Nucleic Acids Research, 2000, Vol. 28, No. 1 219-221
© 2000 Oxford University Press
IMGT, the international ImMunoGeneTics database
Laboratoire d’ImmunoGénétique Moléculaire, LIGM, UPR CNRS 1142 IGH, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France, 1EMBL Outstation EBI, Hinxton, UK, 2ICRF, Oxford, UK, 3ANRI, London, UK, 4BPRC, Rijswijk, The Netherlands and 5EUROGENTEC S.A., Seraing, Belgium
IMGT, the international ImMunoGeneTics database (http://imgt.cines.fr:8104 ), is a high-quality integrated database specialising in Immunoglobulins (Ig), T cell Receptors (TcR) and Major Histocompatibility Complex (MHC) molecules of all vertebrate species, created in 1989 by Marie-Paule Lefranc, Université Montpellier II, CNRS, Montpellier, France (lefranc@ ligm.igh.cnrs.fr ). At present, IMGT includes two databases: IMGT/LIGM-DB, a comprehensive database of Ig and TcR from human and other vertebrates, with translation for fully annotated sequences, and IMGT/HLA-DB, a database of the human MHC referred to as HLA (Human Leucocyte Antigens). The IMGT server provides a common access to expertized genomic, proteomic, structural and polymorphic data of Ig and TcR molecules of all vertebrates. By its high quality and its easy data distribution, IMGT has important implications in medical research (repertoire in autoimmune diseases, AIDS, leukemias, lymphomas), therapeutic approaches (antibody engineering), genome diversity and genome evolution studies. IMGT is freely available at http://imgt.cines.fr:8104 . The IMGT Index is provided at the IMGT Marie-Paule page (http://imgt.cines.fr:8104/textes/IMGTindex.html ).
* To whom correspondence should be addressed. Tel: +33 4 99 61 99 65; Fax: +33 4 99 61 99 01; Email: lefranc@ligm.igh.cnrs.fr
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. Tian, G. K. Luskin, K. M. Dischert, J. N. Higginbotham, B. E. Shepherd, and J. E. Crowe Jr Immunodominance of the VH1-46 Antibody Gene Segment in the Primary Repertoire of Human Rotavirus-Specific B Cells Is Reduced in the Memory Compartment through Somatic Mutation of Nondominant Clones J. Immunol., March 1, 2008; 180(5): 3279 - 3288. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. V. Williams, Z. Chen, G. Cseke, D. W. Wright, C. J. Keefer, S. J. Tollefson, A. Hessell, A. Podsiad, B. E. Shepherd, P. P. Sanna, et al. A Recombinant Human Monoclonal Antibody to Human Metapneumovirus Fusion Protein That Neutralizes Virus In Vitro and Is Effective Therapeutically In Vivo J. Virol., August 1, 2007; 81(15): 8315 - 8324. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Somma, G. Ristori, L. Battistini, S. Cannoni, G. Borsellino, A. Diamantini, M. Salvetti, R. Sorrentino, and M. T. Fiorillo Characterization of CD8+ T cell repertoire in identical twins discordant and concordant for multiple sclerosis J. Leukoc. Biol., March 1, 2007; 81(3): 696 - 710. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. P. Wong, L. Li, J. A. Frelinger, and R. Tisch Early Autoimmune Destruction of Islet Grafts Is Associated with a Restricted Repertoire of IGRP-Specific CD8+ T Cells in Diabetic Nonobese Diabetic Mice J. Immunol., February 1, 2006; 176(3): 1637 - 1644. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K. Singh, S. Srivastava, G.P.S. Raghava, and G. C. Varshney HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies Bioinformatics, January 15, 2006; 22(2): 253 - 255. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. B. Koralov, T. I. Novobrantseva, K. Hochedlinger, R. Jaenisch, and K. Rajewsky Direct in vivo VH to JH rearrangement violating the 12/23 rule J. Exp. Med., February 7, 2005; 201(3): 341 - 348. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Assaf, M. Hummel, M. Steinhoff, C. C. Geilen, H. Orawa, H. Stein, and C. E. Orfanos Early TCR-{beta} and TCR-{gamma} PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications Blood, January 15, 2005; 105(2): 503 - 510. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Fecteau and S. Neron CD40 Stimulation of Human Peripheral B Lymphocytes: Distinct Response from Naive and Memory Cells J. Immunol., November 1, 2003; 171(9): 4621 - 4629. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-H. Weitkamp, N. Kallewaard, K. Kusuhara, E. Bures, J. V. Williams, B. LaFleur, H. B. Greenberg, and J. E. Crowe Jr. Infant and Adult Human B Cell Responses to Rotavirus Share Common Immunodominant Variable Gene Repertoires J. Immunol., November 1, 2003; 171(9): 4680 - 4688. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Wingren, A. B. Edmundson, and C. A.K. Borrebaeck Designing proteins to crystallize through {beta}-strand pairing Protein Eng. Des. Sel., April 1, 2003; 16(4): 255 - 264. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-P. Lefranc IMGT, the international ImMunoGeneTics database(R) Nucleic Acids Res., January 1, 2003; 31(1): 307 - 310. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Pu, J. A. Carrero, and E. R. Unanue Distinct recognition by two subsets of T cells of an MHC class II-peptide complex PNAS, June 25, 2002; 99(13): 8844 - 8849. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Elemento, O. Gascuel, and M.-P. Lefranc Reconstructing the Duplication History of Tandemly Repeated Genes Mol. Biol. Evol., March 1, 2002; 19(3): 278 - 288. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Stoesser, W. Baker, A. van den Broek, E. Camon, M. Garcia-Pastor, C. Kanz, T. Kulikova, R. Leinonen, Q. Lin, V. Lombard, et al. The EMBL Nucleotide Sequence Database Nucleic Acids Res., January 1, 2002; 30(1): 21 - 26. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Daubenberger, M. Salomon, W. Vecino, B. Hubner, H. Troll, R. Rodriques, M. E. Patarroyo, and G. Pluschke Functional and Structural Similarity of V{gamma}9V{delta}2 T Cells in Humans and Aotus Monkeys, a Primate Infection Model for Plasmodium falciparum Malaria J. Immunol., December 1, 2001; 167(11): 6421 - 6430. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Arce, D. G. Jackson, M. A. Gill, L. B. Bennett, J. Banchereau, and V. Pascual Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus J. Immunol., August 15, 2001; 167(4): 2361 - 2369. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Lieby, A. Soley, H. Levallois, B. Hugel, J.-M. Freyssinet, M. Cerutti, J.-L. Pasquali, and T. Martin The clonal analysis of anticardiolipin antibodies in a single patient with primary antiphospholipid syndrome reveals an extreme antibody heterogeneity Blood, June 15, 2001; 97(12): 3820 - 3828. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Stoesser, W. Baker, A. van den Broek, E. Camon, M. Garcia-Pastor, C. Kanz, T. Kulikova, V. Lombard, R. Lopez, H. Parkinson, et al. The EMBL nucleotide sequence database Nucleic Acids Res., January 1, 2001; 29(1): 17 - 21. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-P. Lefranc IMGT, the international ImMunoGeneTics database Nucleic Acids Res., January 1, 2001; 29(1): 207 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Robinson, M. J. Waller, P. Parham, J. G. Bodmer, and S. G. E. Marsh IMGT/HLA Database--a sequence database for the human major histocompatibility complex Nucleic Acids Res., January 1, 2001; 29(1): 210 - 213. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-L. Huret, P. Dessen, and A. Bernheim Atlas of Genetics and Cytogenetics in Oncology and Haematology, updated Nucleic Acids Res., January 1, 2001; 29(1): 303 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Polakova, D. Plaksin, D. H. Chung, I. M. Belyakov, J. A. Berzofsky, and D. H. Margulies Antibodies Directed Against the MHC-I Molecule H-2Dd Complexed with an Antigenic Peptide: Similarities to a T Cell Receptor with the Same Specificity J. Immunol., November 15, 2000; 165(10): 5703 - 5712. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. S. Kohane Bioinformatics and Clinical Informatics: The Imperative to Collaborate J. Am. Med. Inform. Assoc., September 1, 2000; 7(5): 512 - 516. [Full Text]
|
|