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Nucleic Acids Research, 2003, Vol. 31, No. 1 331-333
© 2003 Oxford University Press

NRMD: Nuclear Receptor Mutation Database

Joost J. J. van Durme, Emmanuel Bettler, Simon Folkertsma, Florence Horn1 and Gert Vriend*

CMBI, University of Nijmegen, Nijmegen, The Netherlands 1 Department of Cellular and Molecular Pharmacology, UCSF, Box 0450, San Francisco, CA 94143-0450, USA

*To whom correspondence should be addressed. Email: vriend{at}cmbi.kun.nl

ABSTRACT

The NRMD is a database for nuclear receptor mutation information. It includes mutation information from SWISS-PROT/TrEMBL, several web-based mutation data resources, and data extracted from the literature in a fully automatic manner. Because it is also possible to add mutations manually, a hundred mutations were added for completeness. At present, the NRMD contains information about 893 mutations in 54 nuclear receptors. A common numbering scheme for all nuclear receptors eases the use of the information for many kinds of studies. The NRMD is freely available to academia and industry as a stand-alone version at: www.receptors.org/NR/.


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