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Nucleic Acids Research, 2000, Vol. 28, No. 1 289-291
© 2000 Oxford University Press

DIP: the Database of Interacting Proteins

Ioannis Xenarios, Danny W. Rice, Lukasz Salwinski, Marisa K. Baron, Edward M. Marcotte and David Eisenberg*

UCLA-DOE Laboratory of Structural Biology and Molecular Medicine, Molecular Biology Institute, PO Box 951570, UCLA, Los Angeles, CA 90095-1570, USA

The Database of Interacting Proteins (DIP; http://dip.doe-mbi.ucla.edu ) is a database that documents experimentally determined protein–protein interactions. This database is intended to provide the scientific community with a comprehensive and integrated tool for browsing and efficiently extracting information about protein interactions and interaction networks in biological processes. Beyond cataloging details of protein–protein interactions, the DIP is useful for understanding protein function and protein–protein relationships, studying the properties of networks of interacting proteins, benchmarking predictions of protein–protein interactions, and studying the evolution of protein–protein interactions.

* To whom correspondence should be addressed. Tel: +1 310 825 3754; Fax: +1 310 206 3914; Email: david@mbi.ucla.edu


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