Nucleic Acids Research, Vol 27, Issue 1 209-212, Copyright © 1999 by Oxford University Press
MP Lefranc, V Giudicelli, C Ginestoux, J Bodmer, W Muller, R Bontrop, M Lemaitre, A Malik, V Barbie and D Chaume
IMGT, the international ImMunoGeneTics database (http://imgt.cnusc.
fr:8104), is a high-quality integrated database specialising in
Immunoglobulins (Ig), T cell Receptors (TcR) and Major Histocompatibility
Complex (MHC) molecules of all vertebrate species, created in 1989 by
Marie-Paule Lefranc, Universite Montpellier II, CNRS, Montpellier, France
(lefranc@ligm.igh.cnrs.fr). IMGT comprises three databases: LIGM-DB, a
comprehensive database of Ig and TcR, MHC/HLA-DB, and PRIMER-DB (the last
two in development); a tool, IMGT/DNAPLOT, developed for sequence analysis
and alignments; and expertised data based on the IMGT scientific chart, the
IMGT repertoire. By its high quality and its easy data distribution, IMGT
has important implications in medical research (repertoire in autoimmune
diseases, AIDS, leukemias, lymphomas), therapeutic approaches (antibody
engineering), genome diversity and genome evolution studies. IMGT is freely
available at http://imgt.cnusc. fr:8104
ARTICLES
IMGT, the international ImMunoGeneTics database
Laboratoire d'ImmunoGenetique Moleculaire, Universite Montpellier II, UPR CNRS 1142 IGH, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France. lefranc@ligm.igh.cnrs.fr
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  V. Venturi, H. Y. Chin, D. A. Price, D. C. Douek, and M. P. Davenport The Role of Production Frequency in the Sharing of Simian Immunodeficiency Virus-Specific CD8+ TCRs between Macaques J. Immunol., August 15, 2008; 181(4): 2597 - 2609. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kurosu, Y. Takiguchi, O. Okada, N. Yumoto, S. Sakao, Y. Tada, Y. Kasahara, N. Tanabe, K. Tatsumi, M. Weiden, et al. Identification of Annexin 1 as a Novel Autoantigen in Acute Exacerbation of Idiopathic Pulmonary Fibrosis J. Immunol., July 1, 2008; 181(1): 756 - 767. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. O. Abdalla, P. Kokhaei, L. Hansson, H. Mellstedt, and A. Osterborg Idiotype vaccination in patients with myeloma reduced circulating myeloma cells (CMC) Ann. Onc., June 1, 2008; 19(6): 1172 - 1179. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Lim, B. Lemercier, X. Wertz, S. L. Pottier, F. Huetz, and P. Kourilsky Many human peripheral VH5-expressing IgM+ B cells display a unique heavy-chain rearrangement Int. Immunol., January 1, 2008; 20(1): 105 - 116. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. B. Day, W. Zeng, P. C. Doherty, D. C. Jackson, K. Kedzierska, and S. J. Turner The Context of Epitope Presentation Can Influence Functional Quality of Recalled Influenza A Virus-Specific Memory CD8+ T Cells J. Immunol., August 15, 2007; 179(4): 2187 - 2194. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Retter, C. Chevillard, M. Scharfe, A. Conrad, M. Hafner, T.-H. Im, M. Ludewig, G. Nordsiek, S. Severitt, S. Thies, et al. Sequence and Characterization of the Ig Heavy Chain Constant and Partial Variable Region of the Mouse Strain 129S1 J. Immunol., August 15, 2007; 179(4): 2419 - 2427. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-C. Hsu, Y. Wu, P. Yang, Q. Wu, G. Job, J. Chen, J. Wang, M. A. V. Accavitti-Loper, W. E. Grizzle, R. H. Carter, et al. Overexpression of Activation-Induced Cytidine Deaminase in B Cells Is Associated with Production of Highly Pathogenic Autoantibodies J. Immunol., April 15, 2007; 178(8): 5357 - 5365. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Ohm-Laursen and T. Barington Analysis of 6912 Unselected Somatic Hypermutations in Human VDJ Rearrangements Reveals Lack of Strand Specificity and Correlation between Phase II Substitution Rates and Distance to the Nearest 3' Activation-Induced Cytidine Deaminase Target J. Immunol., April 1, 2007; 178(7): 4322 - 4334. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Aublin, M. Ciofani, N. Willkomm, A. Hamrouni, A. L. Szymczak-Workman, T. Takahashi, Y. Sandjeu, P. Guillaume, D. A. A. Vignali, O. Michielin, et al. A Natural Structural Variant of the Mouse TCR beta-Chain Displays Intrinsic Receptor Function and Antigen Specificity J. Immunol., December 15, 2006; 177(12): 8587 - 8594. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. P. Wong, L. Li, J. A. Frelinger, and R. Tisch Early Autoimmune Destruction of Islet Grafts Is Associated with a Restricted Repertoire of IGRP-Specific CD8+ T Cells in Diabetic Nonobese Diabetic Mice J. Immunol., February 1, 2006; 176(3): 1637 - 1644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Yang, G. C. Waldbieser, and C. J. Lobb The Nucleotide Targets of Somatic Mutation and the Role of Selection in Immunoglobulin Heavy Chains of a Teleost Fish J. Immunol., February 1, 2006; 176(3): 1655 - 1667. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Giudicelli, P. Duroux, C. Ginestoux, G. Folch, J. Jabado-Michaloud, D. Chaume, and M.-P. Lefranc IMGT/LIGM-DB, the IMGT(R) comprehensive database of immunoglobulin and T cell receptor nucleotide sequences Nucleic Acids Res., January 1, 2006; 34(suppl_1): D781 - D784. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. R. McLean, O. A. Olsen, I. N. Watt, P. Rathanaswami, K. B. Leslie, J. S. Babcook, and J. W. Schrader Recognition of Human Cytomegalovirus by Human Primary Immunoglobulins Identifies an Innate Foundation to an Adaptive Immune Response J. Immunol., April 15, 2005; 174(8): 4768 - 4778. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. B. Koralov, T. I. Novobrantseva, K. Hochedlinger, R. Jaenisch, and K. Rajewsky Direct in vivo VH to JH rearrangement violating the 12/23 rule J. Exp. Med., February 7, 2005; 201(3): 341 - 348. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Retter, H. H. Althaus, R. Munch, and W. Muller VBASE2, an integrative V gene database Nucleic Acids Res., January 1, 2005; 33(suppl_1): D671 - D674. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. R. Kolar, T. Yokota, M. I. D. Rossi, S. K. Nath, and J. D. Capra Human fetal, cord blood, and adult lymphocyte progenitors have similar potential for generating B cells with a diverse immunoglobulin repertoire Blood, November 1, 2004; 104(9): 2981 - 2987. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Zhou, K. R. Lottenbach, S. J. Barenkamp, and D. C. Reason Somatic Hypermutation and Diverse Immunoglobulin Gene Usage in the Human Antibody Response to the Capsular Polysaccharide of Streptococcus pneumoniae Type 6B Infect. Immun., June 1, 2004; 72(6): 3505 - 3514. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kurosu, M. D. Weiden, Y. Takiguchi, W. N. Rom, N. Yumoto, J. Jaishree, K. Nakata, Y. Kasahara, N. Tanabe, K. Tatsumi, et al. BCL-6 Mutations in Pulmonary Lymphoproliferative Disorders: Demonstration of an Aberrant Immunological Reaction in HIV-Related Lymphoid Interstitial Pneumonia J. Immunol., June 1, 2004; 172(11): 7116 - 7122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. F. Brady, K. L. Congdon, A. G. Clark, F. N. A. Sackey, E. H. Rudolph, M. Z. Radic, and M. H. Foster {kappa} Editing Rescues Autoreactive B Cells Destined for Deletion in Mice Transgenic for a Dual Specific Anti-Laminin Ig J. Immunol., May 1, 2004; 172(9): 5313 - 5321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. M. Collins, M. Ikutani, D. Puiu, G. A. Buck, A. Nadkarni, and B. Gaeta Partitioning of Rearranged Ig Genes by Mutation Analysis Demonstrates D-D Fusion and V Gene Replacement in the Expressed Human Repertoire J. Immunol., January 1, 2004; 172(1): 340 - 348. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-C. Gelly, J. Gracy, Q. Kaas, D. Le-Nguyen, A. Heitz, and L. Chiche The KNOTTIN website and database: a new information system dedicated to the knottin scaffold Nucleic Acids Res., January 1, 2004; 32(90001): D156 - 159. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Fecteau and S. Neron CD40 Stimulation of Human Peripheral B Lymphocytes: Distinct Response from Naive and Memory Cells J. Immunol., November 1, 2003; 171(9): 4621 - 4629. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Lieby, A. Soley, A.-M. Knapp, M. Cerutti, J.-M. Freyssinet, J.-L. Pasquali, and T. Martin Memory B cells producing somatically mutated antiphospholipid antibodies are present in healthy individuals Blood, October 1, 2003; 102(7): 2459 - 2465. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. H. Walsh, M. Thorselius, A. Johnson, O. Soderberg, M. Jerkeman, E. Bjorck, I. Eriksson, U. Thunberg, O. Landgren, M. Ehinger, et al. Mutated VH genes and preferential VH3-21 use define new subsets of mantle cell lymphoma Blood, May 15, 2003; 101(10): 4047 - 4054. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Wingren, A. B. Edmundson, and C. A.K. Borrebaeck Designing proteins to crystallize through {beta}-strand pairing Protein Eng. Des. Sel., April 1, 2003; 16(4): 255 - 264. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-P. Lefranc IMGT, the international ImMunoGeneTics database(R) Nucleic Acids Res., January 1, 2003; 31(1): 307 - 310. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Burioni, Y. Matsuura, N. Mancini, H. Tani, T. Miyamura, P. E. Varaldo, and M. Clementi Diverging Effects of Human Recombinant Anti-Hepatitis C Virus (HCV) Antibody Fragments Derived from a Single Patient on the Infectivity of a Vesicular Stomatitis Virus/HCV Pseudotype J. Virol., October 11, 2002; 76(22): 11775 - 11779. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. G. Noordzij, S. de Bruin-Versteeg, N. S. Verkaik, J. M. J. J. Vossen, R. de Groot, E. Bernatowska, A. W. Langerak, D. C. van Gent, and J. J. M. van Dongen The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins Blood, August 28, 2002; 100(6): 2145 - 2152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Zhou, K. R. Lottenbach, S. J. Barenkamp, A. H. Lucas, and D. C. Reason Recurrent Variable Region Gene Usage and Somatic Mutation in the Human Antibody Response to the Capsular Polysaccharide of Streptococcus pneumoniae Type 23F Infect. Immun., August 1, 2002; 70(8): 4083 - 4091. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Su, V. K. Nguyen, and M. Nei Adaptive Evolution of Variable Region Genes Encoding an Unusual Type of Immunoglobulin in Camelids Mol. Biol. Evol., March 1, 2002; 19(3): 205 - 215. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Chapal, T. Chardes, D. Bresson, M. Pugniere, J.-C. Mani, B. Pau, M. Bouanani, and S. Peraldi-Roux Thyroid Peroxidase Autoantibodies Obtained from Random Single Chain Fv Libraries Contain the Same Heavy/Light Chain Combinations as Occur in Vivo Endocrinology, November 1, 2001; 142(11): 4740 - 4750. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. S. Gricks, E. Rawlings, L. Foroni, J. A. Madrigal, and P. L. Amlot Somatically Mutated Regions of Immunoglobulin on Human B-Cell Lymphomas Code for Peptides That Bind to Autologous Major Histocompatibility Complex Class I, Providing a Potential Target for Cytotoxic T Cells Cancer Res., July 1, 2001; 61(13): 5145 - 5152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Lieby, A. Soley, H. Levallois, B. Hugel, J.-M. Freyssinet, M. Cerutti, J.-L. Pasquali, and T. Martin The clonal analysis of anticardiolipin antibodies in a single patient with primary antiphospholipid syndrome reveals an extreme antibody heterogeneity Blood, June 15, 2001; 97(12): 3820 - 3828. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Y. Mortuza, I. M. Moreira, M. Papaioannou, P. Gameiro, L. A. Coyle, C. S. Gricks, P. Amlot, H. G. Prentice, A. Madrigal, A. V. Hoffbrand, et al. Immunoglobulin heavy-chain gene rearrangement in adult acute lymphoblastic leukemia reveals preferential usage of JH-proximal variable gene segments Blood, May 1, 2001; 97(9): 2716 - 2726. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. van der Burg, T. Tumkaya, M. Boerma, S. de Bruin-Versteeg, A. W. Langerak, and J. J. M. van Dongen Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus Blood, February 15, 2001; 97(4): 1001 - 1008. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-P. Lefranc IMGT, the international ImMunoGeneTics database Nucleic Acids Res., January 1, 2001; 29(1): 207 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P B Furtado, R Furmonaviciene, J McElveen, H F Sewell, and F Shakib Prediction of the interacting surfaces in a trimolecular complex formed between the major dust mite allergen Der p 1, a mouse monoclonal anti-Der p 1 antibody, and its anti-idiotype Mol. Pathol., December 1, 2000; 53(6): 324 - 332. [Abstract] [Full Text]
|
|
|
|
|
|
P. M. Dammers, A. Visser, E. R. Popa, P. Nieuwenhuis, and F. G. M. Kroese Most Marginal Zone B Cells in Rat Express Germline Encoded Ig VH Genes and Are Ligand Selected J. Immunol., December 1, 2000; 165(11): 6156 - 6169. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Polakova, D. Plaksin, D. H. Chung, I. M. Belyakov, J. A. Berzofsky, and D. H. Margulies Antibodies Directed Against the MHC-I Molecule H-2Dd Complexed with an Antigenic Peptide: Similarities to a T Cell Receptor with the Same Specificity J. Immunol., November 15, 2000; 165(10): 5703 - 5712. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. G. Noordzij, N. S. Verkaik, N. G. Hartwig, R. de Groot, D. C. van Gent, and J. J. M. van Dongen N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements Blood, July 1, 2000; 96(1): 203 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. C. Wilson, K. Wilson, Y.-J. Liu, J. Banchereau, V. Pascual, and J. D. Capra Receptor Revision of Immunoglobulin Heavy Chain Variable Region Genes in Normal Human B Lymphocytes J. Exp. Med., May 30, 2000; 191(11): 1881 - 1894. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
, , , , , , , , , and Human Anti-Thyroid Peroxidase Single-Chain Fragment Variable of Ig Isolated from a Combinatorial Library Assembled In-Cell: Insights into the In Vivo J. Immunol., April 15, 2000; 164(8): 4162 - 4169. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Fasching, S. Panzer, O. A. Haas, R. Marschalek, H. Gadner, and E. R. Panzer-Grumayer Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia Blood, April 15, 2000; 95(8): 2722 - 2724. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Karlstrom, G. Zhong, C. Rader, N. A. Larsen, A. Heine, R. Fuller, B. List, F. Tanaka, I. A. Wilson, C. F. Barbas III, et al. Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task PNAS, April 11, 2000; 97(8): 3878 - 3883. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ruiz, V. Giudicelli, C. Ginestoux, P. Stoehr, J. Robinson, J. Bodmer, S. G. E. Marsh, R. Bontrop, M. Lemaitre, G. Lefranc, et al. IMGT, the international ImMunoGeneTics database Nucleic Acids Res., January 1, 2000; 28(1): 219 - 221. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Schonbach, J. L.Y. Koh, X. Sheng, L. Wong, and V. Brusic FIMM, a database of functional molecular immunology Nucleic Acids Res., January 1, 2000; 28(1): 222 - 224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. C. Nicholson, X. Zou, A. V. Popov, G. P. Cook, E. M. Corps, S. Humphries, C. Ayling, B. Goyenechea, J. Xian, M. J. Taussig, et al. Antibody Repertoires of Four- and Five-Feature Translocus Mice Carrying Human Immunoglobulin Heavy Chain and {kappa} and {lambda} Light Chain Yeast Artificial Chromosomes J. Immunol., December 15, 1999; 163(12): 6898 - 6906. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Su and M. Nei Fifty-million-year-old polymorphism at an immunoglobulin variable region gene locus in the rabbit evolutionary lineage PNAS, August 17, 1999; 96(17): 9710 - 9715. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Pongers-Willemse, A. W. Langerak, W. A. Harts, A. J.M. Wijkhuijs, E. R. van Wering, and J. J.M. van Dongen Ig Heavy Chain Gene Rearrangements in T-Cell Acute Lymphoblastic Leukemia Exhibit Predominant DH6-19 and DH7-27 Gene Usage, Can Result in Complete V-D-J Rearrangements, and Are Rare in T-Cell Receptor alpha beta Lineage Blood, June 15, 1999; 93(12): 4079 - 4085. [Abstract] [Full Text] [PDF]
|
|