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Nucleic Acids Research, 2002, Vol. 30, No. 1 369-371
© 2002 Oxford University Press

AngioDB: database of angiogenesis and angiogenesis-related molecules

Tae-Kwon Sohn, Eun-Joung Moon1, Seok-Ki Lee1, Hwan-Gue Cho2 and Kyu-Won Kim3,*

Graduate Program of Bioinformatics, 1Department of Molecular Biology and 2Graphics Application Laboratory, Department of Computer Science, Pusan National University, Pusan 609-735, Korea and 3Angiogenesis Research Laboratory, Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul 151-742, Korea

Angiogenesis is the formation of new capillaries sprouting from pre-existing vessels. Angiogenesis occurs in a variety of normal physiological and pathological conditions and is regulated by a balance of stimulatory and inhibitory angiogenic factors. The control of this balance may fail and result in the formation of a pathologic capillary network during the development of many diseases. Therefore, we developed the angiogenesis database (AngioDB), which can provide a signaling network of angiogenesis-related biomolecules in human. Each record of AngioDB consisted of 12 fields and was developed by using a relational database management system. For the retrieval of data, Active Server Page (ASP) technology was integrated in this system. Users can access the database by a query or imagemap browsing program. The retrieving system also provides a list of angiogenesis-related molecules classified by three categories, and the database has an external link to NCBI databases. AngioDB is available via the Internet at http://angiodb.snu.ac.kr/.

* To whom correspondence should be addressed. Tel: +82 2 880 6988; Fax: +82 2 872 1795; Email: qwonkim{at}plaza.snu.ac.kr


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