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Nucleic Acids Research, Vol 25, Issue 3 523-529, Copyright © 1997 by Oxford University Press

ARTICLES

DIR: a novel DNA rearrangement associated with inverted repeats

DJ Pinder, CE Blake and DRF Leach
Institute of Cell and Molecular Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JR, UK.

A novel DNA rearrangement has been characterised that is both a direct and inverted repeat.This rearrangement involves the 2-fold duplication of a plasmid sequence adjacent to the site of insertion of a long palindrome.The sequence of this rearrangement suggests that it has arisen by strand slippage from the leading to the lagging strand of the replication fork as a consequence of the presence of the long palindrome.
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This article has been cited by other articles:


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K. S. Lobachev, B. M. Shor, H. T. Tran, W. Taylor, J. D. Keen, M. A. Resnick, and D. A. Gordenin
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