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Nucleic Acids Research, 2000, Vol. 28, No. 1 56-59
© 2000 Oxford University Press

The EcoCyc and MetaCyc databases

Peter D. Karp*, Monica Riley1, Milton Saier2, Ian T. Paulsen2, Suzanne M. Paley and Alida Pellegrini-Toole1

SRI International, 333 Ravenswood Avenue, EK223, Menlo Park, CA 94025, USA, 1Marine Biological Laboratory, Woods Hole, MA 02543, USA and 2Department of Biology, University of California at San Diego, La Jolla, CA 92093-0116, USA

EcoCyc is an organism-specific Pathway/Genome Database that describes the metabolic and signal-transduction pathways of Escherichia coli, its enzymes, and—a new addition—its transport proteins. MetaCyc is a new metabolic-pathway database that describes pathways and enzymes of many different organisms, with a microbial focus. Both databases are queried using the Pathway Tools graphical user interface, which provides a wide variety of query operations and visualization tools. EcoCyc and MetaCyc are available at http://ecocyc.PangeaSystems. com/ecocyc/

* To whom correspondence should be addressed. Tel: +1 650 859 4358; Fax: +1 650 859 3735; Email: pkarp@ai.sri.com


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