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Nucleic Acids Research, 2003, Vol. 31, No. 13 3471-3476
© 2003 Oxford University Press

GenePublisher: automated analysis of DNA microarray data

Steen Knudsen*,1, Christopher Workman1, Thomas Sicheritz-Ponten1,2 and Carsten Friis1

1 Center for Biological Sequence Analysis, BioCentrum-DTU, 2800 Lyngby, Denmark 2 Department of Medicinal Chemistry, Division of Pharmacognosy, Uppsala University, Sweden

*To whom correspondence should be addressed. Tel: +45 45 25 24 80; Fax: +45 45 93 15 85; Email: steen{at}cbs.dtu.dk

GenePublisher, a system for automatic analysis of data from DNA microarray experiments, has been implemented with a web interface at http://www.cbs.dtu.dk/services/GenePublisher. Raw data are uploaded to the server together with a specification of the data. The server performs normalization, statistical analysis and visualization of the data. The results are run against databases of signal transduction pathways, metabolic pathways and promoter sequences in order to extract more information. The results of the entire analysis are summarized in report form and returned to the user.


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