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Nucleic Acids Research, 2001, Vol. 29, No. 1 230-233
© 2001 Oxford University Press

NTDB: Thermodynamic Database for Nucleic Acids

Wing Lok Abe Kurtz Chiu, Chun Ngai Sze, Lai Nang Ip, Sze Ki Chan and Steve Chik Fun Au-Yeung*

Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China

A new thermodynamic database for normal and modified nucleic acids has been developed. This Thermodynamic Database for Nucleic Acids (NTDB) includes sequence, structure and thermodynamic information as well as experimental methods and conditions. In this release, there are 1851 sequences containing both normal and modified nucleic acids. A user-friendly web-based interface has been developed to allow data searching under different conditions. Useful thermodynamic tools for the study of nucleic acids have been collected and linked for easy usage. NTDB is available at http://ntdb.chem.cuhk.edu.hk.

* To whom correspondence should be addressed. Tel: +86 852 26096257; Fax: +86 852 26035057; Email: scfau-yeung{at}cuhk.edu.hk


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 Nucleic Acids ResHome page
W. L. A. K. Chiu, C. N. Sze, N. T. Ma, L. F. Chiu, C. W. Leung, and S. C. F. Au-Yeung
NTDB: Thermodynamic Database for Nucleic Acids, Version 2.0
Nucleic Acids Res., January 1, 2003; 31(1): 483 - 485.
[Abstract] [Full Text] [PDF]


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