Nucleic Acids Research, Vol 27, Issue 3 711-720, Copyright © 1999 by Oxford University Press
AP Wolffe and JJ Hayes
Chromatin disruption and modification are associated with transcriptional
regulation by diverse coactivators and corepressors. Here we discuss the
possible structural basis and functional consequences of the observed
alterations in chromatin associated with transcriptional activation and
repression. Recent advances in defining the roles of individual histones
and their domains in the assembly and maintenance of regulatory
architectures provide a framework for understanding how chromatin
remodelling machines, histone acetyltransferases and deacetylases function.
REVIEWS
Chromatin disruption and modification
Laboratory of Molecular Embryology, Natational Institute of Child Health and Human Development, NIH, Building 18T, Room 106, Bethesda, MD 20892-5431, USA. awlme@helix.nih.gov
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  R. Nag, M. Kyriss, J. W. Smerdon, J. J. Wyrick, and M. J. Smerdon A cassette of N-terminal amino acids of histone H2B are required for efficient cell survival, DNA repair and Swi/Snf binding in UV irradiated yeast Nucleic Acids Res., March 1, 2010; 38(5): 1450 - 1460. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Vandermeers, P. Hubert, P. Delvenne, C. Mascaux, B. Grigoriu, A. Burny, A. Scherpereel, and L. Willems Valproate, in Combination with Pemetrexed and Cisplatin, Provides Additional Efficacy to the Treatment of Malignant Mesothelioma Clin. Cancer Res., April 15, 2009; 15(8): 2818 - 2828. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kinner, W. Wu, C. Staudt, and G. Iliakis {gamma}-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin Nucleic Acids Res., October 1, 2008; 36(17): 5678 - 5694. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. H. Smith, T. A. Kohn, A. K. Chetty, and E. O. Ojuka CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene Am J Physiol Endocrinol Metab, September 1, 2008; 295(3): E698 - E704. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Guo, J. Zhou, A. A. Elling, J.-B. F. Charron, and X. W. Deng Histone Modifications and Expression of Light-Regulated Genes in Arabidopsis Are Cooperatively Influenced by Changing Light Conditions Plant Physiology, August 1, 2008; 147(4): 2070 - 2083. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Gad and Y. Kim A viral histone H4 encoded by Cotesia plutellae bracovirus inhibits haemocyte-spreading behaviour of the diamondback moth, Plutella xylostella J. Gen. Virol., April 1, 2008; 89(4): 931 - 938. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Fink, D. Imholz, and F. Thoma Contribution of the Serine 129 of Histone H2A to Chromatin Structure Mol. Cell. Biol., May 15, 2007; 27(10): 3589 - 3600. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Gilbert, I. Thomson, S. Boyle, J. Allan, B. Ramsahoye, and W. A. Bickmore DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction J. Cell Biol., May 7, 2007; 177(3): 401 - 411. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Mihardja, A. J. Spakowitz, Y. Zhang, and C. Bustamante Effect of force on mononucleosomal dynamics PNAS, October 24, 2006; 103(43): 15871 - 15876. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Fukuda, N. Sano, S. Muto, and M. Horikoshi Simple histone acetylation plays a complex role in the regulation of gene expression. Briefings in Functional Genomics, September 1, 2006; 5(3): 190 - 208. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C Bossard, A Jarry, C Colombeix, K Bach-Ngohou, A Moreau, D Loussouarn, J-F Mosnier, and C L Laboisse Phosphohistone H3 labelling for histoprognostic grading of breast adenocarcinomas and computer-assisted determination of mitotic index J. Clin. Pathol., July 1, 2006; 59(7): 706 - 710. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Okada, P. L. Bhalla, and M. B. Singh Expressed Sequence Tag Analysis of Lilium longiflorum Generative Cells Plant Cell Physiol., June 1, 2006; 47(6): 698 - 705. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. K. Sims, S. I. Houston, T. Magazinnik, and J. C. Rice A Trans-tail Histone Code Defined by Monomethylated H4 Lys-20 and H3 Lys-9 Demarcates Distinct Regions of Silent Chromatin J. Biol. Chem., May 5, 2006; 281(18): 12760 - 12766. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. H. Kramer, D. Baus, S. K. Knauer, S. Stein, E. Jager, R. H. Stauber, M. Grez, E. Pfitzner, and T. Heinzel Acetylation of Stat1 modulates NF-{kappa}B activity. Genes & Dev., February 15, 2006; 20(4): 473 - 485. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. M. Svedruzic, C. Wang, J. V. Kosmoski, and M. J. Smerdon Accommodation and Repair of a UV Photoproduct in DNA at Different Rotational Settings on the Nucleosome Surface J. Biol. Chem., December 2, 2005; 280(48): 40051 - 40057. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. K. Adhvaryu, S. A. Morris, B. D. Strahl, and E. U. Selker Methylation of Histone H3 Lysine 36 Is Required for Normal Development in Neurospora crassa Eukaryot. Cell, August 1, 2005; 4(8): 1455 - 1464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Xiao, C. Jing, G. Kelly, P. A. Walker, F. W. Muskett, T. A. Frenkiel, S. R. Martin, K. Sarma, D. Reinberg, S. J. Gamblin, et al. Specificity and mechanism of the histone methyltransferase Pr-Set7 Genes & Dev., June 15, 2005; 19(12): 1444 - 1454. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P.-O. Esteve, D. Patnaik, H. G. Chin, J. Benner, M. A. Teitell, and S. Pradhan Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase Nucleic Acids Res., June 6, 2005; 33(10): 3211 - 3223. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. F. Dion, S. J. Altschuler, L. F. Wu, and O. J. Rando From the Cover: Genomic characterization reveals a simple histone H4 acetylation code PNAS, April 12, 2005; 102(15): 5501 - 5506. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H K Kinyamu, J Chen, and T K Archer Linking the ubiquitin-proteasome pathway to chromatin remodeling/modification by nuclear receptors J. Mol. Endocrinol., April 1, 2005; 34(2): 281 - 297. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. G. Cosio, B. Mann, K. Ito, E. Jazrawi, P. J. Barnes, K. F. Chung, and I. M. Adcock Histone Acetylase and Deacetylase Activity in Alveolar Macrophages and Blood Mononocytes in Asthma Am. J. Respir. Crit. Care Med., July 15, 2004; 170(2): 141 - 147. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Martin, D. J. Pouchnik, J. L. Walker, and J. J. Wyrick Redundant Roles for Histone H3 N-Terminal Lysine Residues in Subtelomeric Gene Repression in Saccharomyces cerevisiae Genetics, July 1, 2004; 167(3): 1123 - 1132. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Chambeyron and W. A. Bickmore Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription Genes & Dev., May 15, 2004; 18(10): 1119 - 1130. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Jeong, L. K. Adamson, D. G. Greenhalgh, and K. Cho Injury-Associated Differential Regulation of Histone Expression and Modification in the Thymus of Mice Exp Biol Med, April 1, 2004; 229(4): 327 - 334. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Ferreiro, N. G. Powell, N. Karabetsou, N. A. Kent, J. Mellor, and R. Waters Cbf1p modulates chromatin structure, transcription and repair at the Saccharomyces cerevisiae MET16 locus Nucleic Acids Res., March 8, 2004; 32(5): 1617 - 1626. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. Katz, J. G. Bornstein, E. Lasek-Nesselquist, and S. V. Muse Dramatic Diversity of Ciliate Histone H4 Genes Revealed by Comparisons of Patterns of Substitutions and Paralog Divergences Among Eukaryotes Mol. Biol. Evol., March 1, 2004; 21(3): 555 - 562. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Chen, Z. Peng, and E. Bateman In vivo interactions of the Acanthamoeba TBP gene promoter Nucleic Acids Res., February 19, 2004; 32(4): 1251 - 1260. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Vitolo, Z. Yang, R. Basavappa, and J. J. Hayes Structural Features of Transcription Factor IIIA Bound to a Nucleosome in Solution Mol. Cell. Biol., January 15, 2004; 24(2): 697 - 707. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W.A. BICKMORE, N.L. MAHY, and S. CHAMBEYRON Do Higher-Order Chromatin Structure and Nuclear Reorganization Play a Role in Regulating Hox Gene Expression during Development? Cold Spring Harb Symp Quant Biol, January 1, 2004; 69(0): 251 - 258. [Abstract] [PDF]
|
|
|
|
|
|
E.-J. Park, D. W. Chan, J.-H. Park, M. A. Oettinger, and J. Kwon DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner Nucleic Acids Res., December 1, 2003; 31(23): 6819 - 6827. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Aoyagi, P. A. Wade, and J. J. Hayes Nucleosome Sliding Induced by the xMi-2 Complex Does Not Occur Exclusively via a Simple Twist-diffusion Mechanism J. Biol. Chem., August 15, 2003; 278(33): 30562 - 30568. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Fujii, R. Z. Luo, J. Yuan, M. Kadota, M. Oshimura, S. R. Dent, Y. Kondo, J.-P. J. Issa, R. C. Bast Jr, and Y. Yu Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation Hum. Mol. Genet., August 1, 2003; 12(15): 1791 - 1800. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. L. Chua, L. A. Watson, and J. C. Gray The Transcriptional Enhancer of the Pea Plastocyanin Gene Associates with the Nuclear Matrix and Regulates Gene Expression through Histone Acetylation PLANT CELL, June 1, 2003; 15(6): 1468 - 1479. [Abstract] [Full Text]
|
|
|
|
|
|
Q. Ren and M. A. Gorovsky The Nonessential H2A N-Terminal Tail Can Function as an Essential Charge Patch on the H2A.Z Variant N-Terminal Tail Mol. Cell. Biol., April 15, 2003; 23(8): 2778 - 2789. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Zhang and C. T. Teng Phosphorylation of Kruppel-like factor 5 (KLF5/IKLF) at the CBP interaction region enhances its transactivation function Nucleic Acids Res., April 15, 2003; 31(8): 2196 - 2208. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. J. Kraker, C. A. Mizzen, B. G. Hartl, J. Miin, C. D. Allis, and R. L. Merriman Modulation of Histone Acetylation by [4-(Acetylamino)-N-(2-Amino-phenyl) Benzamide] in HCT-8 Colon Carcinoma Mol. Cancer Ther., April 1, 2003; 2(4): 401 - 408. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Zhang, Y. Wang, J. Long, J. Girton, J. Johansen, and K. M. Johansen A Developmentally Regulated Splice Variant from the Complex lola Locus Encoding Multiple Different Zinc Finger Domain Proteins Interacts with the Chromosomal Kinase JIL-1 J. Biol. Chem., March 21, 2003; 278(13): 11696 - 11704. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Aoyagi and J. J. Hayes hSWI/SNF-Catalyzed Nucleosome Sliding Does Not Occur Solely via a Twist-Diffusion Mechanism Mol. Cell. Biol., November 1, 2002; 22(21): 7484 - 7490. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Guillebault, S. Sasorith, E. Derelle, J.-M. Wurtz, J.-C. Lozano, S. Bingham, L. Tora, and H. Moreau A New Class of Transcription Initiation Factors, Intermediate between TATA Box-binding Proteins (TBPs) and TBP-like Factors (TLFs), Is Present in the Marine Unicellular Organism, the Dinoflagellate Crypthecodinium cohnii J. Biol. Chem., October 18, 2002; 277(43): 40881 - 40886. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E. Sterner, R. Belotserkovskaya, and S. L. Berger SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription PNAS, September 3, 2002; 99(18): 11622 - 11627. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Ito and M. Bustin Immunohistochemical Localization of the Nucleosome-Binding Protein HMGN3 in Mouse Brain J. Histochem. Cytochem., September 1, 2002; 50(9): 1273 - 1275. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Rice, K. Nishioka, K. Sarma, R. Steward, D. Reinberg, and C. D. Allis Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes Genes & Dev., September 1, 2002; 16(17): 2225 - 2230. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Li, Q. Lin, H.-G. Yoon, Z.-Q. Huang, B. D. Strahl, C. D. Allis, and J. Wong Involvement of Histone Methylation and Phosphorylation in Regulation of Transcription by Thyroid Hormone Receptor Mol. Cell. Biol., August 15, 2002; 22(16): 5688 - 5697. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. D. Hollenbach, C. J. McPherson, E. J. Mientjes, R. Iyengar, and G. Grosveld Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek J. Cell Sci., August 15, 2002; 115(16): 3319 - 3330. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Tulin, D. Stewart, and A. C. Spradling The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development Genes & Dev., August 15, 2002; 16(16): 2108 - 2119. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Aoyagi, G. Narlikar, C. Zheng, S. Sif, R. E. Kingston, and J. J. Hayes Nucleosome Remodeling by the Human SWI/SNF Complex Requires Transient Global Disruption of Histone-DNA Interactions Mol. Cell. Biol., June 1, 2002; 22(11): 3653 - 3662. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-H. Lim, M. Bustin, V. V. Ogryzko, and Y. V. Postnikov Metastable Macromolecular Complexes Containing High Mobility Group Nucleosome-binding Chromosomal Proteins in HeLa Nuclei J. Biol. Chem., May 31, 2002; 277(23): 20774 - 20782. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Wilson, A. R. Ricci, B. J. Deroo, and T. K. Archer The Histone Deacetylase Inhibitor Trichostatin A Blocks Progesterone Receptor-mediated Transactivation of the Mouse Mammary Tumor Virus Promoter in Vivo J. Biol. Chem., April 19, 2002; 277(17): 15171 - 15181. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. K. Davie, R. J. Trumbly, and S. Y. R. Dent Histone-Dependent Association of Tup1-Ssn6 with Repressed Genes In Vivo Mol. Cell. Biol., February 1, 2002; 22(3): 693 - 703. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Asp, M. Wihlborg, M. Karlen, and A.-K. O. Farrants Expression of BRG1, a human SWI/SNF component, affects the organisation of actin filaments through the RhoA signalling pathway J. Cell Sci., January 7, 2002; 115(13): 2735 - 2746. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. C. Bash, J. Yodh, Y. Lyubchenko, N. Woodbury, and D. Lohr Population Analysis of Subsaturated 172-12 Nucleosomal Arrays by Atomic Force Microscopy Detects Nonrandom Behavior That Is Favored by Histone Acetylation and Short Repeat Length J. Biol. Chem., December 14, 2001; 276(51): 48362 - 48370. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Loyola, G. LeRoy, Y.-H. Wang, and D. Reinberg Reconstitution of recombinant chromatin establishes a requirement for histone-tail modifications during chromatin assembly and transcription Genes & Dev., November 1, 2001; 15(21): 2837 - 2851. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Hirschler-Laszkiewicz, A. Cavanaugh, Q. Hu, J. Catania, M. L. Avantaggiati, and L. I. Rothblum The role of acetylation in rDNA transcription Nucleic Acids Res., October 15, 2001; 29(20): 4114 - 4124. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Thiriet and J. J. Hayes A novel labeling technique reveals a function for histone H2A/H2B dimer tail domains in chromatin assembly in vivo Genes & Dev., August 15, 2001; 15(16): 2048 - 2053. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. P. Chadwick, C. M. Valley, and H. F. Willard Histone variant macroH2A contains two distinct macrochromatin domains capable of directing macroH2A to the inactive X chromosome Nucleic Acids Res., July 1, 2001; 29(13): 2699 - 2705. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kimura and P. R. Cook Kinetics of Core Histones in Living Human Cells: Little Exchange of H3 and H4 and Some Rapid Exchange of H2b J. Cell Biol., June 25, 2001; 153(7): 1341 - 1354. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Ma, P. Svoboda, R. M. Schultz, and P. Stein Regulation of Zygotic Gene Activation in the Preimplantation Mouse Embryo: Global Activation and Repression of Gene Expression Biol Reprod, June 1, 2001; 64(6): 1713 - 1721. [Abstract] [Full Text]
|
|
|
|
|
|
D. Angelov, J. M. Vitolo, V. Mutskov, S. Dimitrov, and J. J. Hayes Preferential interaction of the core histone tail domains with linker DNA PNAS, May 24, 2001; (2001) 121171498. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Wan, K. Zhao, S. S. J. Lee, and U. Francke MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome Hum. Mol. Genet., May 1, 2001; 10(10): 1085 - 1092. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. L. Chua, A. P. C. Brown, and J. C. Gray Targeted Histone Acetylation and Altered Nuclease Accessibility over Short Regions of the Pea Plastocyanin Gene PLANT CELL, March 1, 2001; 13(3): 599 - 612. [Abstract] [Full Text]
|
|
|
|
|
|
C.-Y. Gui and A. Dean Acetylation of a Specific Promoter Nucleosome Accompanies Activation of the {varepsilon}-Globin Gene by {beta}-Globin Locus Control Region HS2 Mol. Cell. Biol., February 15, 2001; 21(4): 1155 - 1163. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. A. Atienzar, V. V. Cheung, A. N. Jha, and M. H. Depledge Fitness Parameters and DNA Effects Are Sensitive Indicators of Copper-Induced Toxicity in Daphnia magna Toxicol. Sci., February 1, 2001; 59(2): 241 - 250. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. P. Chadwick and H. F. Willard A Novel Chromatin Protein, Distantly Related to Histone H2a, Is Largely Excluded from the Inactive X Chromosome J. Cell Biol., January 22, 2001; 152(2): 375 - 384. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. D. Urnov and A. P. Wolffe A Necessary Good: Nuclear Hormone Receptors and Their Chromatin Templates Mol. Endocrinol., January 1, 2001; 15(1): 1 - 16. [Full Text]
|
|
|
|
|
|
E. C. Forsberg, K. M. Downs, H. M. Christensen, H. Im, P. A. Nuzzi, and E. H. Bresnick Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain PNAS, December 19, 2000; 97(26): 14494 - 14499. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. U. Protacio, G. Li, P. T. Lowary, and J. Widom Effects of Histone Tail Domains on the Rate of Transcriptional Elongation through a Nucleosome Mol. Cell. Biol., December 1, 2000; 20(23): 8866 - 8878. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. A. Wiley, R. Ohba, M.-C. Yao, and C. D. Allis Developmentally Regulated Rpd3p Homolog Specific to the Transcriptionally Active Macronucleus of Vegetative Tetrahymena thermophila Mol. Cell. Biol., November 15, 2000; 20(22): 8319 - 8328. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Henderson, M. Bunce, N. Siddon, R. Reeves, and D. J. Tremethick High-Mobility-Group Protein I Can Modulate Binding of Transcription Factors to the U5 Region of the Human Immunodeficiency Virus Type 1 Proviral Promoter J. Virol., November 15, 2000; 74(22): 10523 - 10534. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Harbour and D. C. Dean The Rb/E2F pathway: expanding roles and emerging paradigms Genes & Dev., October 1, 2000; 14(19): 2393 - 2409. [Full Text]
|
|
|
|
 |
|
 D. A. Hume Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression Blood, October 1, 2000; 96(7): 2323 - 2328. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Dahiya, M. R. Gavin, R. X. Luo, and D. C. Dean Role of the LXCXE Binding Site in Rb Function Mol. Cell. Biol., September 15, 2000; 20(18): 6799 - 6805. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Chen, R. E. Baker, K. C. Keith, K. Harris, S. Stoler, and M. Fitzgerald-Hayes The N Terminus of the Centromere H3-Like Protein Cse4p Performs an Essential Function Distinct from That of the Histone Fold Domain Mol. Cell. Biol., September 15, 2000; 20(18): 7037 - 7048. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. G. V. Martini, R. Delage-Mourroux, D. M. Kraichely, and B. S. Katzenellenbogen Prothymosin Alpha Selectively Enhances Estrogen Receptor Transcriptional Activity by Interacting with a Repressor of Estrogen Receptor Activity Mol. Cell. Biol., September 1, 2000; 20(17): 6224 - 6232. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Rice and B. W. Futscher Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter Nucleic Acids Res., September 1, 2000; 28(17): 3233 - 3239. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Hemavathy, S. C. Guru, J. Harris, J. D. Chen, and Y. T. Ip Human Slug Is a Repressor That Localizes to Sites of Active Transcription Mol. Cell. Biol., July 15, 2000; 20(14): 5087 - 5095. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Jin, Y. Wang, J. Johansen, and K. M. Johansen Jil-1, a Chromosomal Kinase Implicated in Regulation of Chromatin Structure, Associates with the Male Specific Lethal (Msl) Dosage Compensation Complex J. Cell Biol., May 29, 2000; 149(5): 1005 - 1010. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Renaud, J. M. Harris, M. Downes, L. J. Burke, and G. E .O. Muscat Structure-Function Analysis of the Rev-erbA and RVR Ligand-Binding Domains Reveals a Large Hydrophobic Surface That Mediates Corepressor Binding and a Ligand Cavity Occupied by Side Chains Mol. Endocrinol., May 1, 2000; 14(5): 700 - 717. [Abstract] [Full Text]
|
|
|
|
|
|
J. E. Herrera, R. L. Schiltz, and M. Bustin The Accessibility of Histone H3 Tails in Chromatin Modulates Their Acetylation by P300/CBP-associated Factor J. Biol. Chem., April 21, 2000; 275(17): 12994 - 12999. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. L. de la Serna, K. A. Carlson, D. A. Hill, C. J. Guidi, R. O. Stephenson, S. Sif, R. E. Kingston, and A. N. Imbalzano Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene Mol. Cell. Biol., April 15, 2000; 20(8): 2839 - 2851. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Schoenmakers, G. Verrijdt, B. Peeters, G. Verhoeven, W. Rombauts, and F. Claessens Differences in DNA Binding Characteristics of the Androgen and Glucocorticoid Receptors Can Determine Hormone-specific Responses J. Biol. Chem., April 14, 2000; 275(16): 12290 - 12297. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q. Wang and K. E. Latham Translation of Maternal Messenger Ribonucleic Acids Encoding Transcription Factors During Genome Activation in Early Mouse Embryos Biol Reprod, April 1, 2000; 62(4): 969 - 978. [Abstract] [Full Text]
|
|
|
|
|
|
J. M. Vitolo, C. Thiriet, and J. J. Hayes The H3-H4 N-Terminal Tail Domains Are the Primary Mediators of Transcription Factor IIIA Access to 5S DNA within a Nucleosome Mol. Cell. Biol., March 15, 2000; 20(6): 2167 - 2175. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Shirakawa, D. Landsman, Y. V. Postnikov, and M. Bustin NBP-45, a Novel Nucleosomal Binding Protein with a Tissue-specific and Developmentally Regulated Expression J. Biol. Chem., February 25, 2000; 275(9): 6368 - 6374. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Ha, K. Hellauer, and B. Turcotte Fusions with histone H3 result in highly specific alteration of gene expression Nucleic Acids Res., February 15, 2000; 28(4): 1026 - 1035. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Robzyk, J. Recht, and M. A. Osley Rad6-Dependent Ubiquitination of Histone H2B in Yeast Science, January 21, 2000; 287(5452): 501 - 504. [Abstract] [Full Text]
|
|
|
|
|
|
J. E. Herrera, K. L. West, R. L. Schiltz, Y. Nakatani, and M. Bustin Histone H1 Is a Specific Repressor of Core Histone Acetylation in Chromatin Mol. Cell. Biol., January 15, 2000; 20(2): 523 - 529. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Mucha, K. Lisowska, A. Goc, and J. Filipski Nuclease-hypersensitive Chromatin Formed by a CpG Island in Human DNA Cloned as an Artificial Chromosome in Yeast J. Biol. Chem., January 14, 2000; 275(2): 1275 - 1278. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Volpi, E Chevret, T Jones, R Vatcheva, J Williamson, S Beck, R. Campbell, M Goldsworthy, S. Powis, J Ragoussis, et al. Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei J. Cell Sci., January 5, 2000; 113(9): 1565 - 1576. [Abstract] [PDF]
|
|
|
|
|
|
Y. Cui and C. Bustamante Pulling a single chromatin fiber reveals the forces that maintain its higher-order structure PNAS, January 4, 2000; 97(1): 127 - 132. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. R. Smith, A. Pannuti, W. Gu, A. Steurnagel, R. G. Cook, C. D. Allis, and J. C. Lucchesi The Drosophila MSL Complex Acetylates Histone H4 at Lysine 16, a Chromatin Modification Linked to Dosage Compensation Mol. Cell. Biol., January 1, 2000; 20(1): 312 - 318. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. D. Strahl, R. Ohba, R. G. Cook, and C. D. Allis Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena PNAS, December 21, 1999; 96(26): 14967 - 14972. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Y. Kwon, J. M. Park, B. S. Gim, S. J. Han, J. Lee, and Y.-J. Kim Caenorhabditis elegans Mediator complexes are required for developmental-specific transcriptional activation PNAS, December 21, 1999; 96(26): 14990 - 14995. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Zhang, S. K. Spratt, Q. Liu, B. Johnstone, H. Qi, E. E. Raschke, A. C. Jamieson, E. J. Rebar, A. P. Wolffe, and C. C. Case Synthetic Zinc Finger Transcription Factor Action at an Endogenous Chromosomal Site. ACTIVATION OF THE HUMAN ERYTHROPOIETIN GENE J. Biol. Chem., October 20, 2000; 275(43): 33850 - 33860. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. M. Christoffels, P. E. M. H. Habets, A. T. Das, D. E. W. Clout, M. A. van Roon, A. F. M. Moorman, and W. H. Lamers A Single Regulatory Module of the Carbamoylphosphate Synthetase I Gene Executes Its Hepatic Program of Expression J. Biol. Chem., December 15, 2000; 275(51): 40020 - 40027. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Gunjan, D. B. Sittman, and D. T. Brown Core Histone Acetylation Is Regulated by Linker Histone Stoichiometry in Vivo J. Biol. Chem., January 26, 2001; 276(5): 3635 - 3640. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Zhong, Y. Zhang, C. Jansen, H. Goto, M. Inagaki, and Z. Dong MAP Kinases Mediate UVB-induced Phosphorylation of Histone H3 at Serine 28 J. Biol. Chem., April 13, 2001; 276(16): 12932 - 12937. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P.-Q. Liu, E. J. Rebar, L. Zhang, Q. Liu, A. C. Jamieson, Y. Liang, H. Qi, P.-X. Li, B. Chen, M. C. Mendel, et al. Regulation of an Endogenous Locus Using a Panel of Designed Zinc Finger Proteins Targeted to Accessible Chromatin Regions. ACTIVATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR A J. Biol. Chem., March 30, 2001; 276(14): 11323 - 11334. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Hellauer, E. Sirard, and B. Turcotte Decreased Expression of Specific Genes in Yeast Cells Lacking Histone H1 J. Biol. Chem., April 20, 2001; 276(17): 13587 - 13592. [Abstract] [Full Text] [PDF]
|
|