimerization with BLH proteins expressed in discrete sub-domains of the shoot apical meristem of Arabidopsis thaliana Nucleic Acids Res., March 2, 2006; 34(4): 1281 - 1292. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q. K.-G. Tan and V. F. Irish The Arabidopsis Zinc Finger-Homeodomain Genes Encode Proteins with Unique Biochemical Properties That Are Coordinately Expressed during Floral Development Plant Physiology, March 1, 2006; 140(3): 1095 - 1108. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Liu, T. J. Strauss, M. B. Potts, and S. Cameron Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1 Development, February 15, 2006; 133(4): 641 - 650. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Bartholin, S. E. Powers, T. A. Melhuish, S. Lasse, M. Weinstein, and D. Wotton TGIF Inhibits Retinoid Signaling Mol. Cell. Biol., February 1, 2006; 26(3): 990 - 1001. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Penkov, P. Di Rosa, L. Fernandez Diaz, V. Basso, E. Ferretti, F. Grassi, A. Mondino, and F. Blasi Involvement of Prep1 in the {alpha}{beta} T-Cell Receptor T-Lymphocytic Potential of Hematopoietic Precursors Mol. Cell. Biol., December 15, 2005; 25(24): 10768 - 10781. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Nam and M. Nei Evolutionary Change of the Numbers of Homeobox Genes in Bilateral Animals Mol. Biol. Evol., December 1, 2005; 22(12): 2386 - 2394. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Nei Selectionism and Neutralism in Molecular Evolution Mol. Biol. Evol., December 1, 2005; 22(12): 2318 - 2342. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Bilioni, G. Craig, C. Hill, and H. McNeill Iroquois transcription factors recognize a unique motif to mediate transcriptional repression in vivo PNAS, October 11, 2005; 102(41): 14671 - 14676. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Ferretti, F. Cambronero, S. Tumpel, E. Longobardi, L. M. Wiedemann, F. Blasi, and R. Krumlauf Hoxb1 Enhancer and Control of Rhombomere 4 Expression: Complex Interplay between PREP1-PBX1-HOXB1 Binding Sites Mol. Cell. Biol., October 1, 2005; 25(19): 8541 - 8552. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Mercader, E. M. Tanaka, and M. Torres Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins Development, September 15, 2005; 132(18): 4131 - 4142. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Brendolan, E. Ferretti, V. Salsi, K. Moses, S. Quaggin, F. Blasi, M. L. Cleary, and L. Selleri A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny Development, July 1, 2005; 132(13): 3113 - 3126. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Huang, M. Rastegar, C. Bodner, S.-L. Goh, I. Rambaldi, and M. Featherstone MEIS C Termini Harbor Transcriptional Activation Domains That Respond to Cell Signaling J. Biol. Chem., March 18, 2005; 280(11): 10119 - 10127. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Hull, M.-J. Boily, and J. Heitman Sex-Specific Homeodomain Proteins Sxi1{alpha} and Sxi2a Coordinately Regulate Sexual Development in Cryptococcus neoformans Eukaryot. Cell, March 1, 2005; 4(3): 526 - 535. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Harrison, M. Moller, J. Langdale, Q. Cronk, and A. Hudson The Role of KNOX Genes in the Evolution of Morphological Novelty in Streptocarpus PLANT CELL, February 1, 2005; 17(2): 430 - 443. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. A. Samad, M. J. Geisen, G. Caronia, I. Varlet, V. Zappavigna, J. Ericson, C. Goridis, and F. M. Rijli Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins Development, August 15, 2004; 131(16): 4071 - 4083. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Lecaudey, I. Anselme, F. Rosa, and S. Schneider-Maunoury The zebrafish Iroquois gene iro7 positions the r4/r5 boundary and controls neurogenesis in the rostral hindbrain Development, July 1, 2004; 131(13): 3121 - 3131. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 X. Wang and J. Zhang Rapid Evolution of Mammalian X-Linked Testis-Expressed Homeobox Genes Genetics, June 1, 2004; 167(2): 879 - 888. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Qin, J. M. Haberbusch, Z. Zhang, K. J. Soprano, and D. R. Soprano Pre-B Cell Leukemia Transcription Factor (PBX) Proteins Are Important Mediators for Retinoic Acid-dependent Endodermal and Neuronal Differentiation of Mouse Embryonal Carcinoma P19 Cells J. Biol. Chem., April 16, 2004; 279(16): 16263 - 16271. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Deflorian, N. Tiso, E. Ferretti, D. Meyer, F. Blasi, M. Bortolussi, and F. Argenton Prep1.1 has essential genetic functions in hindbrain development and cranial neural crest cell differentiation Development, February 1, 2004; 131(3): 613 - 627. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Glavic, F. Silva, M. J. Aybar, F. Bastidas, and R. Mayor Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos Development, January 15, 2004; 131(2): 347 - 359. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Hyman, L. Bartholin, S. J. Newfeld, and D. Wotton Drosophila TGIF Proteins Are Transcriptional Activators Mol. Cell. Biol., December 15, 2003; 23(24): 9262 - 9274. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Longobardi and F. Blasi Overexpression of PREP-1 in F9 Teratocarcinoma Cells Leads to a Functionally Relevant Increase of PBX-2 by Preventing Its Degradation J. Biol. Chem., October 3, 2003; 278(40): 39235 - 39241. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Byrne, A. T. Groover, J. R. Fontana, and R. A. Martienssen Phyllotactic pattern and stem cell fate are determined by the Arabidopsis homeobox gene BELLRINGER Development, September 1, 2003; 130(17): 3941 - 3950. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. A. Wray, M. W. Hahn, E. Abouheif, J. P. Balhoff, M. Pizer, M. V. Rockman, and L. A. Romano The Evolution of Transcriptional Regulation in Eukaryotes Mol. Biol. Evol., September 1, 2003; 20(9): 1377 - 1419. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Nam, C. W. dePamphilis, H. Ma, and M. Nei Antiquity and Evolution of the MADS-Box Gene Family Controlling Flower Development in Plants Mol. Biol. Evol., September 1, 2003; 20(9): 1435 - 1447. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. A. LaRonde-LeBlanc and C. Wolberger Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior Genes & Dev., August 15, 2003; 17(16): 2060 - 2072. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Aspock, G. Ruvkun, and T. R. Burglin The Caenorhabditis elegans ems class homeobox gene ceh-2 is required for M3 pharynx motoneuron function Development, August 1, 2003; 130(15): 3369 - 3378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ayyar, J. Jiang, A. Collu, H. White-Cooper, and R. A. H. White Drosophila TGIF is essential for developmentally regulated transcription in spermatogenesis Development, July 1, 2003; 130(13): 2841 - 2852. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Wang and R. S. Mann Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis Development, July 1, 2003; 130(13): 2853 - 2865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Chen, F. M. Rosin, S. Prat, and D. J. Hannapel Interacting Transcription Factors from the Three-Amino Acid Loop Extension Superclass Regulate Tuber Formation Plant Physiology, July 1, 2003; 132(3): 1391 - 1404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Huang, M. Paliouras, I. Rambaldi, P. Lasko, and M. Featherstone Nonmuscle Myosin Promotes Cytoplasmic Localization of PBX Mol. Cell. Biol., May 15, 2003; 23(10): 3636 - 3645. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. M. Rosin, J. K. Hart, H. T. Horner, P. J. Davies, and D. J. Hannapel Overexpression of a Knotted-Like Homeobox Gene of Potato Alters Vegetative Development by Decreasing Gibberellin Accumulation Plant Physiology, May 1, 2003; 132(1): 106 - 117. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Van Auken, D. Weaver, B. Robertson, M. Sundaram, T. Saldi, L. Edgar, U. Elling, M. Lee, Q. Boese, and W. B. Wood Roles of the Homothorax/Meis/Prep homolog UNC-62 and the Exd/Pbx homologs CEH-20 and CEH-40 in C. elegans embryogenesis Development, March 13, 2003; 129(22): 5255 - 5268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Itoh, T. Kudoh, M. Dedekian, C.-H. Kim, and A. B. Chitnis A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary Development, March 7, 2003; 129(10): 2317 - 2327. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. F. Tioni, D. H. Gonzalez, and R. L. Chan Knotted1-like genes are strongly expressed in differentiated cell types in sunflower J. Exp. Bot., February 1, 2003; 54(383): 681 - 690. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Salesse and C. M. Verfaillie BCR/ABL-mediated Increased Expression of Multiple Known and Novel Genes That May Contribute to the Pathogenesis of Chronic Myelogenous Leukemia Mol. Cancer Ther., February 1, 2003; 2(2): 173 - 182. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Sprules, N. Green, M. Featherstone, and K. Gehring Lock and Key Binding of the HOX YPWM Peptide to the PBX Homeodomain J. Biol. Chem., January 3, 2003; 278(2): 1053 - 1058. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Hull, R. C. Davidson, and J. Heitman Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha Genes & Dev., December 1, 2002; 16(23): 3046 - 3060. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P Debeer, C Bacchelli, P J Scambler, L De Smet, J-P Fryns, and F R Goodman Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD13 and a polyalanine tract expansion in HOXA13 J. Med. Genet., November 1, 2002; 39(11): 852 - 856. [Full Text] [PDF]
|
|
|
|
|
|
H. M. S. Smith, I. Boschke, and S. Hake Selective interaction of plant homeodomain proteins mediates high DNA-binding affinity PNAS, July 9, 2002; 99(14): 9579 - 9584. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Fognani, C. Kilstrup-Nielsen, J. Berthelsen, E. Ferretti, V. Zappavigna, and F. Blasi Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors Nucleic Acids Res., May 1, 2002; 30(9): 2043 - 2051. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation Development, January 4, 2002; 129(7): 1609 - 1621. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Sato, Y. Aoki, and M. Matsuoka A Loss-of-Function Mutation in the Rice KNOX Type Homeobox Gene, OSH3 Plant Cell Physiol., January 1, 2002; 43(1): 44 - 51. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. C. Mahajan and S. M. Weissman DNA-dependent adenosine triphosphatase (helicaselike transcription factor) activates beta -globin transcription in K562 cells Blood, January 1, 2002; 99(1): 348 - 356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Bharathan and N. R. Sinha The Regulation of Compound Leaf Development Plant Physiology, December 1, 2001; 127(4): 1533 - 1538. [Full Text] [PDF]
|
|
|
|
|
|
A. Inbal, N. Halachmi, C. Dibner, D. Frank, and A. Salzberg Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development Development, September 15, 2001; 128(18): 3405 - 3413. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Wotton, P. S. Knoepfler, C. D. Laherty, R. N. Eisenman, and J. Massague The Smad Transcriptional Corepressor TGIF Recruits mSin3 Cell Growth Differ., September 1, 2001; 12(9): 457 - 463. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nagasaki, T. Sakamoto, Y. Sato, and M. Matsuoka Functional Analysis of the Conserved Domains of a Rice KNOX Homeodomain Protein, OSH15 PLANT CELL, September 1, 2001; 13(9): 2085 - 2098. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Banerjee-Basu and A. D. Baxevanis Molecular evolution of the homeodomain family of transcription factors Nucleic Acids Res., August 1, 2001; 29(15): 3258 - 3269. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Cavodeassi, J. Modolell, and J. L. Gomez-Skarmeta The Iroquois family of genes: from body building to neural patterning Development, August 1, 2001; 128(15): 2847 - 2855. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Sakakibara, T. Nishiyama, M. Kato, and M. Hasebe Isolation of Homeodomain-Leucine Zipper Genes from the Moss Physcomitrella patens and the Evolution of Homeodomain-Leucine Zipper Genes in Land Plants Mol. Biol. Evol., April 1, 2001; 18(4): 491 - 502. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Kurant, D. Eytan, and A. Salzberg Mutational Analysis of the Drosophila homothorax Gene Genetics, February 1, 2001; 157(2): 689 - 698. [Abstract] [Full Text]
|
|
|
|
|
|
J Gomez-Skarmeta, E de La Calle-Mustienes, and J Modolell The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4 Development, January 2, 2001; 128(4): 551 - 560. [Abstract] [PDF]
|
|
|
|
|
|
V. C. Bromleigh and L. P. Freedman p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells Genes & Dev., October 15, 2000; 14(20): 2581 - 2586. [Abstract] [Full Text]
|
|
|
|
 |
|
 T. Peters, R. Dildrop, K. Ausmeier, and U. Rüther Organization of Mouse Iroquois Homeobox Genes in Two Clusters Suggests a Conserved Regulation and Function in Vertebrate Development Genome Res., October 1, 2000; 10(10): 1453 - 1462. [Abstract] [Full Text]
|
|
|
|
 |
|
 U. Kues Life History and Developmental Processes in the Basidiomycete Coprinus cinereus Microbiol. Mol. Biol. Rev., June 1, 2000; 64(2): 316 - 353. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J Liu and A Fire Overlapping roles of two Hox genes and the exd ortholog ceh-20 in diversification of the C. elegans postembryonic mesoderm Development, January 12, 2000; 127(23): 5179 - 5190. [Abstract] [PDF]
|
|
|
|
|
|
E Ferretti, H Marshall, H Popperl, M Maconochie, R Krumlauf, and F Blasi Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins Development, January 1, 2000; 127(1): 155 - 166. [Abstract] [PDF]
|
|
|
|
|
|
D. Wotton, R. S. Lo, L.-A. C. Swaby, and J. Massague Multiple Modes of Repression by the Smad Transcriptional Corepressor TGIF J. Biol. Chem., December 24, 1999; 274(52): 37105 - 37110. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Shanmugam, N. C. Green, I. Rambaldi, H. U. Saragovi, and M. S. Featherstone PBX and MEIS as Non-DNA-Binding Partners in Trimeric Complexes with HOX Proteins Mol. Cell. Biol., November 1, 1999; 19(11): 7577 - 7588. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Sentoku, Y. Sato, N. Kurata, Y. Ito, H. Kitano, and M. Matsuoka Regional Expression of the Rice KN1-Type Homeobox Gene Family during Embryo, Shoot, and Flower Development PLANT CELL, September 1, 1999; 11(9): 1651 - 1664. [Abstract] [Full Text]
|
|
|
|
|
|
T. Sakamoto, A. Nishimura, M. Tamaoki, M. Kuba, H. Tanaka, S. Iwahori, and M. Matsuoka The Conserved KNOX Domain Mediates Specificity of Tobacco KNOTTED1-Type Homeodomain Proteins PLANT CELL, August 1, 1999; 11(8): 1419 - 1432. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Jacobs, C. A. Schnabel, and M. L. Cleary Trimeric Association of Hox and TALE Homeodomain Proteins Mediates Hoxb2 Hindbrain Enhancer Activity Mol. Cell. Biol., July 1, 1999; 19(7): 5134 - 5142. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Ori, M. T. Juarez, D. Jackson, J. Yamaguchi, G. M. Banowetz, and S. Hake Leaf Senescence Is Delayed in Tobacco Plants Expressing the Maize Homeobox Gene knotted1 under the Control of a Senescence-Activated Promoter PLANT CELL, June 1, 1999; 11(6): 1073 - 1080. [Abstract] [Full Text]
|
|
|
|
|
|
M. Affolter, T. Marty, and M. A. Vigano Balancing import and export in development Genes & Dev., April 15, 1999; 13(8): 913 - 915. [Full Text]
|
|
|
|
|
|
J. Berthelsen, C. Kilstrup-Nielsen, F. Blasi, F. Mavilio, and V. Zappavigna The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH Genes & Dev., April 15, 1999; 13(8): 946 - 953. [Abstract] [Full Text]
|
|
|
|
|
|
G. Goudet, S. Delhalle, F. Biemar, J. A. Martial, and B. Peers Functional and Cooperative Interactions between the Homeodomain PDX1, Pbx, and Prep1 Factors on the Somatostatin Promoter J. Biol. Chem., February 12, 1999; 274(7): 4067 - 4073. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ryoo, T Marty, F Casares, M Affolter, and R. Mann Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex Development, January 11, 1999; 126(22): 5137 - 5148. [Abstract] [PDF]
|
|
|
|
 |
|
 V. Kurvari, N. V. Grishin, and W. J. Snell A Gamete-specific, Sex-limited Homeodomain Protein in Chlamydomonas J. Cell Biol., December 28, 1998; 143(7): 1971 - 1980. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Sundas-Larsson, M. Svenson, H. Liao, and P. Engstrom A homeobox gene with potential developmental control function in the meristem of the conifer Picea abies PNAS, December 8, 1998; 95(25): 15118 - 15122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nakagoshi, M. Hoshi, Y.-i. Nabeshima, and F. Matsuzaki A novel homeobox gene mediates the Dpp signal to establish functional specificity within target cells Genes & Dev., September 1, 1998; 12(17): 2724 - 2734. [Abstract] [Full Text]
|
|
|
|
|
|
L. J. Bischof, N. Kagawa, J. J. Moskow, Y. Takahashi, A. Iwamatsu, A. M. Buchberg, and M. R. Waterman Members of the Meis1 and Pbx Homeodomain Protein Families Cooperatively Bind a cAMP-responsive Sequence (CRS1) from Bovine CYP17 J. Biol. Chem., April 3, 1998; 273(14): 7941 - 7948. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Melhuish and D. Wotton The Interaction of the Carboxyl Terminus-binding Protein with the Smad Corepressor TGIF Is Disrupted by a Holoprosencephaly Mutation in TGIF J. Biol. Chem., December 8, 2000; 275(50): 39762 - 39766. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Herzig, L. Fuzesi, and W. Knepel Heterodimeric Pbx-Prep1 Homeodomain Protein Binding to the Glucagon Gene Restricting Transcription in a Cell Type-dependent Manner J. Biol. Chem., September 1, 2000; 275(36): 27989 - 27999. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Liu, R. J. MacDonald, and G. H. Swift DNA Binding and Transcriptional Activation by a PDX1{middle dot}PBX1b{middle dot}MEIS2b Trimer and Cooperation with a Pancreas-specific Basic Helix-Loop-Helix Complex J. Biol. Chem., May 18, 2001; 276(21): 17985 - 17993. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Wang, L. Yin, and F. B. Hillgartner The Homeodomain Proteins PBX and MEIS1 Are Accessory Factors That Enhance Thyroid Hormone Regulation of the Malic Enzyme Gene in Hepatocytes J. Biol. Chem., June 22, 2001; 276(26): 23838 - 23848. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Melhuish, C. M. Gallo, and D. Wotton TGIF2 Interacts with Histone Deacetylase 1 and Represses Transcription J. Biol. Chem., August 17, 2001; 276(34): 32109 - 32114. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Yang, C. K. Hwang, U. M. D'Souza, S.-H. Lee, E. Junn, and M. M. Mouradian Three-amino acid Extension Loop Homeodomain Proteins Meis2 and TGIF Differentially Regulate Transcription J. Biol. Chem., June 30, 2000; 275(27): 20734 - 20741. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Penkov, S. Tanaka, G. Di Rocco, J. Berthelsen, F. Blasi, and F. Ramirez Cooperative Interactions between PBX, PREP, and HOX Proteins Modulate the Activity of the alpha 2(V) Collagen (COL5A2) Promoter J. Biol. Chem., May 26, 2000; 275(22): 16681 - 16689. [Abstract] [Full Text] [PDF]
|
|