Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow Print PDF (173K) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (53)
Right arrowRequest Permissions
Citing Articles
Right arrowScopus Links
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Ng, S.-K.
Right arrow Articles by Lin, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ng, S.-K.
Right arrow Articles by Lin, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 2003, Vol. 31, No. 1 251-254
© 2003 Oxford University Press

InterDom: a database of putative interacting protein domains for validating predicted protein interactions and complexes

See-Kiong Ng*, Zhuo Zhang, Soon-Heng Tan and Kui Lin1

Biocomputing Group, Laboratories for Information Technology, 21 Heng Mui Keng Terrace, 119613 Singapore 1 Genome Institute of Singapore, 1 Science Park Road, #05-01, 117528 Singapore

*To whom correspondence should be addressed. Tel: +65 68746596; Fax: +65 67748056; Email: skng{at}lit.a-star.edu.sg

ABSTRACT

Advances in proteomics technology have enabled new proteins to be discovered at an unprecedented speed, and high throughput experimental methods have been developed to detect protein interactions and complexes en masse. Such bottom-up, data-driven approach has resulted in data that may be uninformative or potentially errorful, requiring further validation and annotation. The InterDom database focuses on providing supporting evidence for the detected protein interactions based on putative protein domain interactions. Using an integrative approach, InterDom derives potential domain interactions by combining data from multiple sources, ranging from domain fusions, protein interactions and complexes, to scientific literature. The InterDom database is available at http://InterDom.lit.org.sg.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 BioinformaticsHome page
C.-C. Wu, S. Asgharzadeh, T. J. Triche, and D. Z. D'Argenio
Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning
Bioinformatics, March 15, 2010; 26(6): 807 - 813.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
S.-E. Schelhorn, T. Lengauer, and M. Albrecht
An integrative approach for predicting interactions of protein regions
Bioinformatics, August 15, 2008; 24(16): i35 - i41.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
J. Pandey, M. Koyuturk, S. Subramaniam, and A. Grama
Functional coherence in domain interaction networks
Bioinformatics, August 15, 2008; 24(16): i28 - i34.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
D. Li, W. Liu, Z. Liu, J. Wang, Q. Liu, Y. Zhu, and F. He
PRINCESS, a Protein Interaction Confidence Evaluation System with Multiple Data Sources
Mol. Cell. Proteomics, June 1, 2008; 7(6): 1043 - 1052.
[Abstract] [Full Text] [PDF]

Home page
 DNA ResHome page
Y. Shimoda, S. Shinpo, M. Kohara, Y. Nakamura, S. Tabata, and S. Sato
A Large Scale Analysis of Protein-Protein Interactions in the Nitrogen-fixing Bacterium Mesorhizobium loti
DNA Res, February 1, 2008; 15(1): 13 - 23.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
B. Raghavachari, A. Tasneem, T. M. Przytycka, and R. Jothi
DOMINE: a database of protein domain interactions
Nucleic Acids Res., January 11, 2008; 36(suppl_1): D656 - D661.
[Abstract] [Full Text] [PDF]

Home page
 DNA ResHome page
S. Sato, Y. Shimoda, A. Muraki, M. Kohara, Y. Nakamura, and S. Tabata
A Large-scale Protein protein Interaction Analysis in Synechocystis sp. PCC6803
DNA Res, November 13, 2007; (2007) dsm021v1.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
A. Schlicker, C. Huthmacher, F. Ramirez, T. Lengauer, and M. Albrecht
Functional evaluation of domain domain interactions and human protein interaction networks
Bioinformatics, April 1, 2007; 23(7): 859 - 865.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. Ceol, A. Chatr-aryamontri, E. Santonico, R. Sacco, L. Castagnoli, and G. Cesareni
DOMINO: a database of domain-peptide interactions
Nucleic Acids Res., January 12, 2007; 35(suppl_1): D557 - D560.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J.-H. Hung, H.-D. Huang, and T.-Y. Lee
ProKware: integrated software for presenting protein structural properties in protein tertiary structures.
Nucleic Acids Res., July 1, 2006; 34(Web Server issue): W89 - W94.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
X.-W. Chen and M. Liu
Prediction of protein-protein interactions using random decision forest framework
Bioinformatics, December 15, 2005; 21(24): 4394 - 4400.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
D. Hwang, J. J. Smith, D. M. Leslie, A. D. Weston, A. G. Rust, S. Ramsey, P. de Atauri, A. F. Siegel, H. Bolouri, J. D. Aitchison, et al.
A data integration methodology for systems biology: Experimental verification
PNAS, November 29, 2005; 102(48): 17302 - 17307.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
K. Okada, S. Kanaya, and K. Asai
Accurate extraction of functional associations between proteins based on common interaction partners and common domains
Bioinformatics, May 1, 2005; 21(9): 2043 - 2048.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
D.-S. Han, H.-S. Kim, W.-H. Jang, S.-D. Lee, and J.-K. Suh
PreSPI: a domain combination based prediction system for protein-protein interaction
Nucleic Acids Res., December 1, 2004; 32(21): 6312 - 6320.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
Z. Zhang and S.-K. Ng
InterWeaver: interaction reports for discovering potential protein interaction partners with online evidence
Nucleic Acids Res., July 1, 2004; 32(suppl_2): W73 - W75.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
A.-C. Tien, M.-H. Lin, L.-J. Su, Y.-R. Hong, T.-S. Cheng, Y.-C. G. Lee, W.-J. Lin, I. H. Still, and C.-Y. F. Huang
Identification of the Substrates and Interaction Proteins of Aurora Kinases from a Protein-Protein Interaction Model
Mol. Cell. Proteomics, January 1, 2004; 3(1): 93 - 104.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.