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Nucleic Acids Research, 2003, Vol. 31, No. 1 294-297
© 2003 Oxford University Press

GPCRDB information system for G protein-coupled receptors

Florence Horn, Emmanuel Bettler1, Laerte Oliveira2, Fabien Campagne3, Fred E. Cohen and Gerrit Vriend*,1

Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA 1 CMBI, University of Nijmegen, The Netherlands 2 Department of Biophysics, EPM, Sao Paulo, Brazil 3 Institute for Computational Biomedicine, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, USA

*To whom correspondence should be addressed. Email: vriend{at}cmbi.kun.nl

ABSTRACT

The GPCRDB is a molecular class-specific information system that collects, combines, validates and disseminates heterogeneous data on G protein-coupled receptors (GPCRs). The database stores data on sequences, ligand binding constants and mutations. The system also provides computationally derived data such as sequence alignments, homology models, and a series of query and visualization tools. The GPCRDB is updated automatically once every 4–5 months and is freely accessible at http://www.gpcr.org/7tm/.


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