Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow Print PDF (321K) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (105)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Pruitt, K. D.
Right arrow Articles by Maglott, D. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pruitt, K. D.
Right arrow Articles by Maglott, D. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 2003, Vol. 31, No. 1 34-37
© 2003 Oxford University Press

NCBI Reference Sequence Project: update and current status

Kim D. Pruitt*, Tatiana Tatusova and Donna R. Maglott

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A Room 6N605, 8600 Rockville Pike, Bethesda, MD 20894, USA

*To whom correspondence should be addressed. Email: pruitt{at}ncbi.nlm.nih.gov

ABSTRACT

The goal of the NCBI Reference Sequence (RefSeq) project is to provide the single best non-redundant and comprehensive collection of naturally occurring biological molecules, representing the central dogma. Nucleotide and protein sequences are explicitly linked on a residue-by-residue basis in this collection. Ideally all molecule types will be available for each well-studied organism, but the initial database collection pragmatically includes only those molecules and organisms that are most readily identified. Thus different amounts of information are available for different organisms at any given time. Furthermore, for some organisms additional intermediate records are provided when the genome sequence is not yet finished. The collection is supplied by NCBI through three distinct pipelines in addition to collaborations with community groups. The collection is curated on an ongoing basis. Additional information about the NCBI RefSeq project is available at http://www.ncbi.nih.gov/RefSeq/.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Neuro OncologyHome page
H. Colman, L. Zhang, E. P. Sulman, J. M. McDonald, N. L. Shooshtari, A. Rivera, S. Popoff, C. L. Nutt, D. N. Louis, J. G. Cairncross, et al.
A multigene predictor of outcome in glioblastoma
Neuro Oncology, October 20, 2009; (2009) nop007v1.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. M. Becker, R. L. Graham, E. F. Donaldson, B. Rockx, A. C. Sims, T. Sheahan, R. J. Pickles, D. Corti, R. E. Johnston, R. S. Baric, et al.
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
PNAS, December 16, 2008; 105(50): 19944 - 19949.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
J. Zhang, Y. Ji, and L. Zhang
Extracting three-way gene interactions from microarray data
Bioinformatics, November 1, 2007; 23(21): 2903 - 2909.
[Abstract] [Full Text] [PDF]

Home page
 DNA ResHome page
D. Gherbassi, L. Bhatt, S. Thuret, and H. H. Simon
Merging Mouse Transcriptome Analyses with Parkinson's Disease Linkage Studies
DNA Res, May 23, 2007; (2007) dsm007v1.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
B. J. Frey and D. Dueck
Clustering by Passing Messages Between Data Points
Science, February 16, 2007; 315(5814): 972 - 976.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. G. Jegga, J. Chen, S. Gowrisankar, M. A. Deshmukh, R. Gudivada, S. Kong, V. Kaimal, and B. J. Aronow
GenomeTrafac: a whole genome resource for the detection of transcription factor binding site clusters associated with conventional and microRNA encoding genes conserved between mouse and human gene orthologs
Nucleic Acids Res., January 12, 2007; 35(suppl_1): D116 - D121.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
M. Semon and L. Duret
Evolutionary Origin and Maintenance of Coexpressed Gene Clusters in Mammals
Mol. Biol. Evol., September 1, 2006; 23(9): 1715 - 1723.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. S. Siddiqui, A. D. Delaney, A. Schnerch, O. L. Griffith, S. J. M. Jones, and M. A. Marra
Sequence biases in large scale gene expression profiling data
Nucleic Acids Res., July 13, 2006; 34(12): e83 - e83.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
S. Yamazaki, J. Yamazaki, K. Nishijima, R. Otsuka, M. Mise, H. Ishikawa, K. Sasaki, S.-i. Tago, and K. Isono
Proteome Analysis of an Aerobic Hyperthermophilic Crenarchaeon, Aeropyrum pernix K1
Mol. Cell. Proteomics, May 1, 2006; 5(5): 811 - 823.
[Abstract] [Full Text] [PDF]

Home page
 Brief BioinformHome page
L. Florea
Bioinformatics of alternative splicing and its regulation
Brief Bioinform, March 1, 2006; 7(1): 55 - 69.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
L. Cui, N. Veeraraghavan, A. Richter, K. Wall, R. K. Jansen, J. Leebens-Mack, I. Makalowska, and C. W. dePamphilis
ChloroplastDB: the Chloroplast Genome Database
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D692 - D696.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. S. Siddiqui, J. Khattra, A. D. Delaney, Y. Zhao, C. Astell, J. Asano, R. Babakaiff, S. Barber, J. Beland, S. Bohacec, et al.
A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells
PNAS, December 20, 2005; 102(51): 18485 - 18490.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Maiorino, A. Roveri, L. Benazzi, V. Bosello, P. Mauri, S. Toppo, S. C. E. Tosatto, and F. Ursini
Functional Interaction of Phospholipid Hydroperoxide Glutathione Peroxidase with Sperm Mitochondrion-associated Cysteine-rich Protein Discloses the Adjacent Cysteine Motif as a New Substrate of the Selenoperoxidase
J. Biol. Chem., November 18, 2005; 280(46): 38395 - 38402.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
N. Osada, M. Hirata, R. Tanuma, J. Kusuda, M. Hida, Y. Suzuki, S. Sugano, T. Gojobori, C.-K. J. Shen, C.-I Wu, et al.
Substitution Rate and Structural Divergence of 5'UTR Evolution: Comparative Analysis Between Human and Cynomolgus Monkey cDNAs
Mol. Biol. Evol., October 1, 2005; 22(10): 1976 - 1982.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
A. Siepel, G. Bejerano, J. S. Pedersen, A. S. Hinrichs, M. Hou, K. Rosenbloom, H. Clawson, J. Spieth, L. W. Hillier, S. Richards, et al.
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
Genome Res., August 1, 2005; 15(8): 1034 - 1050.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
T. H. Kim, L. O. Barrera, C. Qu, S. Van Calcar, N. D. Trinklein, S. J. Cooper, R. M. Luna, C. K. Glass, M. G. Rosenfeld, R. M. Myers, et al.
Direct isolation and identification of promoters in the human genome
Genome Res., June 1, 2005; 15(6): 830 - 839.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
T.-H. Kim, Y.-J. Jeon, W.-Y. Kim, and H.-S. Kim
HESAS: HERVs Expression and Structure Analysis System
Bioinformatics, April 15, 2005; 21(8): 1699 - 1700.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Virol.Home page
F. Ferron, C. Rancurel, S. Longhi, C. Cambillau, B. Henrissat, and B. Canard
VaZyMolO: a tool to define and classify modularity in viral proteins
J. Gen. Virol., March 1, 2005; 86(3): 743 - 749.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. Harbig, R. Sprinkle, and S. A. Enkemann
A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array
Nucleic Acids Res., February 18, 2005; 33(3): e31 - e31.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
C. B. Do, M. S.P. Mahabhashyam, M. Brudno, and S. Batzoglou
ProbCons: Probabilistic consistency-based multiple sequence alignment
Genome Res., February 1, 2005; 15(2): 330 - 340.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
M. Semon, D. Mouchiroud, and L. Duret
Relationship between gene expression and GC-content in mammals: statistical significance and biological relevance
Hum. Mol. Genet., February 1, 2005; 14(3): 421 - 427.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. E. Vinogradov
Noncoding DNA, isochores and gene expression: nucleosome formation potential
Nucleic Acids Res., January 26, 2005; 33(2): 559 - 563.
[Abstract] [Full Text] [PDF]

Home page
 RNAHome page
C. ZWIEB, R. W. VAN NUES, M. A. ROSENBLAD, J. D. BROWN, and T. SAMUELSSON
A nomenclature for all signal recognition particle RNAs
RNA, January 1, 2005; 11(1): 7 - 13.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
T. P. V. Manh, M. Mokrane, E. Georgenthum, J. Flavigny, L. Carrier, M. Semeriva, M. Piovant, and L. Roder
Expression of cardiac myosin-binding protein-C (cMyBP-C) in Drosophila as a model for the study of human cardiomyopathies
Hum. Mol. Genet., January 1, 2005; 14(1): 7 - 17.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
E. Barta, E. Sebestyen, T. B. Palfy, G. Toth, C. P. Ortutay, and L. Patthy
DoOP: Databases of Orthologous Promoters, collections of clusters of orthologous upstream sequences from chordates and plants
Nucleic Acids Res., January 1, 2005; 33(suppl_1): D86 - D90.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
J. F. Abril, R. Castelo, and R. Guigo
Comparison of splice sites in mammals and chicken
Genome Res., January 1, 2005; 15(1): 111 - 119.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. M. Chalk, R. E. Warfinge, P. Georgii-Hemming, and E. L. L. Sonnhammer
siRNAdb: a database of siRNA sequences
Nucleic Acids Res., January 1, 2005; 33(suppl_1): D131 - D134.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
F. Mignone, G. Grillo, F. Licciulli, M. Iacono, S. Liuni, P. J. Kersey, J. Duarte, C. Saccone, and G. Pesole
UTRdb and UTRsite: a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs
Nucleic Acids Res., January 1, 2005; 33(suppl_1): D141 - D146.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
P. Kersey, L. Bower, L. Morris, A. Horne, R. Petryszak, C. Kanz, A. Kanapin, U. Das, K. Michoud, I. Phan, et al.
Integr8 and Genome Reviews: integrated views of complete genomes and proteomes
Nucleic Acids Res., January 1, 2005; 33(suppl_1): D297 - D302.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
T. Hubbard, D. Andrews, M. Caccamo, G. Cameron, Y. Chen, M. Clamp, L. Clarke, G. Coates, T. Cox, F. Cunningham, et al.
Ensembl 2005
Nucleic Acids Res., January 1, 2005; 33(suppl_1): D447 - D453.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
The ENCODE Project Consortium
The ENCODE (ENCyclopedia Of DNA Elements) Project
Science, October 22, 2004; 306(5696): 636 - 640.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
T. S. Furey, M. Diekhans, Y. Lu, T. A. Graves, L. Oddy, J. Randall-Maher, L. W. Hillier, R. K. Wilson, and D. Haussler
Analysis of Human mRNAs With the Reference Genome Sequence Reveals Potential Errors, Polymorphisms, and RNA Editing
Genome Res., October 1, 2004; 14(10b): 2034 - 2040.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
The MGC Project Team
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res., October 1, 2004; 14(10b): 2121 - 2127.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
P. N. Robinson, U. Bohme, R. Lopez, S. Mundlos, and P. Nurnberg
Gene-Ontology analysis reveals association of tissue-specific 5' CpG-island genes with development and embryogenesis
Hum. Mol. Genet., September 1, 2004; 13(17): 1969 - 1978.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. GenomicsHome page
B. H. Mecham, D. Z. Wetmore, Z. Szallasi, Y. Sadovsky, I. Kohane, and T. J. Mariani
Increased measurement accuracy for sequence-verified microarray probes
Physiol Genomics, August 11, 2004; 18(3): 308 - 315.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
Y. Bao, S. Federhen, D. Leipe, V. Pham, S. Resenchuk, M. Rozanov, R. Tatusov, and T. Tatusova
National Center for Biotechnology Information Viral Genomes Project
J. Virol., July 15, 2004; 78(14): 7291 - 7298.
[Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
N. Kim, S. Shin, and S. Lee
ASmodeler: gene modeling of alternative splicing from genomic alignment of mRNA, EST and protein sequences
Nucleic Acids Res., July 1, 2004; 32(suppl_2): W181 - W186.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
Y. Han, K. Lassen, D. Monie, A. R. Sedaghat, S. Shimoji, X. Liu, T. C. Pierson, J. B. Margolick, R. F. Siliciano, and J. D. Siliciano
Resting CD4+ T Cells from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals Carry Integrated HIV-1 Genomes within Actively Transcribed Host Genes
J. Virol., June 15, 2004; 78(12): 6122 - 6133.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
M. Kiriakidou, P. T. Nelson, A. Kouranov, P. Fitziev, C. Bouyioukos, Z. Mourelatos, and A. Hatzigeorgiou
A combined computational-experimental approach predicts human microRNA targets
Genes & Dev., May 15, 2004; 18(10): 1165 - 1178.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
R. C. Edgar
MUSCLE: multiple sequence alignment with high accuracy and high throughput
Nucleic Acids Res., March 19, 2004; 32(5): 1792 - 1797.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
E. W. Klee, D. F. Carlson, S. C. Fahrenkrug, S. C. Ekker, and L. B. M. Ellis
Identifying secretomes in people, pufferfish and pigs
Nucleic Acids Res., February 27, 2004; 32(4): 1414 - 1421.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
D. L. Wheeler, D. M. Church, R. Edgar, S. Federhen, W. Helmberg, T. L. Madden, J. U. Pontius, G. D. Schuler, L. M. Schriml, E. Sequeira, et al.
Database resources of the National Center for Biotechnology Information: update
Nucleic Acids Res., January 1, 2004; 32(90001): D35 - 40.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
C. D. Schmid, V. Praz, M. Delorenzi, R. Perier, and P. Bucher
The Eukaryotic Promoter Database EPD: the impact of in silico primer extension
Nucleic Acids Res., January 1, 2004; 32(90001): D82 - 85.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
P. Divina and J. Forejt
The Mouse SAGE Site: database of public mouse SAGE libraries
Nucleic Acids Res., January 1, 2004; 32(90001): D482 - 483.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
K. Akagi, T. Suzuki, R. M. Stephens, N. A. Jenkins, and N. G. Copeland
RTCGD: retroviral tagged cancer gene database
Nucleic Acids Res., January 1, 2004; 32(90001): D523 - 527.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
T. Ruggiero, M. Olivero, A. Follenzi, L. Naldini, R. Calogero, and M. F. Di Renzo
Deletion in a (T)8 microsatellite abrogates expression regulation by 3'-UTR
Nucleic Acids Res., November 15, 2003; 31(22): 6561 - 6569.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. K. Chanda, S. White, A. P. Orth, R. Reisdorph, L. Miraglia, R. S. Thomas, P. DeJesus, D. E. Mason, Q. Huang, R. Vega, et al.
From the Cover: Genome-scale functional profiling of the mammalian AP-1 signaling pathway
PNAS, October 14, 2003; 100(21): 12153 - 12158.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
W. J. Kent, R. Baertsch, A. Hinrichs, W. Miller, and D. Haussler
Evolution's cauldron: Duplication, deletion, and rearrangement in the mouse and human genomes
PNAS, September 30, 2003; 100(20): 11484 - 11489.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. S. Halees, D. Leyfer, and Z. Weng
PromoSer: a large-scale mammalian promoter and transcription start site identification service
Nucleic Acids Res., July 1, 2003; 31(13): 3554 - 3559.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
D. L. Wheeler, D. M. Church, S. Federhen, A. E. Lash, T. L. Madden, J. U. Pontius, G. D. Schuler, L. M. Schriml, E. Sequeira, T. A. Tatusova, et al.
Database resources of the National Center for Biotechnology
Nucleic Acids Res., January 1, 2003; 31(1): 28 - 33.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.