Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow Print PDF (517K) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (287)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Obenauer, J. C.
Right arrow Articles by Yaffe, M. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Obenauer, J. C.
Right arrow Articles by Yaffe, M. B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 2003, Vol. 31, No. 13 3635-3641
© 2003 Oxford University Press

Scansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifs

John C. Obenauer, Lewis C. Cantley1 and Michael B. Yaffe*

Center for Cancer Research, E18-580, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA 1 Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA, USA

*To whom correspondence should be addressed. Tel: +1 6174522103; Fax: +1 6174524978; Email: myaffe{at}mit.edu

Scansite identifies short protein sequence motifs that are recognized by modular signaling domains, phosphorylated by protein Ser/Thr- or Tyr-kinases or mediate specific interactions with protein or phospholipid ligands. Each sequence motif is represented as a position-specific scoring matrix (PSSM) based on results from oriented peptide library and phage display experiments. Predicted domain-motif interactions from Scansite can be sequentially combined, allowing segments of biological pathways to be constructed in silico. The current release of Scansite, version 2.0, includes 62 motifs characterizing the binding and/or substrate specificities of many families of Ser/Thr- or Tyr-kinases, SH2, SH3, PDZ, 14-3-3 and PTB domains, together with signature motifs for PtdIns(3,4,5)P3-specific PH domains. Scansite 2.0 contains significant improvements to its original interface, including a number of new generalized user features and significantly enhanced performance. Searches of all SWISS-PROT, TrEMBL, Genpept and Ensembl protein database entries are now possible with run times reduced by ~60% when compared with Scansite version 1.0. Scansite 2.0 allows restricted searching of species-specific proteins, as well as isoelectric point and molecular weight sorting to facilitate comparison of predictions with results from two-dimensional gel electrophoresis experiments. Support for user-defined motifs has been increased, allowing easier input of user-defined matrices and permitting user-defined motifs to be combined with pre-compiled Scansite motifs for dual motif searching. In addition, a new series of Sequence Match programs for non-quantitative user-defined motifs has been implemented. Scansite is available via the World Wide Web at http://scansite.mit.edu.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Mol. Biol. CellHome page
R. Sarker, M. Gronborg, B. Cha, S. Mohan, Y. Chen, A. Pandey, D. Litchfield, M. Donowitz, and X. Li
Casein Kinase 2 Binds to the C Terminus of Na+/H+ exchanger 3 (NHE3) and Stimulates NHE3 Basal Activity by Phosphorylating a Separate Site in NHE3
Mol. Biol. Cell, September 1, 2008; 19(9): 3859 - 3870.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
C.-Y. Yang, C.-H. Chang, Y.-L. Yu, T.-C. E. Lin, S.-A. Lee, C.-C. Yen, J.-M. Yang, J.-M. Lai, Y.-R. Hong, T.-L. Tseng, et al.
PhosphoPOINT: a comprehensive human kinase interactome and phospho-protein database
Bioinformatics, August 15, 2008; 24(16): i14 - i20.
[Abstract] [PDF]

Home page
 BioinformaticsHome page
P. Radivojac, P. H. Baenziger, M. G. Kann, M. E. Mort, M. W. Hahn, and S. D. Mooney
Gain and loss of phosphorylation sites in human cancer
Bioinformatics, August 15, 2008; 24(16): i241 - i247.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
S. Granum, T. C. B. Andersen, M. Sorlie, M. Jorgensen, L. Koll, T. Berge, T. Lea, B. Fleckenstein, A. Spurkland, and V. Sundvold-Gjerstad
Modulation of Lck Function through Multisite Docking to T Cell-specific Adapter Protein
J. Biol. Chem., August 8, 2008; 283(32): 21909 - 21919.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
A. J. Snow, P. Puri, A. Acker-Palmer, T. Bouwmeester, S. Vijayaraghavan, and D. Kline
Phosphorylation-Dependent Interaction of Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein (YWHA) with PADI6 Following Oocyte Maturation in Mice
Biol Reprod, August 1, 2008; 79(2): 337 - 347.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
W. Jiang, M. Betson, R. Mulloy, R. Foster, M. Levay, E. Ligeti, and J. Settleman
p190A RhoGAP Is a Glycogen Synthase Kinase-3-{beta} Substrate Required for Polarized Cell Migration
J. Biol. Chem., July 25, 2008; 283(30): 20978 - 20988.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
M. O. Collins, L. Yu, I. Campuzano, S. G. N. Grant, and J. S. Choudhary
Phosphoproteomic Analysis of the Mouse Brain Cytosol Reveals a Predominance of Protein Phosphorylation in Regions of Intrinsic Sequence Disorder
Mol. Cell. Proteomics, July 1, 2008; 7(7): 1331 - 1348.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
K. Sakamoto and G. D. Holman
Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
Am J Physiol Endocrinol Metab, July 1, 2008; 295(1): E29 - E37.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
N. F. W. Saunders and B. Kobe
The Predikin webserver: improved prediction of protein kinase peptide specificity using structural information
Nucleic Acids Res., July 1, 2008; 36(suppl_2): W286 - W290.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Pham, M. B. Smolka, P. Calabrese, A. Landolph, K. Zhang, H. Zhou, and M. F. Goodman
Impact of Phosphorylation and Phosphorylation-null Mutants on the Activity and Deamination Specificity of Activation-induced Cytidine Deaminase
J. Biol. Chem., June 20, 2008; 283(25): 17428 - 17439.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
L. Li, C. Wu, H. Huang, K. Zhang, J. Gan, and S. S.-C. Li
Prediction of phosphotyrosine signaling networks using a scoring matrix-assisted ligand identification approach
Nucleic Acids Res., June 1, 2008; 36(10): 3263 - 3273.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
V. Lopez-Pajares, M. M. Kim, and Z.-M. Yuan
Phosphorylation of MDMX Mediated by Akt Leads to Stabilization and Induces 14-3-3 Binding
J. Biol. Chem., May 16, 2008; 283(20): 13707 - 13713.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Q. Tong, I. Hirschler-Laszkiewicz, W. Zhang, K. Conrad, D. W. Neagley, D. L. Barber, J. Y. Cheung, and B. A. Miller
TRPC3 Is the Erythropoietin-regulated Calcium Channel in Human Erythroid Cells
J. Biol. Chem., April 18, 2008; 283(16): 10385 - 10395.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
R. S Thomas, N. Sarwar, F. Phoenix, R C. Coombes, and S. Ali
Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-{alpha} activity
J. Mol. Endocrinol., April 1, 2008; 40(4): 173 - 184.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. Guo, X. Wu, D.-Y. Zhang, and K. Lin
Genome-wide inference of protein interaction sites: lessons from the yeast high-quality negative protein-protein interaction dataset
Nucleic Acids Res., April 1, 2008; 36(6): 2002 - 2011.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
H. Huang, L. Li, C. Wu, D. Schibli, K. Colwill, S. Ma, C. Li, P. Roy, K. Ho, Z. Songyang, et al.
Defining the Specificity Space of the Human Src Homology 2 Domain
Mol. Cell. Proteomics, April 1, 2008; 7(4): 768 - 784.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P.-H. Yang, W. K. C. Cheung, Y. Peng, M.-L. He, G.-Q. Wu, D. Xie, B.-H. Jiang, Q.-H. Huang, Z. Chen, M. C. M. Lin, et al.
Makorin-2 Is a Neurogenesis Inhibitor Downstream of Phosphatidylinositol 3-Kinase/Akt (PI3K/Akt) Signal
J. Biol. Chem., March 28, 2008; 283(13): 8486 - 8495.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. Wan, S. Kang, C. Tang, J. Yan, Y. Ren, J. Liu, X. Gao, A. Banerjee, L. B. M. Ellis, and T. Li
Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection
Nucleic Acids Res., March 27, 2008; 36(4): e22 - e22.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. D. Blethrow, J. S. Glavy, D. O. Morgan, and K. M. Shokat
Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates
PNAS, February 5, 2008; 105(5): 1442 - 1447.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
G. Paroni, N. Cernotta, C. Dello Russo, P. Gallinari, M. Pallaoro, C. Foti, F. Talamo, L. Orsatti, C. Steinkuhler, and C. Brancolini
PP2A Regulates HDAC4 Nuclear Import
Mol. Biol. Cell, February 1, 2008; 19(2): 655 - 667.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Hoffmeister, P. Riha, O. Neumuller, O. Danielewski, J. Schultess, and A. P. Smolenski
Cyclic Nucleotide-dependent Protein Kinases Inhibit Binding of 14-3-3 to the GTPase-activating Protein Rap1GAP2 in Platelets
J. Biol. Chem., January 25, 2008; 283(4): 2297 - 2306.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
J. M. Gonzalez-Santos, H. Cao, R. C. Duan, and J. Hu
Mutation in the splicing factor Hprp3p linked to retinitis pigmentosa impairs interactions within the U4/U6 snRNP complex
Hum. Mol. Genet., January 15, 2008; 17(2): 225 - 239.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
R. Linding, L. J. Jensen, A. Pasculescu, M. Olhovsky, K. Colwill, P. Bork, M. B. Yaffe, and T. Pawson
NetworKIN: a resource for exploring cellular phosphorylation networks
Nucleic Acids Res., January 11, 2008; 36(suppl_1): D695 - D699.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
W. Gong, D. Zhou, Y. Ren, Y. Wang, Z. Zuo, Y. Shen, F. Xiao, Q. Zhu, A. Hong, X. Zhou, et al.
PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains
Nucleic Acids Res., January 11, 2008; 36(suppl_1): D679 - D683.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
H. Dinkel and H. Sticht
A computational strategy for the prediction of functional linear peptide motifs in proteins
Bioinformatics, December 15, 2007; 23(24): 3297 - 3303.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. P. Stokes, J. Rush, J. MacNeill, J. M. Ren, K. Sprott, J. Nardone, V. Yang, S. A. Beausoleil, S. P. Gygi, M. Livingstone, et al.
Profiling of UV-induced ATM/ATR signaling pathways
PNAS, December 11, 2007; 104(50): 19855 - 19860.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. W. Anantha, V. M. Vassin, and J. A. Borowiec
Sequential and Synergistic Modification of Human RPA Stimulates Chromosomal DNA Repair
J. Biol. Chem., December 7, 2007; 282(49): 35910 - 35923.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J.-S. Kim, B. A. Diebold, B. M. Babior, U. G. Knaus, and G. M. Bokoch
Regulation of Nox1 Activity via Protein Kinase A-mediated Phosphorylation of NoxA1 and 14-3-3 Binding
J. Biol. Chem., November 30, 2007; 282(48): 34787 - 34800.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. Y. Delgado, M. Coba, C. N. G. Anderson, K. R. Thompson, E. E. Gray, C. L. Heusner, K. C. Martin, S. G. N. Grant, and T. J. O'Dell
NMDA Receptor Activation Dephosphorylates AMPA Receptor Glutamate Receptor 1 Subunits at Threonine 840
J. Neurosci., November 28, 2007; 27(48): 13210 - 13221.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
M. W. Mayhew, E. D. Jeffery, N. E. Sherman, K. Nelson, J. M. Polefrone, S. J. Pratt, J. Shabanowitz, J. T. Parsons, J. W. Fox, D. F. Hunt, et al.
Identification of phosphorylation sites in betaPIX and PAK1
J. Cell Sci., November 15, 2007; 120(22): 3911 - 3918.
[Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Zhang, V. Brovkovych, S. Brovkovych, F. Tan, B.-S. Lee, T. Sharma, and R. A. Skidgel
Dynamic Receptor-dependent Activation of Inducible Nitric-oxide Synthase by ERK-mediated Phosphorylation of Ser745
J. Biol. Chem., November 2, 2007; 282(44): 32453 - 32461.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
J. E. Hutti, B. E. Turk, J. M. Asara, A. Ma, L. C. Cantley, and D. W. Abbott
I{kappa}B Kinase {beta} Phosphorylates the K63 Deubiquitinase A20 To Cause Feedback Inhibition of the NF-{kappa}B Pathway
Mol. Cell. Biol., November 1, 2007; 27(21): 7451 - 7461.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
C. Medina-Palazon, H. Gruffat, F. Mure, O. Filhol, V. Vingtdeux-Didier, H. Drobecq, C. Cochet, N. Sergeant, A. Sergeant, and E. Manet
Protein Kinase CK2 Phosphorylation of EB2 Regulates Its Function in the Production of Epstein-Barr Virus Infectious Viral Particles
J. Virol., November 1, 2007; 81(21): 11850 - 11860.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
L. Cao, K. Yu, C. Banh, V. Nguyen, A. Ritz, B. J. Raphael, Y. Kawakami, T. Kawakami, and A. R. Salomon
Quantitative Time-Resolved Phosphoproteomic Analysis of Mast Cell Signaling
J. Immunol., November 1, 2007; 179(9): 5864 - 5876.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
E. Com, C. Lagadec, A. Page, I. El Yazidi-Belkoura, C. Slomianny, A. Spencer, D. Hammache, B. B. Rudkin, and H. Hondermarck
Nerve Growth Factor Receptor TrkA Signaling in Breast Cancer Cells Involves Ku70 to Prevent Apoptosis
Mol. Cell. Proteomics, November 1, 2007; 6(11): 1842 - 1854.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
F. Causeret, T. Jacobs, M. Terao, O. Heath, M. Hoshino, and M. Nikolic
Neurabin-I Is Phosphorylated by Cdk5: Implications for Neuronal Morphogenesis and Cortical Migration
Mol. Biol. Cell, November 1, 2007; 18(11): 4327 - 4342.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Uvarov, A. Ludwig, M. Markkanen, P. Pruunsild, K. Kaila, E. Delpire, T. Timmusk, C. Rivera, and M. S. Airaksinen
A Novel N-terminal Isoform of the Neuron-specific K-Cl Cotransporter KCC2
J. Biol. Chem., October 19, 2007; 282(42): 30570 - 30576.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
D. A. Alvarez-Arias and K. S. Campbell
Protein Kinase C Regulates Expression and Function of Inhibitory Killer Cell Ig-Like Receptors in NK Cells
J. Immunol., October 15, 2007; 179(8): 5281 - 5290.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
J. M. Stommel, A. C. Kimmelman, H. Ying, R. Nabioullin, A. H. Ponugoti, R. Wiedemeyer, A. H. Stegh, J. E. Bradner, K. L. Ligon, C. Brennan, et al.
Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies
Science, October 12, 2007; 318(5848): 287 - 290.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
E. Sjottem, C. Rekdal, G. Svineng, S. S. Johnsen, H. Klenow, R. D. Uglehus, and T. Johansen
The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription
Nucleic Acids Res., October 8, 2007; 35(19): 6648 - 6662.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Hlavanda, E. Klement, E. Kokai, J. Kovacs, O. Vincze, N. Tokesi, F. Orosz, K. F. Medzihradszky, V. Dombradi, and J. Ovadi
Phosphorylation Blocks the Activity of Tubulin Polymerization-promoting Protein (TPPP): IDENTIFICATION OF SITES TARGETED BY DIFFERENT KINASES
J. Biol. Chem., October 5, 2007; 282(40): 29531 - 29539.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
D. B. Finkelstein, S. Mukatira, P. K. Mehta, J. C. Obenauer, X. Su, R. G. Webster, and C. W. Naeve
Persistent Host Markers in Pandemic and H5N1 Influenza Viruses
J. Virol., October 1, 2007; 81(19): 10292 - 10299.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
N. Paffett-Lugassy, N. Hsia, P. G. Fraenkel, B. Paw, I. Leshinsky, B. Barut, N. Bahary, J. Caro, R. Handin, and L. I. Zon
Functional conservation of erythropoietin signaling in zebrafish
Blood, October 1, 2007; 110(7): 2718 - 2726.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. Magnani, N. R. Nayak, M. Mazarei, L. M. A. Dirk, and R. L. Houtz
Polypeptide Substrate Specificity of PsLSMT: A SET DOMAIN PROTEIN METHYLTRANSFERASE
J. Biol. Chem., September 21, 2007; 282(38): 27857 - 27864.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
S. Feng, M. Ye, H. Zhou, X. Jiang, X. Jiang, H. Zou, and B. Gong
Immobilized Zirconium Ion Affinity Chromatography for Specific Enrichment of Phosphopeptides in Phosphoproteome Analysis
Mol. Cell. Proteomics, September 1, 2007; 6(9): 1656 - 1665.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
J. A. Martel, D. Michael, G. Fejes-Toth, and A. Naray-Fejes-Toth
Melanophilin, a novel aldosterone-induced gene in mouse cortical collecting duct cells
Am J Physiol Renal Physiol, September 1, 2007; 293(3): F904 - F913.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
P. Maurel, S. Einheber, J. Galinska, P. Thaker, I. Lam, M. B. Rubin, S. S. Scherer, Y. Murakami, D. H. Gutmann, and J. L. Salzer
Nectin-like proteins mediate axon Schwann cell interactions along the internode and are essential for myelination
J. Cell Biol., August 27, 2007; 178(5): 861 - 874.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
B. A. Jonas, N. Varlakhanova, F. Hayakawa, M. Goodson, and M. L. Privalsky
Response of SMRT (Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor) and N-CoR (Nuclear Receptor Corepressor) Corepressors to Mitogen-Activated Protein Kinase Kinase Kinase Cascades Is Determined by Alternative mRNA Splicing
Mol. Endocrinol., August 1, 2007; 21(8): 1924 - 1939.
[Abstract] [Full Text] [PDF]

Home page
 Protein Eng Des SelHome page
Y.-R. Tang, Y.-Z. Chen, C. A. Canchaya, and Z. Zhang
GANNPhos: a new phosphorylation site predictor based on a genetic algorithm integrated neural network
Protein Eng. Des. Sel., August 1, 2007; 20(8): 405 - 412.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
M. A. Stiffler, J. R. Chen, V. P. Grantcharova, Y. Lei, D. Fuchs, J. E. Allen, L. A. Zaslavskaia, and G. MacBeath
PDZ Domain Binding Selectivity Is Optimized Across the Mouse Proteome
Science, July 20, 2007; 317(5836): 364 - 369.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
N. Kumar and D. Mohanty
MODPROPEP: a program for knowledge-based modeling of protein-peptide complexes
Nucleic Acids Res., July 13, 2007; 35(suppl_2): W549 - W555.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
Y.-H. Wong, T.-Y. Lee, H.-K. Liang, C.-M. Huang, T.-Y. Wang, Y.-H. Yang, C.-H. Chu, H.-D. Huang, M.-T. Ko, and J.-K. Hwang
KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns
Nucleic Acids Res., July 13, 2007; 35(suppl_2): W588 - W594.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
E. Damoc, C. S. Fraser, M. Zhou, H. Videler, G. L. Mayeur, J. W. B. Hershey, J. A. Doudna, C. V. Robinson, and J. A. Leary
Structural Characterization of the Human Eukaryotic Initiation Factor 3 Protein Complex by Mass Spectrometry
Mol. Cell. Proteomics, July 1, 2007; 6(7): 1135 - 1146.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
P. K. Singh, Y. Wen, B. J. Swanson, K. Shanmugam, A. Kazlauskas, R. L. Cerny, S. J. Gendler, and M. A. Hollingsworth
Platelet-Derived Growth Factor Receptor {beta}-Mediated Phosphorylation of MUC1 Enhances Invasiveness in Pancreatic Adenocarcinoma Cells
Cancer Res., June 1, 2007; 67(11): 5201 - 5210.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
U. E. E. Rennefahrt, S. W. Deacon, S. A. Parker, K. Devarajan, A. Beeser, J. Chernoff, S. Knapp, B. E. Turk, and J. R. Peterson
Specificity Profiling of Pak Kinases Allows Identification of Novel Phosphorylation Sites
J. Biol. Chem., May 25, 2007; 282(21): 15667 - 15678.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Wang, S.-J. Ding, W. Wang, J. M. Jacobs, W.-J. Qian, R. J. Moore, F. Yang, D. G. Camp II, R. D. Smith, and R. L. Klemke
Profiling signaling polarity in chemotactic cells
PNAS, May 15, 2007; 104(20): 8328 - 8333.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
G. G. Leparc and R. D. Mitra
Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human
Nucleic Acids Res., May 11, 2007; 35(10): 3192 - 3202.
[Abstract] [Full Text] [PDF]