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Nucleic Acids Research, 2001, Vol. 29, No. 1 114-117
© 2001 Oxford University Press

The Medicago Genome Initiative: a model legume database

Callum J. Bell, Richard A. Dixon1, Andrew D. Farmer, Raul Flores, Jeff Inman, Robert A. Gonzales1, Maria J. Harrison1, Nancy L. Paiva1, Angela D. Scott1, Jennifer W. Weller2 and Gregory D. May1,*

The National Center for Genome Resources, 2935 Rodeo Park Drive East, Santa Fe, NM 87505, USA, 1Plant Biology Division, The Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73402, USA and 2Virginia Bioinformatics Institute, 1750 Kraft Drive Suite 1400, Virginia Tech, Blacksburg, VA 24061, USA

The Medicago Genome Initiative (MGI) is a database of EST sequences of the model legume Medicago truncatula. The database is available to the public and has resulted from a collaborative research effort between the Samuel Roberts Noble Foundation and the National Center for Genome Resources to investigate the genome of M.truncatula. MGI is part of the greater integrated Medicago functional genomics program at the Noble Foundation (http://www.noble.org ), which is taking a global approach in studying the genetic and biochemical events associated with the growth, development and environmental interactions of this model legume. Our approach will include: large-scale EST sequencing, gene expression profiling, the generation of M.truncatula activation-tagged and promoter trap insertion mutants, high-throughput metabolic profiling, and proteome studies. These multidisciplinary information pools will be interfaced with one another to provide scientists with an integrated, holistic set of tools to address fundamental questions pertaining to legume biology. The public interface to the MGI database can be accessed at http://www.ncgr.org/research/mgi.

* To whom correspondence should be addressed. Tel. +1 580 221 7391; Fax: +1 580 221 7380; Email: gdmay{at}noble.org


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