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Nucleic Acids Research, 2000, Vol. 28, No. 1 254-256
© 2000 Oxford University Press

The ASTRAL compendium for protein structure and sequence analysis

Steven E. Brenner*, Patrice Koehl and Michael Levitt

Department of Structural Biology, Stanford University, Fairchild Building D-109, Stanford, CA 94305-5126, USA

The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included in the system summarize the overall characteristics of a protein structure. A structural alignments database indicates residue equivalencies in superimposed protein domain structures. The PDB sequence-map files provide a linkage between the amino acid sequence of the molecule studied (SEQRES records in a database entry) and the sequence of the atoms experimentally observed in the structure (ATOM records). These maps are combined with information in the SCOP database to provide sequences of protein domains. Selected subsets of the domain database, with varying degrees of similarity measured in several different ways, are also available. ASTRALmay be accessed at http://astral.stanford.edu/

* To whom correspondence should be addressed at present address: Department of Plant and Microbial Biology, 461A Koshland, University of California, Berkeley, CA 94720-3102, USA. Tel: +1 510 462 9999; Fax: +1 208 279 8978; Email: brenner@compbio.berkeley.edu


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