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Nucleic Acids Research, 2000, Vol. 28, No. 1 68-71
© 2000 Oxford University Press

EMGLib: the Enhanced Microbial Genomes Library (update 2000)

Guy Perrière*, Philippe Bessières1 and Bernard Labedan2

Laboratoire de Biométrie et Biologie Évolutive, Université Claude Bernard, Lyon 1, 43 boulevard du 11 Novembre 1918, 69622 Villeurbanne Cedex, France, 1Laboratoire de Génétique Microbienne, Département de Microbiologie, Institut National de la Recherche en Agronomie, 78350 Jouy-en-Josas, France and 2Institut de Génétique et Microbiologie, Université Paris-Sud, Bâtiment 409, 91405 Orsay Cedex, France

As the number of complete microbial genomes publicly available is still growing, the problem of annotation quality in these very large sequences remains unsolved. Indeed, the number of annotations associated with complete genomes is usually lower than those of the shorter entries encountered in the repository collections. Moreover, classical sequence database management systems have difficulties in handling entries of such size. In this context, the Enhanced Microbial Genomes Library (EMGLib) was developed to try to alleviate these problems. This library contains all the complete genomes from prokaryotes (bacteria and archaea) already sequenced and the yeast genome in GenBank format. The annotations are improved by the introduction of data on codon usage, gene orientation on the chromosome and gene families. It is possible to access EMGLib through two database systems set up on WWW servers: the PBIL server at http://pbil.univ-lyon1.fr/emglib/emglib.html and the MICADO server at http://locus.jouy.inra.fr/micado

* To whom correspondence should be addressed. Tel: +33 4 72 44 62 96; Fax: +33 4 78 89 27 19; Email: perriere@biomserv.univ-lyon1.fr


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