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Nucleic Acids Research, 2000, Vol. 28, No. 1 298-301
© 2000 Oxford University Press

Transcription Regulatory Regions Database (TRRD): its status in 2000

N. A. Kolchanov*, O. A. Podkolodnaya, E. A. Ananko, E. V. Ignatieva, I. L. Stepanenko, O. V. Kel-Margoulis, A. E. Kel, T. I. Merkulova, T. N. Goryachkovskaya, T. V. Busygina, F. A. Kolpakov, N. L. Podkolodny, A. N. Naumochkin, I. M. Korostishevskaya, A. G. Romashchenko and G. C. Overton1

Institute of Cytology and Genetics (Siberian Branch of the Russian Academy of Sciences), Lavrentieva 10, Novosibirsk 630090, Russia and 1University of Pennsylvania, Philadelphia, PA, USA

Transcription Regulatory Regions Database (TRRD) has been developed for accumulation of experimental information on the structure–function features of regulatory regions of eukaryotic genes. Each entry in TRRD corresponds to a particular gene and contains a description of structure–function features of its regulatory regions (transcription factor binding sites, promoters, enhancers, silencers, etc.) and gene expression regulation patterns. The current release, TRRD 4.2.5, comprises the description of 760 genes, 3403 expression patterns, and >4600 regulatory elements including 3604 transcription factor binding sites, 600 promoters and 152 enhancers. This information was obtained through annotation of 2537 scientific publications. TRRD 4.2.5 is available through the WWW at http://wwwmgs.bionet.nsc.ru/mgs/dbases/trrd4/

* To whom correspondence should be addressed. Tel: +7 3832 333468; Fax: +7 3832 331278; Email: kol@bionet.nsc.ru


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