Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow Print PDF (440K) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (34)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Sherman, D. A.
Right arrow Articles by Forsburg, S. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sherman, D. A.
Right arrow Articles by Forsburg, S. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, Vol 26, Issue 17 3955-3960, Copyright © 1998 by Oxford University Press

ARTICLES

Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p)

DA Sherman and SL Forsburg
Molecular Biology and Virology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla,CA 92037, USA.

MCM proteins are required for the proper regulation of DNA replication. There are six MCM proteins in all eukaryotes which interact to form a large complex. We report the cloning of fission yeast mcm3 +. mcm3 + is essential and spores carrying a Delta mcm3 disruption arrest with an apparently replicated DNA content. The protein is found constitutively in the nucleus and levels remain constant throughout the cell cycle. Mcm3p binds particularly tightly to Nda4p (Mcm5p), but is loosely associated with the other Schizosaccharomyces pombe MCM proteins. Thus, Mcm3p is a peripheral MCM subunit.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Plant Physiol.Home page
R. W. Shultz, T.-J. Lee, G. C. Allen, W. F. Thompson, and L. Hanley-Bowdoin
Dynamic Localization of the DNA Replication Proteins MCM5 and MCM7 in Plants
Plant Physiology, June 1, 2009; 150(2): 658 - 669.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. M. Kanter, I. Bruck, and D. L. Kaplan
Mcm Subunits Can Assemble into Two Different Active Unwinding Complexes
J. Biol. Chem., November 7, 2008; 283(45): 31172 - 31182.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. V. Mitkova, E. E. Biswas-Fiss, and S. B. Biswas
Modulation of DNA Synthesis in Saccharomyces cerevisiae Nuclear Extract by DNA Polymerases and the Origin Recognition Complex
J. Biol. Chem., February 25, 2005; 280(8): 6285 - 6292.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
P. Francon, J.-M. Lemaitre, C. Dreyer, D. Maiorano, O. Cuvier, and M. Mechali
A hypophosphorylated form of RPA34 is a specific component of pre-replication centers
J. Cell Sci., October 1, 2004; 117(21): 4909 - 4920.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
Y. Yamada, T. Nakagawa, and H. Masukata
A Novel Intermediate in Initiation Complex Assembly for Fission Yeast DNA Replication
Mol. Biol. Cell, August 1, 2004; 15(8): 3740 - 3750.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. A. Hodson, J. M. Bailis, and S. L. Forsburg
Efficient labeling of fission yeast Schizosaccharomyces pombe with thymidine and BUdR
Nucleic Acids Res., November 1, 2003; 31(21): e134 - e134.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. J. Davey, C. Indiani, and M. O'Donnell
Reconstitution of the Mcm2-7p Heterohexamer, Subunit Arrangement, and ATP Site Architecture
J. Biol. Chem., February 7, 2003; 278(7): 4491 - 4499.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Lei, I. H. Cheng, L. A. Roberts, M. A. McAlear, and B. K. Tye
Two mcm3 Mutations Affect Different Steps in the Initiation of DNA Replication
J. Biol. Chem., August 16, 2002; 277(34): 30824 - 30831.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
E. B. Gomez, M. G. Catlett, and S. L. Forsburg
Different Phenotypes in Vivo Are Associated With ATPase Motif Mutations in Schizosaccharomyces pombe Minichromosome Maintenance Proteins
Genetics, April 1, 2002; 160(4): 1305 - 1318.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F. Carpentieri, M. De Felice, M. De Falco, M. Rossi, and F. M. Pisani
Physical and Functional Interaction between the Mini-chromosome Maintenance-like DNA Helicase and the Single-stranded DNA Binding Protein from the Crenarchaeon Sulfolobus solfataricus
J. Biol. Chem., March 29, 2002; 277(14): 12118 - 12127.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
D. T. Liang and S. L. Forsburg
Characterization of Schizosaccharomyces pombe mcm7+ and cdc23+ (MCM10) and Interactions With Replication Checkpoints
Genetics, October 1, 2001; 159(2): 471 - 486.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
A. Vas, W. Mok, and J. Leatherwood
Control of DNA Rereplication via Cdc2 Phosphorylation Sites in the Origin Recognition Complex
Mol. Cell. Biol., September 1, 2001; 21(17): 5767 - 5777.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J.-K. Lee and J. Hurwitz
Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures
PNAS, January 2, 2001; 98(1): 54 - 59.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Maiorano, J.-M. Lemaitre, and M. Mechali
Stepwise Regulated Chromatin Assembly of MCM2-7 Proteins
J. Biol. Chem., March 17, 2000; 275(12): 8426 - 8431.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. A. Prokhorova and J. J. Blow
Sequential MCM/P1 Subcomplex Assembly Is Required to Form a Heterohexamer with Replication Licensing Activity
J. Biol. Chem., January 28, 2000; 275(4): 2491 - 2498.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
Z. You, Y. Komamura, and Y. Ishimi
Biochemical Analysis of the Intrinsic Mcm4-Mcm6-Mcm7 DNA Helicase Activity
Mol. Cell. Biol., December 1, 1999; 19(12): 8003 - 8015.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
S. G. Pasion and S. L. Forsburg
Nuclear Localization of Schizosaccharomyces pombe Mcm2/Cdc19p Requires MCM Complex Assembly
Mol. Biol. Cell, December 1, 1999; 10(12): 4043 - 4057.
[Abstract] [Full Text]

Home page
 GeneticsHome page
H. A. Snaith and S. L. Forsburg
Rereplication Phenomenon in Fission Yeast Requires MCM Proteins and Other S Phase Genes
Genetics, July 1, 1999; 152(3): 839 - 851.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
B. T. Roberts, C. Y. Ying, J. Gautier, and J. L. Maller
DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase
PNAS, March 16, 1999; 96(6): 2800 - 2804.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
D. Liang, J. Hodson, and S. Forsburg
Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay
J. Cell Sci., January 2, 1999; 112(4): 559 - 567.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
D. F. Shechter, C. Y. Ying, and J. Gautier
The Intrinsic DNA Helicase Activity of Methanobacterium thermoautotrophicum Delta H Minichromosome Maintenance Protein
J. Biol. Chem., May 12, 2000; 275(20): 15049 - 15059.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J.-K. Lee and J. Hurwitz
Isolation and Characterization of Various Complexes of the Minichromosome Maintenance Proteins of Schizosaccharomyces pombe
J. Biol. Chem., June 16, 2000; 275(25): 18871 - 18878.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Uchiyama, D. Griffiths, K.-i. Arai, and H. Masai
Essential Role of Sna41/Cdc45 in Loading of DNA Polymerase alpha onto Minichromosome Maintenance Proteins in Fission Yeast
J. Biol. Chem., July 6, 2001; 276(28): 26189 - 26196.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.